Results 21 to 30 of about 23,892 (247)

Intravascular ultrasound observation of the mechanism of no-reflow phenomenon in acute myocardial infarction. [PDF]

PLoS ONE, 2015
To study the mechanism of the no-reflow phenomenon using coronary angiography (CAG) and intravascular ultrasound (IVUS).A total of 120 patients with acute myocardial infarction (AMI) who successfully underwent indwelling intracoronary stent placement by ...
Junxia Li, Longmei Wu, Xinli Tian, Jian Zhang, Yujie Shi   +4 more
doaj   +1 more source

Systemic conditioned medium treatment from interleukin-1 primed mesenchymal stem cells promotes recovery after stroke

Stem Cell Research & Therapy, 2020
Background Mesenchymal stem cells (MSCs) hold great potential as a therapy for stroke and have previously been shown to promote recovery in preclinical models of cerebral ischaemia.
Catriona J. Cunningham, Raymond Wong, Jack Barrington, Sabrina Tamburrano, Emmanuel Pinteaux, Stuart M. Allan   +5 more
doaj   +1 more source

CMRSegTools: An open-source software enabling reproducible research in segmentation of acute myocardial infarct in CMR images.

PLoS ONE, 2022
In the last decade, a large number of clinical trials have been deployed using Cardiac Magnetic Resonance (CMR) to evaluate cardioprotective strategies aiming at reducing the irreversible myocardial damage at the time of reperfusion.
William A Romero R, Magalie Viallon, Joël Spaltenstein, Lorena Petrusca, Olivier Bernard, Loïc Belle, Patrick Clarysse, Pierre Croisille   +7 more
doaj   +1 more source

Culprit Lesion Vessel Size and Risk of Reperfusion Injury in ST‐Segment Elevation Myocardial Infarction: A Cardiac Magnetic Resonance Imaging Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH) are well‐established imaging biomarkers of failed myocardial tissue reperfusion in patients with ST‐segment elevation–myocardial infarction treated with percutaneous coronary
Ivan Lechner, Martin Reindl, Christina Tiller, Magdalena Holzknecht, Fritz Oberhollenzer, Agnes Mayr, Axel Bauer, Bernhard Metzler, Sebastian J. Reinstadler   +8 more
doaj   +1 more source

Endothelial Cell-Based Vascular Bandages for Blood-Brain Barrier Repair and Targeted siRNA Delivery. [PDF]

Adv Sci (Weinh)
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Li Y, Dong Y, He Y, Zheng J, Liu H, Li L, Hao X, Zhao Y, Yang Z, Sun Y, Du Z, Zhao B, Zhou W, Wu H, Zhang T, Wu J, Liu X, Yin X, Chen Z, Xue R, Lou M, Gu Z, Jiang X, Gao J.   +23 more
europepmc   +2 more sources

Efecto del Dimetilsulfóxido (DMSO) y N-Acetilcisteína (NAC) en un modelo animal de Isquemia-Reperfusion renal [PDF]

, 2010
La principal causa de la Insuficiencia renal aguda (IRA) es la isquemia renal, entidad clínica frecuente en escenarios hospitalarios en donde se hace presente la disminución del flujo sanguíneo renal.
Flores, Patricia Eugenia, López Vega, Gabriel Alejandro   +1 more
core  

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source

Transient middle cerebral artery occlusion induces microglial priming in the lumbar spinal cord: a novel model of neuroinflammation

Journal of Neuroinflammation, 2008
Background Middle cerebral artery occlusion (MCAo) in mice results in a brain infarct, the volume of which depends on the length of occlusion. Following permanent occlusion, neuropathological changes – including a robust glial inflammatory response ...
Hill Tracy, Welch Ian, Moisse Katie, Volkening Kathryn, Strong Michael J   +4 more
doaj   +1 more source

DMSO y Acido Ascórbico como terapia de protección en un modelo animal de Isquemia-Reperfusión [PDF]

, 2010
El riñón es uno de los órganos que mayor susceptibilidad presenta a la isquemia, numerosas situaciones clínicas involucran mecanismos que afectan la perfusión de dicho órgano.
Alfaro Cruz, Ligia María, García-Prieto C., Beatriz Eugenia   +1 more
core  

CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis

Advanced Science, EarlyView.
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou, Wan Fu, Shizuo Liu, Zili Zhang, Hanyan Luo, Qing Zhong   +5 more
wiley   +1 more source