Results 11 to 20 of about 42,791 (225)

Host-Driven Genetic Diversity of <i>Leptospira</i> in the Americas: A Continental Perspective. [PDF]

Transbound Emerg Dis
Leptospira is a genetically diverse genus of spirochetes comprising over 68 species, including several pathogenic taxa such as L. interrogans, L. santarosai, L. noguchii, and L. weilii. These bacteria infect a wide range of vertebrates, especially mammals, with infected animals serving as renal carriers that excrete the pathogen through urine.
Suárez-Galaz A, Sánchez-Montes S, Torres-Castro M, Chan-Chan R, Yeh-Gorocica A, Moguel-Chin W, Miranda-Caballero CI, Grostieta E, Panti-May A, Ruiz-Piña H, Rodríguez-Vivas RI, Cruz-Romero A, Ojeda-Robertos NF, Reyes-Novelo E.   +13 more
europepmc   +2 more sources

Evaluation of Laboratory Techniques for the Diagnosis of Leptospira-Associated Equine Recurrent Uveitis (ERU) With Focus on the Goldmann-Witmer Coefficient. [PDF]

Vet Ophthalmol
ABSTRACT Purpose To evaluate different laboratory procedures for determining the etiologic diagnosis of equine recurrent uveitis regarding intraocular infection with Leptospira spp. and to establish a diagnostic guideline. Material and Methods Eighty horses with a history of ERU were ophthalmologically examined.
Kirmse L, Thieme K, Doherr MG, Eule JC.
europepmc   +2 more sources

Genotyping Reveals Potential Sources of Human Leptospirosis Outbreaks in Aotearoa New Zealand. [PDF]

Zoonoses Public Health
ABSTRACT Introduction The introduction of PCR testing for leptospirosis in Aotearoa New Zealand has reduced the availability of serotyping data, and current diagnostic PCRs do not routinely genotype Leptospira. This study genotyped Leptospira from PCR‐confirmed human cases between 2016 and 2023 and compared them with genotypes found in animals to ...
Nisa S, Littlejohn S, Fayaz A, Deen S, Sokolova M, Ogbuigwe P, Moinet M, Cookson AL, Collins-Emerson J, Niebuhr CN, Vallee E, Marshall J, Benschop J.   +12 more
europepmc   +2 more sources

Correction to "Expression and Immunogenicity Analysis of Recombinant Leptospira interrogans Surface Protein LigA in Mouse Model". [PDF]

Vet Med Sci
Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
europepmc   +2 more sources

Synanthropic and Wild Animals as Sentinels of Zoonotic Agents: A Study of Leptospira Genotypes Circulating in Northeastern Italy

International Journal of Environmental Research and Public Health, 2023
Leptospirosis is an infectious disease widely reported in veterinary practice and a worldwide zoonosis. In Northeastern Italy, different serogroups and genotypes of Leptospira have been described in ill dogs, the most commonly detected being ...
E. Mazzotta, L. Bellinati, Cristina Bertasio, M. Boniotti, L. Lucchese, L. Ceglie, Federico Martignago, S. Leopardi, A. Natale   +8 more
semanticscholar   +1 more source

Detection of P1 and P2 Subclades of Leptospira carriage in swine in Sri Lanka. [PDF]

BMC Vet Res
Rathnayake N, Muthusinghe D, Vijeyakumaran R, Senarathne P, Bandara V, Sarathkumara Y, Nalinda R, Shiokawa K, Yoshimatsu K, Rajapakse S, Koizumi N, Gamage C.   +11 more
europepmc   +2 more sources

Pathogenic Leptospira are widespread in the urban wildlife of southern California

bioRxiv, 2023
Leptospirosis, the most widespread zoonotic disease in the world, is broadly understudied in multi-host wildlife systems. Knowledge gaps regarding Leptospira circulation in wildlife, particularly in densely populated areas, contribute to frequent ...
Sarah K. Helman, Amanda F. N. Tokuyama, Riley O. Mummah, Mason W. Gamble, Celine E Snedden, B. Borremans, Ana C. R. Gomez, C. Cox, Julianne Nussbaum, Isobel Tweedt, D. Haake, R. Galloway, J. Monzón, S. Riley, Jeff A. Sikich, Justin Brown, A. Friscia, J. Lynch, K. Prager, J. Lloyd-Smith   +19 more
semanticscholar   +1 more source

DNA Capture and Enrichment: A Culture-Independent Approach for Characterizing the Genomic Diversity of Pathogenic Leptospira Species

Microorganisms, 2023
Because they are difficult to culture, obtaining genomic information from Leptospira spp. is challenging, hindering the overall understanding of leptospirosis.
N. E. Stone, Ryelan F. McDonough, Camila Hamond, Karen LeCount, J. Busch, Katherine L Dirsmith, S. Rivera-Garcia, F. Soltero, L. M. Arnold, Zachary P Weiner, R. Galloway, L. Schlater, J. Nally, J. Sahl, D. Wagner   +14 more
semanticscholar   +1 more source

Overcoming problems to produce the recombinant protein LipL21 of Leptospira interrogans

BioTechniques, 2023
The production of leptospiral recombinant proteins in the soluble form and in high yield from Escherichia coli is still a challenge. This work presents the cloning, expression and purification of the outer membrane protein of Leptospira interrogans ...
Maria Beatriz Takahashi, Aline Florencio Teixeira, Ana Lucia Tabet Oller Nascimento   +2 more
doaj   +1 more source

Leptospira Is an Environmental Bacterium That Grows in Waterlogged Soil

Microbiology spectrum, 2022
Since research on Leptospira has focused on pathogenic leptospires, which are supposed to multiply only in animal hosts, the life cycle of saprophytic leptospires has long been a mystery.
Y. Yanagihara, S. Y. Villanueva, Naoki Nomura, Marumi Ohno, Toshiki Sekiya, Chimuka Handabile, M. Shingai, H. Higashi, S. Yoshida, T. Masuzawa, N. Gloriani, M. Saito, H. Kida   +12 more
semanticscholar   +1 more source