Expression of sialic acids and other nonulosonic acids in Leptospira [PDF]
, 2012 BackgroundSialic acids are negatively charged nine carbon backbone sugars expressed on mammalian cell surfaces. Sialic acids are part of a larger family of nonulosonic acid (NulO) molecules that includes pseudaminic and legionaminic acids.
Lewis, Amanda L +3 more
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Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
, 2020 The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
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Characterization of Three Novel Adhesins of Leptospira interrogans [PDF]
The American Society of Tropical Medicine and Hygiene, 2013 We report cloning, expression, purification, and characterization of three predicted leptospiral membrane proteins (LIC11360, LIC11009, and LIC11975). In silico analysis and proteinase K accessibility data suggest that these proteins might be surface exposed.
Gabriela H, Siqueira +5 more
openaire +2 more sources
Cloning and sequencing of the virulent gene LipL32 of Leptospira interrogans serovar Autumnalis
Veterinary World, 2013 Aim: To clone the virulent gene LipL32 of Leptospira interrogans serovar Autumnalis and to analyze the sequence with LipL32 gene of other pathogenic serovars of Leptopsira.
Sriram Vamshi Krishna +5 more
doaj +1 more source
Prevalence and Identification of Pathogenic Leptospira in Commensal Rodent From Maumere Flores Origin [PDF]
, 2016 Commensal rat have been report as main source of leptospirosis to humans, but in Indonesia the status of leptospirosis in rats commensal still not widely known. The aim of this study was to calculate the prevalence and identified pathogenic Leptospira in
joharina, A. S. (arum) +4 more
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Identification of Cell-Binding Adhesins of Leptospira interrogans [PDF]
PLoS Neglected Tropical Diseases, 2014 Leptospirosis is a globally distributed bacterial infectious disease caused by pathogenic members of the genus Leptospira. Infection can lead to illness ranging from mild and non-specific to severe, with jaundice, kidney and liver dysfunction, and widespread endothelial damage.
Evangelista, Karen V +5 more
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Macrophages and Galectin 3 Control Bacterial Burden in Acute and Subacute Murine Leptospirosis That Determines Chronic Kidney Fibrosis [PDF]
, 2018 Previous studies have suggested that macrophages may contribute to acute Leptospira dissemination, as well as having a major role in kidney fibrosis. Our aim was to characterize the role of macrophages and galectin 3 (Gal-3) on the survival, clinical ...
Carrera Silva, Eugenio Antonio +10 more
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IS1500, an IS3-like element from Leptospira interrogans [PDF]
Microbiology, 1995 Copies of an insertion-sequence (IS)-like element were isolated from two closely related serovars of Leptospira interrogans sensu stricto. Nucleotide sequence analysis of the 1236 bp element showed a characteristic IS structure with terminal imperfect inverted repeats (IRs) flanking a 1159 bp central region. This element was designated IS1500.
C, Boursaux-Eude +2 more
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Revista do Instituto de Medicina Tropical de São Paulo, 1988 The efficiency of four Leptospira biflexa strains (Buenos Aires, Patoc 1, Rufino and São Paulo) as single antigen in the serodiagnosis in guinea-pigs experimentally infected with seven Leptospira interrogans serovars (canicola, grippotyphosa, hardjo ...
Raul J. S. Girio, Luis A. Mathias
doaj +1 more source
Decay-Accelerating Factor 1 Deficiency Exacerbates Leptospiral-Induced Murine Chronic Nephritis and Renal Fibrosis [PDF]
, 2014 Leptospirosis is a global zoonosis caused by pathogenicLeptospira, which can colonize the proximal renal tubules andpersist for long periods in the kidneys of infected hosts.
Alberdi, Maria Lucrecia +7 more
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