Results 191 to 200 of about 1,344,206 (319)

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Cortical Lytic Lesion of the Proximal Tibia in an 8-Year-Old Child: A Pediatric Diagnostic Conundrum. [PDF]

J Orthop Case Rep
Dharmaraj K, Lourdes K, Choudhary M, Ganesh A, Kumar RS.   +4 more
europepmc   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Defining Activity-Based Subgroups in Multiple Sclerosis: A Review and Framework Proposal. [PDF]

Eur J Neurol
Lopez Manzano C, Rice CM, Tallantyre E, Cooper C, Wang H, Tomlinson E, Sadek A, Rao-Middleton A, Thom H, Whiting P.   +9 more
europepmc   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Lesion-specific design and oversizing as strategies for TAVI optimization: A patient-specific finite element study

Transcatheter aortic valve implantation (TAVI) is a revolutionary intervention for aortic stenosis, yet complications such as paravalvular leakage (PVL) and excessive tissue stress remain prevalent, particularly in anatomies with elliptical aortic roots.
Jia Wu (169990), Andy Gleadall (4378279), Simin Li (1252608), Jingwen Zhang (17128468), Zhihao Fan (9012419), Liguo Zhao (1250343), Ran He (207626), Dong Liu (115204)   +7 more
core  

Tremor Recurrence in MR-Guided Focused Ultrasound Thalamotomy for Essential Tremor: DBS vs. Re-lesion. [PDF]

Tremor Other Hyperkinet Mov (N Y)
Walker-Pizarro N, Chan JL, Yu J, Hilliard JD, Almeida L, Almeida L, Okun MS, Remz MA.   +7 more
europepmc   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Peripheral Giant Cell Granuloma Associated With Severe Periodontal Destruction in the Esthetic Region: A Case Report. [PDF]

Case Rep Dent
Burcu Yildirim K, Sayiner HH.
europepmc   +1 more source