Results 241 to 250 of about 32,400 (286)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

[Beyond the plaque: immunological implications of risk factors in atherosclerosis]. [PDF]

Arch Cardiol Mex
Aguilar-Villegas ÓR, Barragán-Los Santos J, Del Moral-Wong LE, Amezcua-Guerra LM, Aguirre-García MM.   +4 more
europepmc   +1 more source

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

Advanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang, Xuxi Chen, Hongying Quan, Rui Qian, Shuyu Gong, Qiurong He, Ying Gao, Ajia Axi, Manyu Zhao, Qin Zhang, Ling Zhang, Lijun Peng, Xin Sun, Ben Zhang, Yuqin Yao   +14 more
wiley   +1 more source

[Frailty and adverse outcomes in patients over 65 years old with acute coronary syndrome in a hospital cohort in Medellin, Colombia]. [PDF]

Arch Peru Cardiol Cir Cardiovasc
Navarro-Navajas A, Narvaéz-Orozco A, Aguirre-Acevedo DC, Pabón-De Ossa D, Angarita-Vasquez V, Ortiz-Uribe JC, Delgado-Restrepo JA, Senior-Sánchez JM.   +7 more
europepmc   +1 more source

[Colitis cystica profunda induced by radiation 27 years later. Case report]. [PDF]

Rev Med Inst Mex Seguro Soc
García-Acosta JG, Castañeda-Ángeles EG.   +1 more
europepmc   +1 more source

[Endoscopists in Training and the Use of <i>Over the Scope Clips</i> as First Line Treatment in Non-variceal Upper Gastrointestinal Bleeding]. [PDF]

Acta Gastroenterol Latinoam
Cabanas S, Pérez T, Mahler Spinelli MA, González ML, Ortiz Suarez P, Abecia Soria VH, Marcolongo MM.   +6 more
europepmc   +1 more source

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Vascular Lesions

Facial Plastic Surgery Clinics of North America, 2016
Classification of vascular lesions based of off the biological behavior has greatly facilitated more accurate diagnoses, optimally defined treatment plans, and better outcomes. Treatment of vascular lesions has taken a more conservative surgical approach with reliance on select medical treatment options, which has greatly reduced morbidity and ...
Keimun A, Slaughter, Tiffany, Chen, Edwin, Williams   +2 more
openaire   +4 more sources

Vascular Lesions

Facial Plastic Surgery Clinics of North America
Vascular lesions impact up to 5% of children and range in clinical impact from minor cutaneous aberrations to large masses impacting both form and function. Vascular lesions may be characterized as tumors or malformations. Establishing a clear diagnosis is imperative to understanding the natural history of a vascular lesion and developing a treatment ...
Matthew J, Urban, Edwin F, Williams
  +6 more sources

Vascular Lesions

Clinics in Plastic Surgery, 1993
Most cutaneous vascular abnormalities can be successfully, and in fact preferentially, treated with lasers. The field is evolving rapidly. It is important that the appropriate laser be used. In addition, many of the early references in this field are quite out of date.
B M, Achauer, V M, Vander Kam
openaire   +2 more sources