Results 111 to 120 of about 17,950,531 (342)

State-level variation drives wolf management in the northwestern United States

Environmental Research: Ecology
Recovered and recovering carnivore populations in Europe and North America can pose risks to some human livelihoods like livestock ranching. These risks can motivate wildlife managers to lethally remove carnivores—decisions that are often controversial ...
Leandra Merz, Nicolas T Bergmann, Casey L Brown, Jeff Vance Martin, Chloe B Wardropper, Jeremy T Bruskotter, Neil H Carter   +6 more
doaj   +1 more source

Lethal Dose of Calcium Bentonite in Wistar Rats

, 2021
Background: Calcium bentonite is a type of clay produced by a devitrification of volcanic ash which is often used as a traditional medicine to absorb toxins and waste products of metabolism.
Adnan, Adria, Dwika Audiyananda, Yuwono, Hendro Sudjono, Hendro Sudjono Yuwono, Audiyananda, Dwika, Adria Adnan   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

SEADETECT: Multi-sensor Cetacean Collision Prevention in the Pelagos Area of the Mediterranean Sea [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
The Pelagos Sanctuary for Mediterranean Marine Mammals is a designated marine protected area in the north-western Mediterranean, encompassing waters between the Côte d’Azur (France), the Ligurian and Tuscan coasts (Italy), and Monaco ...
A. Schilling, B. Rumes, S. Panigada, R. Jan, T. Folegot, V. Carrier, A. Dumoulin, D. Van Hamme, G. Marquis-Laisné, A. Rouhan, O. Langrand   +10 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Lethal perinatal hypophosphatasia caused by a novel compound heterozygous mutation: a case report

BMC Pediatrics, 2019
Background Hypophosphatasia (HPP) is a rare hereditary disorder characterized by defective bone and tooth mineralization and deficiency of tissue non-specific alkaline phosphatase (TNAP) activity.
Fengdan Yu, Junyi Wang, Xiaojing Xu
doaj   +1 more source

Mechanisms of ferroptosis

Cellular and Molecular Life Sciences, 2016
Ferroptosis is a non-apoptotic form of cell death that can be triggered by small molecules or conditions that inhibit glutathione biosynthesis or the glutathione-dependent antioxidant enzyme glutathione peroxidase 4 (GPX4). This lethal process is defined
J. Cao, S. Dixon
semanticscholar   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Prognostic value of heart rhythm variability in patients with chronic heart failure (three-year investigation) [PDF]

Саратовский научно-медицинский журнал, 2011
Aim: to estimate prognostic value of indicators of heart rhythm variability (HRV) in patients with chronic heart failure (CHF) within three years. Materials and methods: A total of 110 patients aged 55,2±6,5 years with CHF experienced Q-wave myocardial ...
Kosheleva N.A.
doaj  

Investigation of the anti-inflammatory, hypoglycemic activity and median lethal dose (LD50) level of limonene in mice and rats [PDF]

, 2018
The aim of this study is to investigate the anti-inflammatory, hypoglycemic activity and median lethal lose (LD50) level of limonene mice and rats. Lethal dose levels were investigated using the probit analysis method.
Özbek, Hanefi, Hanefi Özbek, Betül Sever Yılmaz, Sever Yılmaz, Betül   +3 more
core   +1 more source