Results 101 to 110 of about 8,072,886 (297)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
More or Less Equal? English/Welsh resources for ages 11-16
, 2016 Bring your English and Welsh lessons to life by exploring how inequality and poverty affect the lives of young people in different parts of the world, including the UK. Created in partnership with Young Lives and with the support of subject associations,
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#NiUnaMenos: Not One Woman Less, Not One More Death! [PDF]
, 2016 On October 19, hundreds of thousands of women across Argentina [3] braved a torrential downpour to participate in two extraordinary protests: an unprecedented women’s strike and a massive demonstration against femicide (femicidio)—that is, the killing of
Tabbush, Constanza +1 more
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Journal of Public Interest CommunicationsSocial media platforms offer valuable tools for public administrators seeking to assess public sentiment on policy issues, especially in urban areas with diverse stakeholder interests.
Marco Castillo
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The Dual Nature of Choice: When Consumers Prefer Less to More
Economists typically assume that more choice is better, and consumers are more likely to purchase from a larger choice set. However, marketing and psychological studies show this is not always the case.
Norwood, F. Bailey, Lusk, Jayson L.
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, 2016 The natural history of PD produces a predominance of nonmotor complications in the later years that can often be more disabling than the motor complications due to their impact on quality of life.
Richard A. Walsh
core +1 more source
Less Is More, but Is More Less? [PDF]
Circulation: Cardiovascular Interventions, 2020 openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source