Results 131 to 140 of about 1,466 (243)

Bio‐guided fractionation of (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai   +3 more
wiley   +1 more source

Little penguins select more isolated nest boxes for breeding, but lay date influences breeding success

open access: yesThe Journal of Wildlife Management, EarlyView.
We determined that more isolated and possibly older nest boxes were selected by little penguins for breeding at Pōhatu/Flea Bay, New Zealand. However, breeding success was influenced by lay date in comparison to nest box characteristics. These findings inform immediate conservation recommendations regarding nest box design and placement.
Georgia S. M. Gwatkin   +5 more
wiley   +1 more source

Synergistic Effects of Salinization and Artificial Root Exudates on Soil Phosphatase Activity in Coastal Soil

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Coastal soil salinization from rising seawater levels has adverse impacts on soil function, seed germination, and plant growth. Root exudates play a key role in supporting microbial activity, nutrient cycling, and plant health, yet little is known about the combined effects of salinization and the addition of artificial root exudates (AREs) on
Nicolina Lentine   +4 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

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