Results 201 to 210 of about 22,625 (246)

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, Volume 59, Issue 6, June 2026.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source

Heme cascade-triggered nanovesicles for myocardial ischemic core delivery. [PDF]

Bioact Mater
Chen H, Yang Y, Aikebaier M, Wang H, Zheng L, Zhang Y, Zha Q, Shan S, Wang Y, Chen J, Huang F, Li Y, Tang Y, Du Y, Cui W, Yang K, Liu Y.   +16 more
europepmc   +1 more source

Serum Neurofilament Light Chain Predicts Stroke Outcome and is a Potential Marker for Treatment Effects of Neural Stem Cell-derived Extracellular Vesicles in a Rat Stroke Model. [PDF]

Transl Stroke Res
Cannon MK, Fojtik AR, White CM, Swetenburg RL, Stice SL, Savitz SI, Baker EW.   +6 more
europepmc   +1 more source

The NF‐κB Signalling Pathway: Mechanisms, Consequences and Therapeutic Targets

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Nuclear Factor‐kappa B (NF‐κB) is a master transcriptional regulator orchestrating critical cellular processes, predominantly immunity and inflammation. However, its aberrant constitutive activation has emerged as a unifying pathogenetic hallmark across diverse malignancies, autoimmune disorders, and chronic inflammatory diseases.
Bherouz Pourdad, Arash Pourdad
wiley   +1 more source

The Critical Importance of Recognizing De Winter's T-wave Pattern: A Case of Acute Proximal LAD Occlusion by In-Stent Restenosis. [PDF]

Cureus
Chin-Yuan H, Keng-Yi W.
europepmc   +1 more source

Assessment of hESC‐IMRC‐Exo for Cardiac and Cerebral Injuries Post‐Cardiac Arrest Resuscitation: Safety, Pharmacokinetics, and Efficacy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 12, June 2026.
ABSTRACT Cardiac arrest (CA) is a leading cause of death globally. Exosomes derived from mesenchymal stem cells exhibit favourable production, storage, and safety characteristics, making them a promising alternative for post‐CA resuscitation. We assessed the safety, biodistribution, and protective effects of human embryonic stem cell‐derived immunity ...
Huijuan Yang, Xiaodan Zhang, Wenbin Zhang, Xue Wang, Jie Wang, Ziwei Chen, Jinyu Zhu, Yufeng Hu, Lu He, Licai Liang, Jiefeng Xu, Mao Zhang   +11 more
wiley   +1 more source

Limitations and Blind Spots of Diffusion-Weighted Imaging in the Evaluation of Acute Brain Ischemia: A Narrative Review. [PDF]

J Clin Med
Nikolakakis I, Koutroulou I, Mantatzis M, Finitsis S, Grigoriadis N, Karapanayiotides T.   +5 more
europepmc   +1 more source

Novel interactions between the C5‐C5aR1 Axis and IF1: Implications for kidney mitochondrial physiology and ischemia–reperfusion injury

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Ischemia‐reperfusion injury (IRI) is a prevalent condition that predominantly afflicts hospitalized patients, inducing acute kidney injury (AKI). In recent years, complement 5 (C5) and its anaphylatoxin receptor C5aR1 have been implicated in driving kidney IRI and loss of function.
Madison McGraw, Amod Sharma, Dinesh Bhattarai, Neriman Gokden, LeeAnn Macmillan‐Crow, Nirmala Parajuli   +5 more
wiley   +1 more source

Current perspective in acute ischemic stroke: net water uptake and imaging-guided selection as bridges to personalized, tissue-based care. [PDF]

Front Neurol
Broocks G, Werner R, Sentker T, Minnerup J, Kemmling A.   +4 more
europepmc   +1 more source

Contrast‐enhanced ultrasound and photoacoustic imaging to assess early and late renal ischemia‐reperfusion injuries in male mice

Physiological Reports, Volume 14, Issue 12, June 2026.
Abstract Tissue perfusion and oxygenation, key factors of renal ischemia‐reperfusion injury (RIR), can be assessed using contrast‐enhanced ultrasound (CEUS) and photoacoustic (PA) imaging. We hypothesized that early changes in renal perfusion and oxygenation caused by IRI, or protection by mild therapeutic hypothermia (mTH), could be detected and ...
Maxime Schleef, Corentin Tournebize, Christelle Leon, Bruno Pillot, Stéphanie Chanon, Gabriel Bidaux, Laurent Juillard, Fitsum Guebre‐Egziabher, Delphine Baetz, Sandrine Lemoine   +9 more
wiley   +1 more source