Results 241 to 250 of about 487,432 (309)

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Larvicidal and Ovicidal Effects of Methanol Extracts From Selected Ethiopian Medicinal Plants Against <i>Anopheles arabiensis</i> and <i>Aedes aegypti</i>. [PDF]

J Trop Med
Tesfaye L, Aklilu E, Tolossa K, Animut A.   +3 more
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Multitarget Acaricidal Activity of Essential Oils from <i>Alpinia zerumbet</i> and <i>Mesosphaerum suaveolens</i> Against <i>Tetranychus urticae</i>. [PDF]

Insects
Martins HPF, Silva GLD, Silva EPD, Rojas MOAI, Gonçalves FJT, Marques IS, Negreiros MVS, Morais VALL, Sousa FC, Cantanhede Filho AJ, Gomes BA, Rodrigues Filho E, França SM, Sousa AH, Lopes LM, Silva GN, Barbosa DRES.   +16 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Analysis of the threshold range of ROS concentration in winter rapeseed of the <i>Brassica napus</i> type. [PDF]

Front Plant Sci
Qi W, Sun W.
europepmc   +1 more source

Polar Lattice‐Distorted Motifs Enable Synergy of Local Polarization/Dipole Fields for Concurrent Glyphosate Wastewater Remediation and CO Evolution

Advanced Science, EarlyView.
Photocatalytic treatment of glyphosate herbicide in agricultural wastewater is achieved through the cooperative effect of the local polarization field and dipole field mediated by lattice‐distorted carbon nitride. Glyphosate is completely degraded via selective C─P bond cleavage with a CO evolution rate of 1166 µmol g−1 h−1.
Daoping Chen, Huan Liu, Tengyu Liu, Jie Li, Qizhi Luo, Yan Zhang, Shengkun Li, Hu Li   +7 more
wiley   +1 more source

Toxicity of ivermectin on multiple insecticide-resistant populations of Anopheles gambiae sensu lato, Aedes aegypti, and Culex mosquitoes. [PDF]

Parasit Vectors
Obuobi D, Amlalo GK, Wieser A, Froeschl G, Kudom AA.   +4 more
europepmc   +1 more source

ATP burst is the dominant driver of antibiotic lethality in <i>Mycobacterium smegmatis</i>. [PDF]

Elife
Lodhiya T, Palande A, Veeram A, Larrouy-Maumus GJ, Beste DJV, Mukherjee R.   +5 more
europepmc   +1 more source

Lethal and Sublethal Effects of the Novel cis-Nitromethylene Neonicotinoid Cycloxaprid on the Green Peach Aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae). [PDF]

Toxics
Zhu J, Wang L, Cui Z, Huang W, Wang Q, Wang W, Yang Q, Rui C, Cui L.   +8 more
europepmc   +1 more source