Results 81 to 90 of about 17,950,531 (342)
Correlation of ferritin, D-dimer, and CRP with disease severity and outcome in COVID-19 patients
The European Chemistry and Biotechnology JournalHigher levels of ferritin were associated with severe forms of COVID-19 disease. Given the above, our goal was to investigate the associations between ferritin levels within COVID-19-infected individuals from the Adjara population (Georgia).
Ia Murvanidze +15 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Fast-SL: an efficient algorithm to identify synthetic lethal sets in metabolic networks [PDF]
Bioinform., 2014 MOTIVATION Synthetic lethal sets are sets of reactions/genes where only the simultaneous removal of all reactions/genes in the set abolishes growth of an organism.
Aditya Pratapa +2 more
semanticscholar +1 more source
Lethal Concentrations of Copper and Zinc for Young Atlantic Salmon
, 1964 The toxicity of copper and zinc sulphates to immature Atlantic salmon (Salmo salar L.) was tested in soft water.The relation between concentration of metal and survival-time could be fitted by a straight line when logarithms were used.
J. B. Sprague
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Lethal copper concentration levels for Clarias gariepinus (Burchell, 1822) @ a preliminary study
Koedoe: African Protected Area Conservation and Science, 1993 Lethal copper concentrations were determined for both adult and juvenile Clarias gariepinus at representative mean summer and winter temperatures. Fish were exposed to copper for 96 hours in an experimental system and mortalities monitored.
Marinda Van der Merwe +2 more
doaj
Does mutational robustness inhibit extinction by lethal mutagenesis in viral populations? [PDF]
PLoS Computational Biology, 2010 Lethal mutagenesis is a promising new antiviral therapy that kills a virus by raising its mutation rate. One potential shortcoming of lethal mutagenesis is that viruses may resist the treatment by evolving genomes with increased robustness to mutations ...
Eamon B O'Dea +2 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Antimicrobial Resistance and Infection Control, 2017 Background Antimicrobial violet-blue light in the region of 405 nm is emerging as an alternative technology for hospital decontamination and clinical treatment.
Rachael M. Tomb +4 more
doaj +1 more source
The police use of less-lethal weapons [PDF]
, 2007 When police officers find themselves facing a violent individual or superior numbers, the level of potential danger is increased significantly. As a result, the police officer must quickly disable the attacker(s) and improve the likelihood of control. In
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