Results 21 to 30 of about 3,826,952 (368)

Mass spectrometry‐based extracellular vesicle micromolecule detection in cancer biomarker discovery: An overview of metabolomics and lipidomics

View, 2023
Extracellular vesicles (EVs) become one of the most important sources of cancer biomarkers during the past decade due to their wide distribution in body fluids and physiological stability.
Liyi Bai, Fanqin Bu, Xiangji Li, Shutian Zhang, Li Min   +4 more
doaj   +1 more source

Post-stroke deficit prediction from lesion and indirect structural and functional disconnection.

Brain : a journal of neurology, 2020
Behavioural deficits in stroke reflect both structural damage at the site of injury, and widespread network dysfunction caused by structural, functional, and metabolic disconnection.
A. Salvalaggio, Michele De Filippo De Grazia, M. Zorzi, M. Thiebaut de Schotten, M. Corbetta   +4 more
semanticscholar   +1 more source

Non-alcoholic fatty liver is associated with increased risk of irritable bowel syndrome: a prospective cohort study

BMC Medicine, 2022
Background The relationship between non-alcoholic fatty liver degree as well as non-alcoholic fatty liver disease (NAFLD) and irritable bowel syndrome (IBS) remains poorly understood.
Shanshan Wu, Changzheng Yuan, Zhirong Yang, Si Liu, Qian Zhang, Shutian Zhang, Shengtao Zhu   +6 more
doaj   +1 more source

Analysis of lesion localisation at colonoscopy: outcomes from a multi-centre U.K. study [PDF]

, 2016
Background: Colonoscopy is currently the gold standard for detection of colorectal lesions, but may be limited in anatomically localising lesions. This audit aimed to determine the accuracy of colonoscopy lesion localisation, any subsequent changes in
Anderson, John H., Bisset, Carly, Bryce, Adam S., Chisholm, Lindsey J., Diament, Robert H., Fountas, Spyridon, Griffiths, Ben, Horgan, Alan, Hung, Amy, Johnstone, Mark E., Khan, Khurram, Khine, Myo, Leitch, E. Fiona, Lockwood, Sonia, Mackay, Graham, McCarthy, Kathryn, McGregor, John R., McKee, Ruth F., Molloy, Richard, Moug, Susan, Renwick, Andrew, Saldanha, James D., Vella, Mark   +22 more
core   +2 more sources

DeepLesion: automated mining of large-scale lesion annotations and universal lesion detection with deep learning

Journal of Medical Imaging, 2018
. Extracting, harvesting, and building large-scale annotated radiological image datasets is a greatly important yet challenging problem. Meanwhile, vast amounts of clinical annotations have been collected and stored in hospitals’ picture archiving and ...
K. Yan, Xiaosong Wang, Le Lu, R. Summers
semanticscholar   +1 more source

The Generalized Contrast-to-Noise Ratio: A Formal Definition for Lesion Detectability

IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2019
In the last 30 years, the contrast-to-noise ratio (CNR) has been used to estimate the contrast and lesion detectability in ultrasound images. Recent studies have shown that the CNR cannot be used with modern beamformers, as dynamic range alterations can ...
Alfonso Rodriguez-Molares, O. M. Rindal, J. D’hooge, S. Måsøy, A. Austeng, M. L. Lediju Bell, H. Torp   +6 more
semanticscholar   +1 more source

Integrated Analysis Identifies Molecular Signatures and Specific Prognostic Factors for Different Gastric Cancer Subtypes

Translational Oncology, 2017
BACKGROUND: Gastric cancer (GC) is the fifth leading cause of cancer-related deaths worldwide. As an effective and easily performed method, microscopy-based Lauren classification has been widely accepted by gastrointestinal surgeons and pathologists for ...
Li Min, Yu Zhao, Shengtao Zhu, Xintao Qiu, Rui Cheng, Jie Xing, Linlin Shao, Shuilong Guo, Shutian Zhang   +8 more
doaj   +1 more source

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson, Giacomo Panozzo, Giorgio Boschi, Giuseppe Scarpa, Nicola Zemella, null null, Sandro Saviano, Stefania Miotto, Stefano Piermarocchi   +8 more
core   +1 more source

Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]

, 2012
BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen, Dehghani, Faramarz, Ehrlich, Angela, Geisslinger, Gerd, Hobusch, Constance, Kallendrusch, Sonja, Koch, Marco, Nowicki, Marcin, Ziebell, Simone   +8 more
core   +3 more sources

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]

, 2015
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L, Austin, Cecilia, Awad, Issam A, De Souza, Jorge Marcondes, Gallione, Carol J, Gunel, Murat, Lee, Connie, Marchuk, Douglas A, McDonald, David A, Mikati, Abdul Ghani, Min, Wang, Rebeiz, Tania, Rorrer, Autumn, Shenkar, Robert, Shi, Changbin, Stockton, Rebecca A, Zhang, Lingjiao   +16 more
core   +2 more sources