Results 31 to 40 of about 66,916 (244)

Cytosolic proteome profiling of aminoglycosides resistant Mycobacterium tuberculosis clinical isolates using MALDI-TOF/MS

Frontiers in Microbiology, 2016
Emergence of extremely drug resistant tuberculosis (XDR-TB) is the consequence of the failure of second line TB treatment. Aminoglycosides are the important second line anti-TB drugs used to treat the multi drug resistant tuberculosis (MDR-TB).
Divakar Sharma, Manju Lata, Rananjay Singh, Nirmala Deo, Krishnamurthy Venkatesan, Deepa Bisht   +5 more
doaj   +1 more source

Social distance and spatial distance are not the same, observations on the use of GIS in leprosy epidemiology [PDF]

, 2008
Contacts of leprosy patients have a higher risk of developing clinical leprosy. Being a contact is defined socially, but with the introduction of geographical information systems (GIS) in infectious disease epidemiology, it is necessary to relate spatial
Fischer, E.A.J., pahan, D., Hoeven, T.A., Hoeven, T.A. (Theun), Pahan, D. (David), Fischer, E.A.J. (Egil), Richardus, J.H. (Jan Hendrik)   +6 more
core   +1 more source

Clustering of leprosy beyond the household level in a highly endemic setting on the Comoros, an observational study

BMC Infectious Diseases, 2019
Background The island of Anjouan (Comoros) is highly endemic for leprosy with an annual incidence of 5–10/10,000. In May/June, 2015 single-dose Rifampicin post-exposure prophylaxis (SDR-PEP) was administered to 269 close contacts of 70 leprosy-patients ...
Nimer Ortuno-Gutierrez, Abdallah Baco, Sofie Braet, Assoumani Younoussa, Aboubacar Mzembaba, Zahara Salim, Mohamed Amidy, Saverio Grillone, Bouke C. de Jong, Jan Hendrik Richardus, Epco Hasker   +10 more
doaj   +1 more source

Protocol, rationale and design of PEOPLE (Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar): a cluster randomized trial on effectiveness of different modalities of implementation of post-exposure prophylaxis of leprosy contacts

BMC Infectious Diseases, 2019
Background Leprosy is an ancient infectious disease with a global annual incidence that has plateaued above 200,000 new cases since over a decade. New strategies are required to overcome this stalemate.
Nimer Ortuno-Gutierrez, Assoumani Younoussa, Andriamira Randrianantoandro, Sofie Braet, Bertrand Cauchoix, Stéphanie Ramboarina, Abdallah Baco, Aboubacar Mzembaba, Zahara Salim, Mohamed Amidy, Saverio Grillone, Jan Hendrik Richardus, Bouke C. de Jong, Epco Hasker   +13 more
doaj   +1 more source

Introducing leprosy post-exposure prophylaxis into the health systems of India, Nepal and Indonesia: a case study

BMC Health Services Research, 2017
Background Leprosy has a wide range of clinical and socio-economic consequences. India, Indonesia and Nepal contribute significantly to the global leprosy burden. After integration, the health systems are pivotal in leprosy service delivery.
A. Tiwari, L. Mieras, K. Dhakal, M. Arif, S. Dandel, J. H. Richardus, LPEP Study Group   +6 more
doaj   +1 more source

Efficacy of autologous platelet-rich plasma therapy versus topical Minoxidil in men with moderate androgenetic alopecia: a randomized open-label trial

Journal of Dermatological Treatment, 2023
Background Platelet-rich plasma (PRP) is an adjunctive treatment in androgenetic alopecia (AGA). Its role as a monotherapy, when compared to FDA-approved therapies in moderate grades of androgenetic alopecia is not established.
Mithinkumar Balasundaram, Rashmi Kumari, Sivaranjini Ramassamy   +2 more
doaj   +1 more source

Anti-neutrophil cytoplasmic antibodies (ANCA) in the clinical forms of leprosy [PDF]

, 1998
Anti-neutrophil cytoplasmic antibodies (ANCA) are autoantibodies against enzymes present in primary granules of neutrophils and lysosomes of monocytes detected in systemic vasculitis and in other diseases, including infections, ANCA are markers of active
Ferraz, AAF, Freire, BFA, Ura, S., Queluz, Thais Helena Abrahão Thomaz, Nakayama, E.   +4 more
core   +4 more sources

Early diagnosis of neuropathy in leprosy: comparing diagnostic tests in a large prospective study (the INFIR Cohort Study) [PDF]

, 2008
BackgroundLeprosy is the most frequent treatable neuromuscular disease. Yet, every year, thousands of patients develop permanent peripheral nerve damage as a result of leprosy.
Wilder-Smith, Einar P, Pramila Barkataki, van Brakel, Wim H, van Brakel Wim H., Wim H van Brakel, Diana N J Lockwood, Einar P Wilder-Smith, Nicholls Peter G., Peter G Nicholls, Wilder-Smith Einar P., Nicholls, Peter G, Lockwood Diana N. J., Das Loretta, INFIR Study Group, Nicholls, Peter G., Lockwood, Diana N.J, Das, Loretta, Barkataki, Pramila, Barkataki Pramila, van Brakel, W.H., Loretta Das, Wilder-Smith, Einar P., Lockwood, Diana NJ   +22 more
core   +1 more source

Tracing leprosy trends in Pakistan: a two-decade analysis of geographic and demographic shifts (2001–2023)

BMC Global and Public Health
Background Leprosy, or Hansen’s disease, is caused by Mycobacterium leprae and can lead to severe disabilities, social marginalisation and reduced quality of life.
Anil Fastenau, Nena Sophie Van Heesewijk, Matthew Willis, Paul Saunderson, Fabian Schlumberger, Ali Murtaza, Muhammed Iqbal, Abdul Salam, Sophie CW. Unterkircher, Elias Treml, Nimer Ortuño-Gutiérrez, Thomas Hambridge   +11 more
doaj   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source