Results 81 to 90 of about 8,072,886 (297)
Less is more: a rationalization of daily labwork
Canadian Medical Education Journal, 2018 Routine daily phlebotomy can often act as a replacement for direct patient care. Some tests are necessary to gauge treatment response, however many are unnecessary and increase a patient’s risk of complications and can impede laboratory processing times.
Barry Chan +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Is less more? A preliminary investigation of the number of response categories in self-reported pain
, 2010 Karon F Cook1, David Cella2, Erin L Boespflug1, Dagmar Amtmann11Department of Rehabilitation Medicine, University of Washington, Seattle, WA; 2Department of Medical Social Sciences, Northwestern University, Feinberg School of Medicine, Chicago, IL ...
David Cella +3 more
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Making more from less. CEPS Commentary, 10 August 2016
, 2016 However regrettable Brexit may be, the EU needs to move forward. This is no time to be content with the status quo. Doing nothing will condemn the Union to decline.
Lannoo, Karel.
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
When less is more: the impact of macro and micro social media influencers’ disclosure
, 2020 There are growing discussions of social media influencers and their effectiveness in endorsing products. Further, recent policy regulations are requiring social media influencers to disclose sponsored content when using a form of native advertising. This
Kay, S, Mulcahy, R, Parkinson, J
core +1 more source
Afterword: Less is the New More
RegenerationThis afterword to the special issue discusses the author’s affective experiences with energy transition. The particular focus is the affective promise of electrification as a means to rupture the ecological emergency generated by today’s petroculture.
Dominic Boyer
doaj +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source