Results 21 to 30 of about 1,781,133 (270)

Exceptional aggressiveness of cerebral cavernous malformation disease associated with PDCD10 mutations. [PDF]

, 2015
PurposeThe phenotypic manifestations of cerebral cavernous malformation disease caused by rare PDCD10 mutations have not been systematically examined, and a mechanistic link to Rho kinase-mediated hyperpermeability, a potential therapeutic target, has ...
Akers, Amy L, Austin, Cecilia, Awad, Issam A, De Souza, Jorge Marcondes, Gallione, Carol J, Gunel, Murat, Lee, Connie, Marchuk, Douglas A, McDonald, David A, Mikati, Abdul Ghani, Min, Wang, Rebeiz, Tania, Rorrer, Autumn, Shenkar, Robert, Shi, Changbin, Stockton, Rebecca A, Zhang, Lingjiao   +16 more
core   +2 more sources

Evaluation of circulating small extracellular vesicles derived miRNAs as biomarkers of early colon cancer: a comparison with plasma total miRNAs

Journal of Extracellular Vesicles, 2019
Early diagnosis of colon cancer (CC) is clinically important, as it can significantly improve patients’ survival rate and quality of life. Although the potential role for small extracellular vesicles (sEVs) in early detection of many diseases has been ...
Li Min, Shengtao Zhu, Lei Chen, Xiang Liu, Rui Wei, Libo Zhao, Yuqing Yang, Zheng Zhang, Guanyi Kong, Peng Li, Shutian Zhang   +10 more
doaj   +1 more source

Integrated Analysis Identifies Molecular Signatures and Specific Prognostic Factors for Different Gastric Cancer Subtypes

Translational Oncology, 2017
BACKGROUND: Gastric cancer (GC) is the fifth leading cause of cancer-related deaths worldwide. As an effective and easily performed method, microscopy-based Lauren classification has been widely accepted by gastrointestinal surgeons and pathologists for ...
Li Min, Yu Zhao, Shengtao Zhu, Xintao Qiu, Rui Cheng, Jie Xing, Linlin Shao, Shuilong Guo, Shutian Zhang   +8 more
doaj   +1 more source

Naming and recognition of six foot lesions of sheep using written and pictorial information: a study of 809 English sheep farmers [PDF]

, 2008
In 2005, 3000 questionnaires were sent to a random sample of English sheep farmers from a list kept by the English Beef and Lamb Executive (EBLEX) to investigate whether farmers could correctly name six common foot lesions in sheep from a characteristic ...
Green, Laura E., Kaler, Jasmeet
core   +2 more sources

Brain networks under attack : robustness properties and the impact of lesions [PDF]

, 2016
A growing number of studies approach the brain as a complex network, the so-called ‘connectome’. Adopting this framework, we examine what types or extent of damage the brain can withstand—referred to as network ‘robustness’—and conversely, which kind of ...
Aerts, Hannelore, Caeyenberghs, Karen, Fias, Wim, Marinazzo, Daniele   +3 more
core   +2 more sources

Breast-Lesion Characterization using Textural Features of Quantitative Ultrasound Parametric Maps [PDF]

, 2017
© 2017 The Author(s). This study evaluated, for the first time, the efficacy of quantitative ultrasound (QUS) spectral parametric maps in conjunction with texture-analysis techniques to differentiate non-invasively benign versus malignant breast lesions.
A Ahmed, A Heindl, A König, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, A Sadeghi-Naini, AV Alvarenga, B Sigel, D Sengupta, E Feleppa, EJ Feleppa, EJ Feleppa, EJ Feleppa, EJ Feleppa, EJ Feleppa, F Davnall, FL Lizzi, FL Lizzi, FLL Lizzi, H Tadayyon, H Tadayyon, H Tadayyon, H Tadayyon, J Mamou, JPB O’Connor, K Polyak, KA Wear, KA Wear, KC Balaji, L Sannachi, LX Yao, M Vaidya, MJ Gerdes, ML Oelze, ML Oelze, ML Oelze, ML Oelze, ML Oelze, N Duric, N Sannomiya, R Natrajan, RJ Lavarello, RL Siegel, RM Haralick, S Chicklore, S Tan, T Cover, T Noritomi, TJ Larkin, V Goh, Y Labyed, Y Labyed, Y-Y Liao   +55 more
core   +2 more sources

Non-Thermal Plasma Jet-Treated Medium Induces Selective Cytotoxicity against Mycobacterium tuberculosis-Infected Macrophages

Biomedicines, 2022
Plasma-treated media (PTM) serve as an adjuvant therapy to postoperatively remove residual cancerous lesions. We speculated that PTM could selectively kill cells infected with Mycobacterium tuberculosis (Mtb) and remove postoperative residual tuberculous
Chae Bok Lee, Kang In Lee, Young Jae Kim, In Taek Jang, Sintayehu Kebede Gurmessa, Eun Ha Choi, Nagendra Kumar Kaushik, Hwa-Jung Kim   +7 more
doaj   +1 more source

Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis. [PDF]

, 2017
PURPOSE:Confocal adaptive optics scanning laser ophthalmoscope (AOSLO) images provide a sensitive measure of cone structure. However, the relationship between structural findings of diminished cone reflectivity and visual function is unclear.
Cunningham, Emmett T, Duncan, Jacque L, Foote, Katharina G, Gorin, Michael B, Lujan, Brandon J, Qin, Jia, Ratnam, Kavitha, Roorda, Austin, Tu, Joanna H, Tuten, William S   +9 more
core   +1 more source

Intracellular matrix Gla protein promotes tumor progression by activating JAK2/STAT5 signaling in gastric cancer

Molecular Oncology, 2020
Matrix Gla protein (MGP) has been widely reported as an extracellular matrix protein with abnormal expression in various types of cancer. However, the function of intracellular MGP in gastric cancer (GC) cells remains largely unknown.
Mizhu Wang, Lei Chen, Yu Chen, Rui Wei, Qingdong Guo, Shengquan Zhu, Shuilong Guo, Shengtao Zhu, Shutian Zhang, Li Min   +9 more
doaj   +1 more source

FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma

Molecular Oncology, 2019
FAM175B is a reported regulator of p53 and suppresses tumorigenesis in numerous types of cancer, but very little is known about its function in esophageal squamous cell carcinomas (ESCCs), almost 70% of which exhibit mutations in p53.
Yu Zhao, Yang Yu, Hengcun Li, Zheng Zhang, Shuilong Guo, Shengtao Zhu, Qingdong Guo, Peng Li, Li Min, Shutian Zhang   +9 more
doaj   +1 more source