Results 41 to 50 of about 66,767 (235)

Cytosolic proteome profiling of aminoglycosides resistant Mycobacterium tuberculosis clinical isolates using MALDI-TOF/MS

Frontiers in Microbiology, 2016
Emergence of extremely drug resistant tuberculosis (XDR-TB) is the consequence of the failure of second line TB treatment. Aminoglycosides are the important second line anti-TB drugs used to treat the multi drug resistant tuberculosis (MDR-TB).
Divakar Sharma, Manju Lata, Rananjay Singh, Nirmala Deo, Krishnamurthy Venkatesan, Deepa Bisht   +5 more
doaj   +1 more source

Clustering of leprosy beyond the household level in a highly endemic setting on the Comoros, an observational study

BMC Infectious Diseases, 2019
Background The island of Anjouan (Comoros) is highly endemic for leprosy with an annual incidence of 5–10/10,000. In May/June, 2015 single-dose Rifampicin post-exposure prophylaxis (SDR-PEP) was administered to 269 close contacts of 70 leprosy-patients ...
Nimer Ortuno-Gutierrez, Abdallah Baco, Sofie Braet, Assoumani Younoussa, Aboubacar Mzembaba, Zahara Salim, Mohamed Amidy, Saverio Grillone, Bouke C. de Jong, Jan Hendrik Richardus, Epco Hasker   +10 more
doaj   +1 more source

Human immunodeficiency virus and leprosy: an update.

, 2011
Coinfection with human immunodeficiency virus (HIV) has a major effect on the natural history of many infectious diseases, particularly mycobacterial diseases.
Lambert, Saba M, Saba M. Lambert, Diana N.J. Lockwood, Lockwood, Diana NJ   +3 more
core   +1 more source

Introducing leprosy post-exposure prophylaxis into the health systems of India, Nepal and Indonesia: a case study

BMC Health Services Research, 2017
Background Leprosy has a wide range of clinical and socio-economic consequences. India, Indonesia and Nepal contribute significantly to the global leprosy burden. After integration, the health systems are pivotal in leprosy service delivery.
A. Tiwari, L. Mieras, K. Dhakal, M. Arif, S. Dandel, J. H. Richardus, LPEP Study Group   +6 more
doaj   +1 more source

Efficacy of autologous platelet-rich plasma therapy versus topical Minoxidil in men with moderate androgenetic alopecia: a randomized open-label trial

Journal of Dermatological Treatment, 2023
Background Platelet-rich plasma (PRP) is an adjunctive treatment in androgenetic alopecia (AGA). Its role as a monotherapy, when compared to FDA-approved therapies in moderate grades of androgenetic alopecia is not established.
Mithinkumar Balasundaram, Rashmi Kumari, Sivaranjini Ramassamy   +2 more
doaj   +1 more source

Early diagnosis of neuropathy in leprosy: comparing diagnostic tests in a large prospective study (the INFIR Cohort Study) [PDF]

, 2008
BackgroundLeprosy is the most frequent treatable neuromuscular disease. Yet, every year, thousands of patients develop permanent peripheral nerve damage as a result of leprosy.
Wilder-Smith, Einar P, Pramila Barkataki, van Brakel, Wim H, van Brakel Wim H., Wim H van Brakel, Diana N J Lockwood, Einar P Wilder-Smith, Nicholls Peter G., Peter G Nicholls, Wilder-Smith Einar P., Nicholls, Peter G, Lockwood Diana N. J., Das Loretta, INFIR Study Group, Nicholls, Peter G., Lockwood, Diana N.J, Das, Loretta, Barkataki, Pramila, Barkataki Pramila, van Brakel, W.H., Loretta Das, Wilder-Smith, Einar P., Lockwood, Diana NJ   +22 more
core   +1 more source

EXPERIMENTAL STUDY OF SPECIFIC ACTIVITY OF 1,3-DIAZINON-4 COMPOUND PYaTdl DERIVATIVE IN VIVO

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Study anti-leprosy activity of a 1.3-diazinon-4 compound derivative under the laboratory code PYaTd 1 on the model of intra-plantar infection of mice and evaluate the character of its antibacterial effect. Materials and methods.
S. A. Luzhnova, M. Yu. Yushin, A. V. Voronkov, S. A. Osychenko, N. M. Gabitova, E. A. Yurtaeva   +5 more
doaj   +1 more source

Tracing leprosy trends in Pakistan: a two-decade analysis of geographic and demographic shifts (2001–2023)

BMC Global and Public Health
Background Leprosy, or Hansen’s disease, is caused by Mycobacterium leprae and can lead to severe disabilities, social marginalisation and reduced quality of life.
Anil Fastenau, Nena Sophie Van Heesewijk, Matthew Willis, Paul Saunderson, Fabian Schlumberger, Ali Murtaza, Muhammed Iqbal, Abdul Salam, Sophie CW. Unterkircher, Elias Treml, Nimer Ortuño-Gutiérrez, Thomas Hambridge   +11 more
doaj   +1 more source

Human Fibroblast‐Myeloid cell tissue atlas across lung, synovium, skin and heart

Arthritis &Rheumatology, Accepted Article.
Background The availability of single‐cell RNA sequencing (scRNAseq data) in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Protocol of a comparative multicentric non inferiority clinical trial of WHO MBMDT with a new monthly chemotherapy regimen containing rifampicin, moxifloxacin and clarithromycin (RMC) on multibacillary patients from India

Trials
Background Current WHO MBMDT regimen has largely been successful in treating leprosy patients since 1984, when it was implemented worldwide. According to clinical presentation, pauci and multibacillary leprosy, the regimen is also given for 6 or 12 ...
Joydeepa Darlong, Samrun Nessa, Itu Singh, Utpal Sengupta, Reeta Devi, Kartikeyan Govindasamy, Neeta Maximus, Vandana Elkana, Anamika Haldar, Ann Miriam Jose, Sylvia Jayakumar   +10 more
doaj   +1 more source