Results 11 to 20 of about 1,781,133 (270)

Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis. [PDF]

, 2019
Chronic active and slowly expanding lesions with smouldering inflammation are neuropathological correlates of progressive multiple sclerosis pathology.
Arnold, Douglas L, Barkhof, Frederik, Belachew, Shibeshih, Bernasconi, Corrado, Elliott, Colm, Fecker, Julian, Hauser, Stephen L, Kappos, Ludwig, Model, Fabian, Wei, Wei, Wolinsky, Jerry S   +10 more
core   +1 more source

Mass spectrometry‐based extracellular vesicle micromolecule detection in cancer biomarker discovery: An overview of metabolomics and lipidomics

View, 2023
Extracellular vesicles (EVs) become one of the most important sources of cancer biomarkers during the past decade due to their wide distribution in body fluids and physiological stability.
Liyi Bai, Fanqin Bu, Xiangji Li, Shutian Zhang, Li Min   +4 more
doaj   +1 more source

Non-alcoholic fatty liver is associated with increased risk of irritable bowel syndrome: a prospective cohort study

BMC Medicine, 2022
Background The relationship between non-alcoholic fatty liver degree as well as non-alcoholic fatty liver disease (NAFLD) and irritable bowel syndrome (IBS) remains poorly understood.
Shanshan Wu, Changzheng Yuan, Zhirong Yang, Si Liu, Qian Zhang, Shutian Zhang, Shengtao Zhu   +6 more
doaj   +1 more source

Pan-cancer patterns of cuproptosis markers reveal biologically and clinically relevant cancer subtypes

Biomarker Research, 2023
Cuproptosis is a newly discovered type of cell death triggered by copper accumulation. Here we exhibited the genetic profiles of 10 cuproptosis-associated genes (CuAGs) across 21 cancer types.
Fanqin Bu, Xiangji Li, Yu Zhao, Liyi Bai, Shutian Zhang, Li Min   +5 more
doaj   +1 more source

Analysis of lesion localisation at colonoscopy: outcomes from a multi-centre U.K. study [PDF]

, 2016
Background: Colonoscopy is currently the gold standard for detection of colorectal lesions, but may be limited in anatomically localising lesions. This audit aimed to determine the accuracy of colonoscopy lesion localisation, any subsequent changes in
Anderson, John H., Bisset, Carly, Bryce, Adam S., Chisholm, Lindsey J., Diament, Robert H., Fountas, Spyridon, Griffiths, Ben, Horgan, Alan, Hung, Amy, Johnstone, Mark E., Khan, Khurram, Khine, Myo, Leitch, E. Fiona, Lockwood, Sonia, Mackay, Graham, McCarthy, Kathryn, McGregor, John R., McKee, Ruth F., Molloy, Richard, Moug, Susan, Renwick, Andrew, Saldanha, James D., Vella, Mark   +22 more
core   +2 more sources

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson, Giacomo Panozzo, Giorgio Boschi, Giuseppe Scarpa, Nicola Zemella, null null, Sandro Saviano, Stefania Miotto, Stefano Piermarocchi   +8 more
core   +1 more source

Large tumor suppressor kinase 2 overexpression attenuates 5-FU-resistance in colorectal cancer via activating the JNK-MIEF1-mitochondrial division pathway

Cancer Cell International, 2019
Background 5-Fluorouracil (5-FU) is a standard treatment for colorectal cancer, but most patients develop 5-FU resistance. Here, we conducted experiments to identify an effective approach to augment 5-FU-based treatment in colorectal cancer in vitro ...
Weilong Yao, Shengtao Zhu, Peng Li, Shutian Zhang   +3 more
doaj   +1 more source

Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]

, 2012
BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen, Dehghani, Faramarz, Ehrlich, Angela, Geisslinger, Gerd, Hobusch, Constance, Kallendrusch, Sonja, Koch, Marco, Nowicki, Marcin, Ziebell, Simone   +8 more
core   +3 more sources

Aphthous lesions

Oral Surgery, Oral Medicine, Oral Pathology, 1972
Oral Surgery, Oral Medicine, Oral Pathology 33 (1972) 407-416. doi:10.1016/0030-4220(72)90470-7 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:20:32 ; DOI:10.1016/0030-4220(72)90470-7 ; Page Range: 407 ...
College of Dentistry, University of Florida Gainesville, Fla., USA ( host institution ), Stanley, Harold R. ( author )   +1 more
openaire   +3 more sources

MGP Promotes Colon Cancer Proliferation by Activating the NF-κB Pathway through Upregulation of the Calcium Signaling Pathway

Molecular Therapy: Oncolytics, 2020
Matrix Gla protein (MGP), an extracellular matrix protein, is mainly associated with the inhibition of calcification in skeleton, coronary artery, and kidney, and more recently it has also been implicated in cancer.
Xueqing Li, Rui Wei, Mizhu Wang, Li Ma, Zheng Zhang, Lei Chen, Qingdong Guo, Shuilong Guo, Shengtao Zhu, Shutian Zhang, Li Min   +10 more
doaj   +1 more source