Results 11 to 20 of about 16,966 (241)

POR TRÁS DA LEPTINA: UMA REVISÃO DE LITERATURA

Arquivos de Ciências da Saúde da UNIPAR, 2023
A obesidade é uma doença crônica, multifatorial, que afeta todas as idades e classes sociais. Esta comorbidade tem avançado em decorrência de diversos fatores e sua prevalência está ancorada em diferentes dimensões como as biológicas, sociais ...
Thalita Etiene Willemann de Castro, Valentina de Paula Garcia, Luciano Seraphim Gasques   +2 more
doaj   +2 more sources

Associação entre polimorfismos no gene/receptor da leptina e obesidade: uma revisão de literatura

Revista de Saúde Pública do Paraná, 2020
Mutações na leptina ou em seu receptor causam a denominada obesidade mórbida relacionada à deficiência de leptina congênita, capaz de ser revertida eficazmente pela terapia com leptina.
Joice Cristina Kuchler, Emi Elaine Stefanski Batistti, Cleunir de Fatima Candido de Bortoli, Léia Carolina Lucio   +3 more
doaj   +2 more sources

Relaciones entre estacionalidad, características corporales y leptina en el inicio de la pubertad en vaquillas Bos taurus taurus y Bos taurus indicus en el trópico mexicano

Revista Mexicana de Ciencias Pecuarias, 2022
El estudio analizó, en dos años, los efectos de raza [Brahman (BHM; n= 65); Suizo Europeo (SE; n= 56)], suplementación con Zilpaterol® (ZIL; tratadas o testigo), estación de nacimiento (primavera u otoño) y sus interacciones, sobre superficie corporal ...
Carlos Hernández-López, René Carlos Calderón-Robles, Alejandro Villa-Godoy, Ángel Ríos-Utrera, Sergio Iván Román-Ponce, Everardo González-Padilla   +5 more
doaj   +2 more sources

Decreased Collagen Type I is Associated with Increased Metalloproteinase-2 Activity and Protein Expression of Leptin in the Myocardium of Obese Rats. [PDF]

Arq Bras Cardiol, 2020
Resumo Fundamento A obesidade é um fator de risco para complicações médicas, incluindo o sistema cardiovascular. Há informações limitadas sobre o colágeno no coração obeso.
Silva-Bertani DCTD, Vileigas DF, Mota GAF, Souza SLB, Tomasi LC, Campos DHS, Deus AF, Freire PP, Alves CAB, Padovani CR, Cicogna AC.   +10 more
europepmc   +2 more sources

Obesity‐induced changes in gene expression in feline adipose and skeletal muscle tissue

Journal of Animal Physiology and Animal Nutrition, Volume 107, Issue 5, Page 1262-1278, September 2023., 2023
Abstract Indoor‐confined cats are prone to developing obesity due to a sedentary life and an energy intake exceeding energy requirements. As in humans, feline obesity decreases insulin sensitivity and increases the risk of developing feline diabetes mellitus, but the pathophysiological mechanisms are currently poorly understood.
Kathrine Stenberg, Guy W. Novotny, Thomas A. Lutz, Thomas Mandrup‐Poulsen, Charlotte Reinhard Bjørnvad   +4 more
wiley   +1 more source

Liver‐expressed antimicrobial peptide 2 is associated with improved pancreatic insulin secretion in adults with overweight and obesity

Diabetes, Obesity and Metabolism, Volume 25, Issue 5, Page 1213-1220, May 2023., 2023
Abstract Aims To examine association of liver‐expressed antimicrobial peptide 2 (LEAP2), an endogenous ghrelin antagonist with anorexiant effects, to key cardiometabolic risk factors in people with overweight and obesity. Methods In this cross‐sectional study, we sought to identify associations between LEAP2 levels and cardiometabolic risk factors ...
Romana Stark, Jack Feehan, Aya Mousa, Zane B. Andrews, Barbora de Courten   +4 more
wiley   +1 more source

The unexplored role of sedentary time and physical activity in glucose and lipid metabolism‐related placental mRNAs in pregnant women who are obese: the DALI lifestyle randomised controlled trial

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 129, Issue 5, Page 708-721, April 2022., 2022
Objective We aimed to explore: (i) the association of sedentary time (ST) and physical activity (PA) during pregnancy with the placental expression of genes related to glucose and lipid metabolism in pregnant women who are obese; (ii) maternal metabolic factors mediating changes in these placental transcripts; and (iii) cord blood markers related to ...
P Acosta‐Manzano, B Leopold‐Posch, D Simmons, R Devlieger, S Galjaard, R Corcoy, JM Adelantado, F Dunne, J Harreiter, A Kautzky‐Willer, P Damm, ER Mathiesen, DM Jensen, LL Andersen, M Tanvig, A Lapolla, MG Dalfra, A Bertolotto, E Wender‐Ozegowska, A Zawiejska, DJ Hill, FJ Snoek, JGM Jelsma, G Desoye, MNM van Poppel   +24 more
wiley   +1 more source

Polymorphisms of leptin-melanocortin system genes associated with obesity in an adult population from Barranquilla [PDF]

Biomedica, 2020
Resumen Introducción. La obesidad se considera un grave problema de salud pública y por ello se hacen esfuerzos en la búsqueda de genes como el LEP, el LEPR y el MC4R del sistema leptina-melanocortina, el cual opera en la regulación neuroendocrina de la ...
Garavito P, Mosquera-Heredia MI, Fang L, Payares F, Ruiz M, Arias I, Tuesca R, Navarro É, Silvera-Redondo C.   +8 more
europepmc   +2 more sources

Gamma‐glutamyl transpeptidase elevation is associated with metabolic syndrome, hepatic steatosis, and fibrosis in patients with nonalcoholic fatty liver disease: A community‐based cross‐sectional study

The Kaohsiung Journal of Medical Sciences, Volume 37, Issue 9, Page 819-827, September 2021., 2021
Abstract This study aimed to analyze the association between elevated gamma‐glutamyl transpeptidase (GGT) and metabolic syndrome (MetS), hepatic steatosis, and fibrosis in patients with nonalcoholic fatty liver disease (NAFLD). From August 2013 to August 2018, a community‐based study was conducted in the northeastern part of Taiwan.
Li‐Wei Chen, Mi‐Sio Huang, Yu‐Chiau Shyu, Rong‐Nan Chien   +3 more
wiley   +1 more source

Adiponectin is associated with insulin sensitivity in white European men but not black African men

Diabetic Medicine, Volume 38, Issue 8, August 2021., 2021
Abstract Aims We aimed to assess ethnic differences in inflammatory markers and their relationships with insulin sensitivity and regional adiposity between white European and black African men. Methods A total of 53 white European and 53 black African men underwent assessment of inflammatory markers alongside Dixon‐magnetic resonance imaging to ...
Olah Hakim, Oluwatoyosi Bello, Meera Ladwa, Fariba Shojaee‐Moradie, Nicola Jackson, Janet L. Peacock, A. Margot Umpleby, Geoffrey Charles‐Edwards, Stephanie A. Amiel, Louise M. Goff   +9 more
wiley   +1 more source