Results 41 to 50 of about 66,916 (244)

Protocol of a comparative multicentric non inferiority clinical trial of WHO MBMDT with a new monthly chemotherapy regimen containing rifampicin, moxifloxacin and clarithromycin (RMC) on multibacillary patients from India

Trials
Background Current WHO MBMDT regimen has largely been successful in treating leprosy patients since 1984, when it was implemented worldwide. According to clinical presentation, pauci and multibacillary leprosy, the regimen is also given for 6 or 12 ...
Joydeepa Darlong, Samrun Nessa, Itu Singh, Utpal Sengupta, Reeta Devi, Kartikeyan Govindasamy, Neeta Maximus, Vandana Elkana, Anamika Haldar, Ann Miriam Jose, Sylvia Jayakumar   +10 more
doaj   +1 more source

EXPERIMENTAL STUDY OF SPECIFIC ACTIVITY OF 1,3-DIAZINON-4 COMPOUND PYaTdl DERIVATIVE IN VIVO

Журнал микробиологии, эпидемиологии и иммунобиологии, 2016
Aim. Study anti-leprosy activity of a 1.3-diazinon-4 compound derivative under the laboratory code PYaTd 1 on the model of intra-plantar infection of mice and evaluate the character of its antibacterial effect. Materials and methods.
S. A. Luzhnova, M. Yu. Yushin, A. V. Voronkov, S. A. Osychenko, N. M. Gabitova, E. A. Yurtaeva   +5 more
doaj   +1 more source

Human Fibroblast–Myeloid Cell Tissue Atlas Across the Lungs, Synovium, Skin, and Heart

Arthritis &Rheumatology, EarlyView.
Objective The availability of single‐cell RNA sequencing (scRNAseq) data in different tissues and disease states provides an opportunity to compare cellular subsets and identify common and unique cellular activation. In this study, we aimed to characterize shared and tissue‐specific myeloid and stromal phenotypes and to uncover key cellular subtypes ...
Lucy MacDonald, Katerina Apostolopoulou, Olympia Hardy, Melpomeni Toitou, Gabriela Kania, Przemyslaw Blyszczuk, Raphael Micheroli, Thomas D. Otto, Mariola Kurowska‐Stolarska, Caroline Ospelt   +9 more
wiley   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

‘You Can Be Simultaneously Powerful and Marginalised at the Same Time in Different Ways’. An Intersectional Examination of Barriers and Facilitators of Help‐Seeking for Eating Disorders by People From Under‐Served Groups

European Eating Disorders Review, EarlyView.
ABSTRACT Objective To explore barriers and facilitators to help‐seeking by people from under‐served groups in eating disorders (EDs). Methods Seventeen participants with lived experience of an ED, identifying as members of groups traditionally under‐served in ED research (ethnic minority, sexual or gender minority, or men), took part in semi‐structured
Jessica Wilkins, Lucy Gallagher, Karina L. Allen, Ulrike Schmidt   +3 more
wiley   +1 more source

Health System Resilience and Afghan Refugee Health in Pakistan: An Exploratory Study of Challenges and Pathways to Inclusion

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Pakistan has hosted Afghan refugees for more than four decades, in one of the world's most protracted displacements of people. Afghan refugees receive health services through United Nations High Commissioner for Refugees (UNHCR) and non‐governmental organisation (NGO) supported programmes alongside public sector facilities at every tier.
Zahid Ali Memon, Asma Ummad, Amina Olabi, Natasha Palmer, Sophie Witter   +4 more
wiley   +1 more source

Does induction or augmentation of labor increase the risk of postpartum hemorrhage in pregnant women with anemia? A multicenter prospective cohort study in India

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 299-309, April 2025.
Abstract Objective To investigate whether induction/augmentation of labor in pregnant women with anemia increases the risk of postpartum hemorrhage (PPH) and whether this risk varied by indications for labor induction/augmentation and by anemia severity in pregnancy.
Tuck Seng Cheng, Farzana Zahir, Carolin Solomi V, Ashok Verma, Sereesha Rao, Saswati Sanyal Choudhury, Gitanjali Deka, Pranabika Mahanta, Swapna Kakoty, Robin Medhi, Shakuntala Chhabra, Anjali Rani, Amrit Bora, Indrani Roy, Bina Minz, Omesh Kumar Bharti, Rupanjali Deka, Charles Opondo, David Churchill, Marian Knight, Jennifer J. Kurinczuk, Manisha Nair   +21 more
wiley   +1 more source

Predicting neuropathy and reactions in leprosy at diagnosis and before incident events. Results from the INFIR cohort study [PDF]

, 2009
BackgroundLeprosy is a disease of skin and peripheral nerves. The process of nerve injury occurs gradually through the course of the disease as well as acutely in association with reactions. The INFIR (ILEP Nerve Function Impairment and Reactions) Cohort
Smith, W Cairns S, Sundar Rao, P.S.S., Diana N J Lockwood, Einar P Wilder-Smith, Rao, P S S Sundar, Van Brakel, W.H., Das, Loretta, W Cairns S Smith, Jadhav Rupendra, Jadhav, R., Wilder-Smith, E.P., Barkataki, P., Wim H van Brakel, Sujai Suneetha, P S S Sundar Rao, Smith, W., Lockwood Diana N. J., Nicholls, P.G., Barkataki Pramila, Wilder-Smith, Einar P., Lockwood, D.N., Smith, W. Cairns S., Lockwood, Diana N J, Lavanya Suneetha, Pramila Barkataki, Suneetha Lavanya, Jadhav, Rupendra, Smith, W.C.S., Nicholls Peter G., Sundar Rao, PSS, Peter G Nicholls, Suneetha, L., Das Loretta, Smith W. Cairns S., Loretta Das, Das, L., van Brakel, Wim H., Lockwood, Diana NJ, Lockwood, Diana N.J., Wilder-Smith, Einar P, Suneetha, Sujai, Lockwood, D.N.J., Suneetha Sujai, Brakel, W.H. van, Suneetha, Lavanya, van Brakel, Wim H, Sundar Rao P. S. S., van Brakel Wim H., Suneetha, S., Wilder-Smith Einar P., Rao, P.S.S.S., Nicholls, Peter G, Rupendra Jadhav, Barkataki, Pramila   +53 more
core   +1 more source

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni, Niccolò Capurro, Alessandro Svizzero, Valeria Brazzelli   +3 more
wiley   +1 more source

Human beta-defensin 3 is up-regulated in cutaneous leprosy type 1 reactions. [PDF]

, 2012
BACKGROUND: Leprosy, a chronic granulomatous disease affecting the skin and nerves, is caused by Mycobacterium leprae (M. leprae). The type of leprosy developed depends upon the host immune response.
Chrissy H Roberts, Walker Stephen L., Deanna A Hagge, Anna L Cogen, Diana N J Lockwood, Deanna A. Hagge, Stephen L. Walker, Anna L. Cogen, Kapil D. Neupane, Neupane, Kapil D, Diana N. J. Lockwood, Lockwood, Diana NJ, Neupane Kapil D., Khadge, Saraswoti, Walker, Stephen L, Kapil D Neupane, Hagge, Deanna A, Cogen Anna L., Saraswoti Khadge, Stephen L Walker, Roberts Chrissy H., Lockwood Diana N. J., Hagge Deanna A., Khadge Saraswoti, Roberts, Chrissy H, Cogen, Anna L, Chrissy H. Roberts   +26 more
core   +1 more source