Results 131 to 140 of about 2,026,130 (318)
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
QJM: An International Journal of Medicine, 2020 T, Gailson, S, Pandit, S, Rathi
openaire +2 more sources
Oral soft tissue lesions: A guide to differential diagnosis Part II: Surface alterations [PDF]
able etiology and significance; their appropriate management relies on their accurate diagnosis. Considerable overlapping of the signs and symptoms produced by these diverse conditions poses significant problems for their diagnosis, which can be resolved
Nikitakis, Nikolaos G.
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Lacrimal fossa lesions: a review of 146 cases in Egypt [PDF]
, 2014 Mohammed A Eldesouky,1 Molham A Elbakary,1 Saly Sabik,1 Mohamed M Shareef2 1Oculoplastic Unit, Ophthalmology Department, Faculty of Medicine, Tanta University, 2Pathology Department, Faculty of Medicine, Tanta University, Tanta, Egypt Purpose: The ...
Elbakary MA +3 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Histological changes of endocervical polypoid lesions in women at reproductive age
Medical Journal of BabylonBackground: Endocervical polyps (ECP) are fragile benign protrusions commonly affecting 2%–5% of women during the reproductive age. Aim: This study aimed to identify the histopathological changes of clinically identified endocervical polypoid lesions ...
Muna Zuhair Al-Hamdany +1 more
doaj +1 more source