Results 31 to 40 of about 66,767 (235)

Cytokine and protein markers of leprosy reactions in skin and nerves: baseline results for the North Indian INFIR cohort. [PDF]

, 2011
BACKGROUND: Previous studies investigating the role of cytokines in the pathogenesis of leprosy have either been on only small numbers of patients or have not combined clinical and histological data.
Lavanya Suneetha, Mohammed Ismail, Ismail Mohammed, Suneetha Lavanya, Diana N J Lockwood, Nicholls, Peter, Chaduvula Meher Vani, Smith W. C., Wim van Brakel, Diana N. J. Lockwood, Lockwood, Diana NJ, Sagili Karuna Devi, Smith, WC, Mohammed, Ismail, Suneetha, Sujai, Suneetha Sujai, van Brakel Wim, Suneetha, Lavanya, Sagili, Karuna Devi, van Brakel, Wim, Karuna Devi Sagili, Sujai Suneetha, Lockwood Diana N. J., Nicholls Peter, W. C. Smith, W C Smith, Chaduvula, Meher Vani, Peter Nicholls, Meher Vani Chaduvula   +28 more
core   +1 more source

The spatial distribution of leprosy in four villages in Bangladesh: an observational study. [PDF]

, 2008
BACKGROUND: There is a higher case-detection rate for leprosy among spatially proximate contacts such as household members and neighbors. Spatial information regarding the clustering of leprosy can be used to improve intervention strategies.
Richardus JH, Richardus, Jh, EAJ Fischer, Richardus, J.H., Fischer, Eaj, Oskam, L. (Linda), pahan, D., Fisher, E. (Eric), Pahan D, Chowdhury SK, D Pahan, Chowdhury, Sk, Chowdhury, S. (Susmita), Fischer EAJ, SK Chowdhury, Oskam L, Pahan, D. (David), Oskam, L, Chowdhury, S.K., Pahan, D, Fischer, E.A.J., Oskam, L., Richardus, Jan hendrik; id_orcid, L Oskam, Richardus, J.H. (Jan Hendrik), JH Richardus   +25 more
core   +2 more sources

Leprosy [PDF]

Clinical Microbiology Reviews, 1988
Leprosy affects over 10 million people in the world. The disease is a model of graded cell-mediated immunity, in this case to the causative organism, Mycobacterium leprae. The clinical manifestations are due to (i) bacterial progression, (ii) immunologic responses of the host, (iii) peripheral nerve damage due to either or both bacterial progression ...
R C, Hastings, T P, Gillis, J L, Krahenbuhl, S G, Franzblau   +3 more
openaire   +2 more sources

Analysis of antibody and cytokine markers for leprosy nerve damage and reactions in the INFIR cohort in India. [PDF]

, 2011
BACKGROUND: The ILEP Nerve Function Impairment in Reaction (INFIR) is a cohort study designed to identify predictors of reactions and nerve function impairment (NFI) in leprosy.
Vidyagouri Shinde, Lavanya Suneetha, Karuna Devi, Wim H. van Brakel, Shinde, V., Suneetha Lavanya, Diana N J Lockwood, Jadhav, Rupendra, Nicholls Peter G., Peter G Nicholls, Chaduvula Meher Vani, Suneetha, L., Kamble Ravindra, Devi, K., Raju, Renuka, Jadhav Rupendra, Devi Karuna, Peter G. Nicholls, Diana N. J. Lockwood, Kamble, Ravindra, Lockwood, Diana NJ, Jadhav, R., Chaduvula, M.V., Suneetha, Sujai, Lockwood, D.N.J., Suneetha Sujai, Suneetha, Lavanya, van Brakel, Wim H, van Brakel Wim H., Wim H van Brakel, Raju, R., Suneetha, S., Devi, Karuna, Sujai Suneetha, Nicholls, Peter G, Kamble, R., Lockwood Diana N. J., Rupendra Jadhav, Nicholls, P.G., Shinde, Vidyagouri, Chaduvula, Meher Vani, Shinde Vidyagouri, van Brakel, W.H., Raju Renuka, Renuka Raju, Ravindra Kamble, Meher Vani Chaduvula   +46 more
core   +1 more source

The Impact of Leprosy on Marital Relationships and Sexual Health among Married Women in Eastern Nepal

