Results 31 to 40 of about 23,892 (247)

Absolute Cerebral Blood Flow Infarction Threshold for 3-Hour Ischemia Time Determined with CT Perfusion and 18F-FFMZ-PET Imaging in a Porcine Model of Cerebral Ischemia. [PDF]

PLoS ONE, 2016
CT Perfusion (CTP) derived cerebral blood flow (CBF) thresholds have been proposed as the optimal parameter for distinguishing the infarct core prior to reperfusion.
Eric A Wright, Christopher D d'Esterre, Laura B Morrison, Neil Cockburn, Michael Kovacs, Ting-Yim Lee   +5 more
doaj   +1 more source

Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance (Mobile Stroke Unit—TASTE-A): protocol for a prospective randomised, open-label, blinded endpoint, phase II superiority trial of tenecteplase versus alteplase for ischaemic stroke patients presenting within 4.5 hours of symptom onset to the mobile stroke unit

BMJ Open, 2022
Introduction Mobile stroke units (MSUs) equipped with a CT scanner are increasingly being used to assess and treat stroke patients’ prehospital with thrombolysis and transfer them to the most appropriate hospital for ongoing stroke care and thrombectomy ...
Geoffrey A Donnan, Stephen M Davis, Karen Smith, Vincent Thijs, Philip Choi, Michael Valente, Leonid Churilov, Bruce Campbell, Tissa Wijeratne, Henry Ma, Andrew Bivard, Michael Stephenson, Henry Zhao, Geoffrey Cloud, Bernard Yan, Mark Parsons, Angelos Sharobeam, Skye Coote, Francesca Langenberg, Nawaf Yassi, Anna Balabanski, Angela Dos Santos, Felix Ng, Steve Bernard, Chushuang Chen, Liudmyla Olenko   +25 more
doaj   +1 more source

Historia natural de la oclusión aguda de gran arteria de la circulación cerebral anterior : serie clínica de 120 pacientes [PDF]

, 2012
: Para estudiar la historia natural del ictus isquémico por oclusión de gran vaso de la circulación anterior se seleccionó una muestra prospectiva de pacientes con ictus agudo que no recibieron terapias de reperfusión en los que se confirmó una oclusión ...
Dávalos, Antoni, Escudero Rubí, Domingo, Hernández Pérez, María, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +4 more
core  

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

Advanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Precondicionamiento isquémico a distancia en la revascularización miocárdica de los pacientes diabéticos. ¿Es realmente beneficioso?

Revista Cubana de Anestesiología y Reanimación, 2016
Introducción: una serie de breves períodos de isquemias a distancia, previo al evento isquémico mayor, pueden limitar el daño miocárdico producido por la isquemia crítica y el que se produce posreperfusión.
Rudy Hernández Ortega, Osvaldo González Alfonso, Javier Vázquez Roque, Antonio de Jesús Cabrera Prats, Juliette Marie Suárez López, Raúl Crúz Bóza   +5 more
doaj  

Post-Stroke Depression: Impact of Lesion Location and Methodological Limitations—A Topical Review

Frontiers in Neurology, 2017
Post-stroke depression (PSD) affects approximately one-third of all stroke patients. It hinders rehabilitation and is associated with worse functional outcome and increased mortality.
Alina Nickel, Götz Thomalla
doaj   +1 more source

Preservación de la zona de penumbra en ictus isquémico embólico con Tirofibán en un modelo experimental [PDF]

, 2009
Existe un consenso mundial reconociendo la eficacia de la terapia de reperfusión, dentro de las primeras tres horas del evento, con el activador del plasminógeno tisular (tPA), de forma intravenosa.
Castaneda Vega, Salvador, Castillo Fuentes, Laura, Gómez Hernández, Jonathan   +2 more
core  

Infosura en Equinos [PDF]

, 2011
La infosura en el caballo es una enfermedad que constituye una urgencia clínica de carácter grave, donde un alto porcentaje de los ejemplares que la cursan deben ser sometidos a eutanasia como producto de alteraciones tróficas inducidas por la patología,
García Liñeiro, Alberto, Godoy Pinto, Adolfo   +1 more
core   +3 more sources