Results 131 to 140 of about 23,892 (247)

Valproic acid for treatment of traumatic brain injury: Study protocol for the VIBRANT prospective randomized trial

Transfusion, EarlyView.
Abstract Background Traumatic brain injury (TBI) carries significant mortality and morbidity in civilian and military populations. Current treatment guidelines for TBI are primarily supportive, and no pharmacological agent exists to attenuate the progression of brain injury.
Maxime A. Visa, Marjorie R. Liggett, Sharnia Lashley, Umar Bhatti, Zaiba A. Dawood, Alvin Anand, Nathan P. Gill, Denise M. Scholtens, Bowen Wang, Hasan B. Alam   +9 more
wiley   +1 more source

Loss of Endothelial YAP/TAZ Reduces the Size of Chronic Stroke Lesions and Alters the Endothelial Environment

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Ischemic stroke remains a leading cause of morbidity and mortality worldwide, with limited treatment options available. Vascular dysfunction is a key pathomechanism, and brain endothelial cells (bECs) play a critical role in determining stroke
Ria Göttert, Majed Kikhia, Marie‐Louise Herzog, Wen Pan, Alexandra Klaus‐Bergmann, January Weiner, Dieter Beule, Samuel Knauss, Golo Kronenberg, Michael Potente, Holger Gerhardt, Matthias Endres, Karen Gertz   +12 more
doaj   +1 more source

Efecto citoprotector del extracto acuoso de hojas de Bixa orellana (achiote) en úlceras gástricas inducidas por indometacina en un modelo de ratones [PDF]

, 2011
Los AINES son uno de los grupos terapéuticos más utilizados gracias a su efecto antiinflamatorio, anti‐pirético y analgésico; son fácilmente accesibles sin prescripción médica, lo que conlleva un alto porcentaje de automedicación.
Ancheta Henríquez, Julio Rodolfo, Guzmán Santamaría, María Guadalupe   +1 more
core  

Serial postoperative peritoneal fluid analyses in horses with naturally‐occurring strangulating and non‐strangulating gastrointestinal lesions

Veterinary Surgery, EarlyView.
Abstract Objective To describe characteristics of postoperative peritoneal fluid following exploratory laparotomy for naturally‐occurring gastrointestinal lesions in horses. Study design Prospective, observational cohort study. Animals A total of 26 client‐owned horses that underwent exploratory laparotomy for naturally‐occurring gastrointestinal ...
Maria E. Granello, Jenna M. Young, Dana B. Cleff, Emma B. M. Banks, Troy N. Trumble   +4 more
wiley   +1 more source

Expression characteristics of dual‐specificity phosphatase 2 and hypoxia‐inducible factor‐1α in acute kidney injury and preliminary study of the effect of dual‐specificity phosphatase 2 on HK‐2 cells

Experimental Physiology, EarlyView.
ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu, Songmin Xue, Lanyan Lin, Xuan Huang, Sisi Chen, Wulaer Adeli, Zulibiya Tuohetiyaer, Suhua Li, Chen Lu   +8 more
wiley   +1 more source

Síndrome compartimental abdominal en el paciente crítico con patología médica [PDF]

, 2012
Estudi observacional de 60 pacients ingressats a la UCI per patologia extraabdominal, que demostra alta incidència de HIA (90%) i que el valor de PIA màxima és marcador pronòstic del SCA però no prediu mortalitat.
Amestoy Torre, Élida, Fernández-Llamazares Rodríguez, Jaume, Marcos Neira, Pilar, Universitat Autònoma de Barcelona. Departament de Cirurgia, Universitat Autònoma de Barcelona. Facultat de Medicina   +4 more
core   +1 more source

Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study

Experimental Physiology, EarlyView.
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey, Richard G. Davies, Brenig L. Gwilym, Benjamin S. Stacey, Danny Walmsley, Michael H. Lewis, Josip Butkovic, Ivan Mumlek, Brad Perry, Zvonomir Vrselja, Shigehiko Ogoh, James A. Pawelczyk, Mohamad Bashir, Richard D. White, Ian M. Williams   +14 more
wiley   +1 more source

Identificación de genes blanco NFAT5 inducidos por hipoxia e hipoxia/reoxigenación [PDF]

, 2016
Tesis (Tecnólogo Médico)El trasplante renal es una de las opciones terapéuticas en la Insuficiencia Renal Crónica Terminal (IRCT). Sin embargo, a pesar de las sofisticadas técnicas de preservación, dicho tejido inevitablemente sufrirá algún daño debido a
Badilla Muñoz, Charlotte Vanessa, Martínez Casanova, Catalina Ester   +1 more
core  

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Neuroprotective Effect of Remote Ischemic Conditioning on Patients Undergoing Intravenous Thrombolysis: A Randomized Controlled Trial

MedComm, Volume 7, Issue 4, April 2026.
Adjunctive remote ischemic conditioning (RIC) administered twice within 24 h after intravenous thrombolysis (IVT) improved cerebral autoregulation, suggesting that RIC exerted neuroprotective effects in patients undergoing IVT. ABSTRACT Intravenous thrombolysis (IVT) is the treatment with the highest level of evidence for acute ischemic stroke, but ...
Shuang Qi, Yang Qu, Jia Liu, Kangjia Song, Yucen Ma, Yao‐De He, Peng Zhang, Yi Gao, Yuli Fu, Pan‐Deng Zhang, Yi Yang, Zhen‐Ni Guo   +11 more
wiley   +1 more source