Journal of Tropical Medicine, 2016
Background. Leprosy is one of the most stigmatized diseases known today. The stigma surrounding leprosy can be a major burden and affects many dimensions of a person’s life, including intimate relationships.
Anna T. van ’t Noordende, Wim H. van Brakel, Nandlal Banstola, Krishna P. Dhakal   +3 more
doaj   +1 more source

Relationship between psychological health and quality of life of people affected by leprosy in the community in Guangdong province, China: a cross-sectional study

BMC Public Health, 2019
Background This paper investigates the relationship between psychological health and quality of life (QOL) of people affected by leprosy (PAL) living in a community in Guangdong province, China.
Mingzhou Xiong, Xiaohua Wang, Ting Su, Bin Yang, Ming Li, Daocheng Zheng   +5 more
doaj   +1 more source

Leprosy in elderly and children among new cases – A 3-year retrospective study

Indian Dermatology Online Journal, 2021
Background: Leprosy occurs in all age groups, with adults constituting the majority. However, leprosy in children always drew the attention of epidemiologists as a guide to transmission of leprosy.
Potharaju Arunraghav, Kallappa Herakal
doaj   +1 more source

Evaluation of the economic burden of leprosy among migrant and resident patients in Guangdong Province, China

BMC Infectious Diseases, 2017
Background A lot of time and money was needed during the diagnosis and treatment process of leprosy, the delayed leprosy would also impair the labor capability of patients as well, and these put a heavy burden for the leprosy patients.
Mingzhou Xiong, Ming Li, Daocheng Zheng, Xiaohua Wang, Ting Su, Yongfeng Chen, Bin Yang   +6 more
doaj   +1 more source

Negligible risk of inducing resistance in Mycobacterium tuberculosis with single-dose rifampicin as post-exposure prophylaxis for leprosy [PDF]

, 2016
Post-exposure prophylaxis (PEP) for leprosy is administered as one single dose of rifampicin (SDR) to the contacts of newly diagnosed leprosy patients. SDR reduces the risk of developing leprosy among contacts by around 60 % in the first 2-3 years after ...
Richard Anthony, Steinmann, P. (Peter), Mieras, Liesbeth, Bratschi, M W, Jan Hendrik Richardus, Kasang, C. (Christa), Arielle Cavaliero, Mieras, L. (Liesbeth), Lee Reichman, Jacques van den Broek, Cavaliero, A. (Arielle), Christa Kasang, Yew, W.W. (Wing Wai), Anthony, R, van Brakel, Wim, Reichman, L, Emmanuelle Cambau, Anthony, Richard, Steinmann, Peter, Perera, G, Saunderson, P. (Paul), Saunderson, Paul, Cavaliero, Arielle, Saunderson, P, Richardus, Jan hendrik; id_orcid, Kasang, Christa, van den Broek, Jacques, Kasang, C, Richardus, J.H. (Jan Hendrik), Cavaliero, A, Cambau, E. (Emmanuelle), Peter Steinmann, Anthony, R. (Richard), Yew, W W, Reichman, L. (Lee), Mieras, L, Yew, Wing Wai, Perera, G. (Geethal), Richardus, Jan Hendrik, Wim van Brakel, Brakel, W.H. (Wim) van, Bratschi, M.W. (Martin W.), Paul Saunderson, van Brakel, W, Cambau, E, Reichman, Lee, van den Broek, J, Bratschi, Martin W., Steinmann, P, Cambau, Emmanuelle, Geethal Perera, Wing Wai Yew, van den Broek, J. (Jacques), Perera, Geethal, Liesbeth Mieras, Martin W. Bratschi   +55 more
core   +1 more source

Protocol, rationale and design of PEOPLE (Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar): a cluster randomized trial on effectiveness of different modalities of implementation of post-exposure prophylaxis of leprosy contacts

BMC Infectious Diseases, 2019
Background Leprosy is an ancient infectious disease with a global annual incidence that has plateaued above 200,000 new cases since over a decade. New strategies are required to overcome this stalemate.
Nimer Ortuno-Gutierrez, Assoumani Younoussa, Andriamira Randrianantoandro, Sofie Braet, Bertrand Cauchoix, Stéphanie Ramboarina, Abdallah Baco, Aboubacar Mzembaba, Zahara Salim, Mohamed Amidy, Saverio Grillone, Jan Hendrik Richardus, Bouke C. de Jong, Epco Hasker   +13 more
doaj   +1 more source