Results 21 to 30 of about 12,297 (177)
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
Special Issue “Understanding Sports-Related Health Issues, 2nd Edition”
Sports-related health issues represent a complex and multifactorial phenomenon that extends far beyond the immediate occurrence of an injury or the onset of an illness [...]
Daniel Rojas-Valverde
doaj +1 more source
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka +7 more
wiley +1 more source
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Nivel de conocimientos sobre el tabaquismo y su relación con la cavidad bucal
Introducción: El tabaquismo es una enfermedad adictiva crónica la cual constituye la causa de muerte prevenible más importante en los países desarrollados y la de mayor morbilidad y mortalidad antes que cualquier otra enfermedad crónica (hipertensión ...
Liem Renda Valera +3 more
doaj
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Caracterización de lesiones en jugadores de fútbol de las categorías sub 19 y sub 20
El objetivo de esta investigación es caracterizar las lesiones de mayor incidencia en futbolistas. Se presenta un estudio de alcance descriptivo y diseño transversal, cuyos criterios de inclusión son: deportistas (hombres), que llevaran con el club más ...
Laura Elizabeth Castro-Jiménez +5 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Los accidentes de tránsito representan un problema de salud pública de gran magnitud a nivel mundial, siendo una de las principales causas de mortalidad y discapacidad, especialmente en países de ingresos bajos y medios.
Byron Oviedo-Bayas +3 more
doaj +1 more source

