Results 11 to 20 of about 19,588 (180)

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Genotyping Reveals Potential Sources of Human Leptospirosis Outbreaks in Aotearoa New Zealand. [PDF]

Zoonoses Public Health
ABSTRACT Introduction The introduction of PCR testing for leptospirosis in Aotearoa New Zealand has reduced the availability of serotyping data, and current diagnostic PCRs do not routinely genotype Leptospira. This study genotyped Leptospira from PCR‐confirmed human cases between 2016 and 2023 and compared them with genotypes found in animals to ...
Nisa S, Littlejohn S, Fayaz A, Deen S, Sokolova M, Ogbuigwe P, Moinet M, Cookson AL, Collins-Emerson J, Niebuhr CN, Vallee E, Marshall J, Benschop J.   +12 more
europepmc   +2 more sources

THE OUTER MEMBRANE OF PATHOGENIC REPRESENTATIVES OF THE LEPTOSPIRA GENIUS

Инфекция и иммунитет, 2014
. Pathogenic leptospires can infect wide spectrum of hosts and they can survive in the environment long time. The outer membrane is the cellular component participated in interaction of microorganisms and environment.
A. N. Vaganova
doaj   +1 more source

Leptospiraand Inflammation [PDF]

Mediators of Inflammation, 2012
Leptospirosis is an important zoonosis and has a worldwide impact on public health. This paper will discuss both the role of immunogenic and pathogenic molecules during leptospirosis infection and possible new targets for immunotherapy against leptospira components.Leptospira, possess a wide variety of mechanisms that allow them to evade the host ...
C. F. Gonçalves-de-Albuquerque, P. Burth, A. R. Silva, M. Younes-Ibrahim, H. C. Castro-Faria-Neto, M. V. Castro-Faria   +5 more
openaire   +3 more sources

The interaction of two novel putative proteins of Leptospira interrogans with E-cadherin, plasminogen and complement components with potential role in bacterial infection

Virulence, 2019
Leptospirosis is a worldwide zoonosis caused by pathogenic species of Leptospira. Leptospires are able to adhere to exposed extracellular matrix in injured tissues and, once in the bloodstream, can survive the attack of the immune system and spread to ...
Leandro T. Kochi, Luis G. V. Fernandes, Gisele O. Souza, Silvio A. Vasconcellos, Marcos B. Heinemann, Eliete C. Romero, Karin Kirchgatter, Ana L. T. O. Nascimento   +7 more
doaj   +1 more source

Revealing of Natural Leptospirosis Focus in Irkutsk Suburb

Эпидемиология и вакцинопрофилактика, 2015
For the first time natural leptospirosis focus was revealed in the Irkutsk suburb in 2012 - 2014 during epizootological inspection of a pond-marsh complex. Total 74 small animals (14 species) were examined, specific fragments of Leptospira DNA were found
E. Yu. Kiseleva, S. A. Borisov, N. V. Breneva, M. B. Sharakshanov, M. V. Chesnokova, A. F. Timoshenko, S. V. Balakhonov   +6 more
doaj   +1 more source

Detection of Leptospira spp. in kidney tissues isolated from rats in the Napu and Bada Highlands of Poso District, Central Sulawesi Province

Jurnal Vektor Penyakit, 2020
Leptospirosis is still a global health problem because it affects human health in rural and urban areas, both in industrialized and developing countries. The aim of the study was to detect Leptospira spp.
Gunawan Gunawan, Tri Wibawa, Mahardika Agus Wijayanti, Hayani Anastasia   +3 more
doaj   +1 more source

Leptospiral Immunoglobulin-Like Domain Proteins: Roles in Virulence and Immunity

Frontiers in Immunology, 2021
The virulence mechanisms required for infection and evasion of immunity by pathogenic Leptospira species remain poorly understood. A number of L. interrogans surface proteins have been discovered, lying at the interface between the pathogen and host ...
David A. Haake, David A. Haake, James Matsunaga, James Matsunaga   +3 more
doaj   +1 more source

Exploring the impact of microbial dysbiosis on ovarian cancer and the therapeutic potential of probiotics

VIEW, EarlyView.
Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li, Nalan Tu, Xin Ning, Yunyan Cong, Fei Wu, Xiuli Zhang, Runrong Li, Yue Xu, Binqiao Wang, Liqin Jin, Yuanming Shen, Jihong Liu   +11 more
wiley   +1 more source

Análise descritiva dos casos confirmados de leptospirose em humanos no Brasil, período de 2010-2019

Journal Health NPEPS, 2021
Objetivo: descrever o número populacional de casos confirmados de leptospirose em humanos no Brasil no período de 2010 a 2019. Método: estudo transversal, pautado em dados secundários, disponíveis no Sistema de Informação de Agravos de Notificação.
Flávio Aparecido da Cruz Magalhães , Rayniel de Moraes Mendes, Andréia Lima Tomé Melo   +2 more
doaj   +1 more source