Results 181 to 190 of about 2,066,107 (321)

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

IVUS Guided Ostial Lesion Preparation With Sequential Cutting Balloon Inflations and Stent Placement-The ORCAS Technique. [PDF]

Clin Case Rep
Ungureanu C, Cocoi M, Boukhris M, Colletti G, Jossart A, Trefois Q, Leibundgut G.   +6 more
europepmc   +1 more source

The Treatment of Lumbar Disk Lesions [PDF]

, 1950
James Cyriax
openalex   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Relationships Between Intra-Spinal Resting-State Functional Connectivity and Electrophysiology Following Spinal Cord Injury. [PDF]

Hum Brain Mapp
Yang PF, Reed JL, Sengupta A, Mishra A, Wang F, Gore JC, Chen LM.   +6 more
europepmc   +1 more source

A case of periarteritis nodosa with subcutaneous lesions and recovery [PDF]

, 1938
C. W. Vining
openalex   +1 more source

Quantitative Assessment of Upper Limb Ataxia Using a Virtual Reality‐Based Evaluation System

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebellar ataxia impairs coordination and balance, reducing quality of life. Conventional clinical scales, including the Scale for the Assessment and Rating of Ataxia (SARA) and the International Cooperative Ataxia Rating Scale (ICARS), are widely used to assess ataxia but are limited by subjectivity and inter‐rater variability ...
Masayuki Sato, Takayuki Abe, Sho Aoki, Setsuki Tsukagoshi, Yasushi Yuminaka, Yoshio Ikeda   +5 more
wiley   +1 more source

Magnetic Resonance Imaging Features of Spontaneous Subdural Hematoma Secondary to Necrotizing Encephalitis in a Dog. [PDF]

Vet Radiol Ultrasound
Kim E, Kim G, Seo K, Yoon J, Choi J.
europepmc   +1 more source

THE EFFECT OF HYPOTHALAMIC LESIONS ON THYROID FUNCTION IN THE DOG¹²

, 1955
William F. Ganong, Donald S. Fredrickson, David M. Hume   +2 more
openalex   +1 more source