Results 201 to 210 of about 40,192 (253)
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Leptomeningeal neoplasms

Current Treatment Options in Neurology, 2007
Leptomeningeal metastasis is becoming an increasingly important late complication of cancer as survival from systemic disease increases, and due to the fact that many novel cancer drugs fail to achieve therapeutic concentrations in the central nervous system.
Jan, Drappatz, Tracy T, Batchelor
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Leptomeningeal metastasis

Current Opinion in Oncology, 2009
Leptomeningeal metastasis occurs in ~5% of all patients with cancer and is the third most common metastatic complication of the central nervous system. Staging of leptomeningeal metastasis includes contrast-enhanced brain and spine magnetic resonance imaging and radionuclide cerebrospinal fluid (CSF) flow study.
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Leptomeningeal metastases

Current Neurology and Neuroscience Reports, 2004
Leptomeningeal metastasis, also known as neoplastic meningitis, carcinomatous meningitis, and meningeal carcinomatosis, occurs when cancer cells gain access to cerebrospinal fluid pathways, travel to multiple sites within the central nervous system, settle, and grow.
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Leptomeningeal Disease

Neurosurgery Clinics of North America, 2011
Leptomeningeal metastasis (LMD) is a lethal complication caused by a variety of cancers, typically developing late in the disease course. It is associated with major neurologic disabilities and short survival. The incidence of LMD may increase because of longer survival of patients who have cancer, and because of the use of newer large-molecule ...
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Leptomeningeal metastasis

2018
Leptomeningeal metastasis (LM) results from dissemination of cancer cells to both the leptomeninges (pia and arachnoid) and cerebrospinal fluid (CSF) compartment. Breast cancer, lung cancer, and melanoma are the most common solid tumors that cause LM.
Sophie, Taillibert, Marc C, Chamberlain
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Leptomeningeal neoplasms

Current Treatment Options in Neurology, 2002
Leptomeningeal metastases are a late, devastating complication of systemic cancer that typically occurs in conjunction with other systemic relapse. The most common neurologic symptoms include headache, altered mentation, and difficult walking. Diagnosis is established by neuroimaging and cerebrospinal fluid analysis. The prognosis is poor with a median
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Primary leptomeningeal melanoma

Journal of Clinical Neuroscience, 2014
Primary melanoma of the central nervous system is a rare melanocytic tumor typically located in the leptomeninges. We report a 57-year-old woman with an intracranial leptomeningeal melanoma who presented with myoclonic seizures. Brain CT scan and MRI revealed a hemorrhagic intracranial tumor. The tumor was completely removed and leptomeningeal melanoma
Zhao-Yu, Xie   +4 more
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Supratentorial leptomeningeal hemangioblastoma

Neurology, 1978
A familial case of von Hippel-Lindau syndrome with a supratentorial leptomeningeal hemangioblastoma is reported. This is the first case in which the meningeal origin of a supratentorial hemangioblastoma has been histologically verified in von Hippel-Lindau syndrome.
K R, Lee   +3 more
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Diagnosis of leptomeningeal metastasis

Clinical Neurology and Neurosurgery, 1987
Forty-one cases of leptomeningeal metastases from solid and hematological tumours were studied clinically and pathologically. Neurological symptoms and signs, cerebrospinal fluid characteristics and radiographic appearance were reviewed. The role of the biochemical markers, computer tomography scans of the brain and myelography in the diagnosis of ...
A, Twijnstra   +2 more
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LEPTOMENINGITIS

Archives of Neurology & Psychiatry, 1930
The arachnoid or intermediate membrane consists essentially of an interlacement of flattened bundles of fine fibrous tissue interspersed with elastic fibers and platelike cells. In addition to the main sheath or the partition, both sides of which are covered with endothelium, numerous trabeculae extend across the subarachnoid space; in places they are ...
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