Results 31 to 40 of about 1,106 (233)

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

Hepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen, Yu‐Chia Su, Yee‐Ern Or, Chin‐Fu Cheng, John T. Kung   +4 more
wiley   +1 more source

Promising primers for detection of phytoplasma causing coconut lethal yellowing disease in Mozambique [PDF]

Phytoparasitica, 2018
جوز الهند هو أحد المحاصيل النقدية الرئيسية في موزمبيق، التي احتلت المركز الثاني بعد تنزانيا في إنتاج جوز الهند في أفريقيا. تأثر إنتاج جوز الهند بشكل كبير بحدوث أوبئة مرض اصفرار جوز الهند المميت (CLYD) المدمرة، مما قلل بشكل كبير من غلة جوز الهند. تستخدم أعراض CLYD الناجمة عن عدوى البلازما النباتية، أي إسقاط الفاكهة قبل الأوان، ونخر الإزهار والاصفرار ...
M. O. M. Mazivele, Valter Nuno Antόnio Nuaila, M. Durante, Mauro Colombo, Elisa Taviani   +4 more
openaire   +2 more sources

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Sorologia e sobrevivência do vírus do amarelo letal do mamoeiro Serology and surviving characteristics of Papaya lethal yellowing virus

Revista Ciência Agronômica, 2010
O vírus do amarelo letal do mamoeiro (Papaya lethal yellowing virus, PLYV) é responsável por uma das principais doenças do mamoeiro (Carica papaya) no Nordeste brasileiro.
Ana Lúcia Lopes do Nascimento, José Albersio de Araujo Lima, Aline Kelly Queiroz do Nascimento, Maria de Fátima Barros Gonçalves   +3 more
doaj   +1 more source

Pest categorisation of Haplaxius crudus

EFSA Journal, 2020
The EFSA Panel on Plant Health performed a pest categorisation of the planthopper Haplaxius crudus (Hemiptera: Cixiidae) for the EU. This species occurs from south‐eastern USA to Northern Brazil and on many Caribbean islands.
EFSA Panel on Plant Health (PLH), Claude Bragard, Katharina Dehnen‐Schmutz, Francesco Di Serio, Paolo Gonthier, Marie‐Agnès Jacques, Josep Anton Jaques Miret, Annemarie Fejer Justesen, Christer Sven Magnusson, Panagiotis Milonas, Juan A Navas‐Cortes, Stephen Parnell, Roel Potting, Philippe Lucien Reignault, Hans‐Hermann Thulke, Wopke Van der Werf, Antonio Vicent Civera, Jonathan Yuen, Lucia Zappalà, Ewelina Czwienczek, Virág Kertész, Franz Streissl, Alan MacLeod   +22 more
doaj   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal, Milan Patra, Rianita Mondal, Shubhasis Haldar   +3 more
wiley   +1 more source

Search for alternate hosts of the coconut Cape Saint Paul Wilt Disease pathogen

Oléagineux, Corps gras, Lipides, 2009
Lethal Yellowing disease locally called Cape Saint Paul wilt disease (CSPWD) is the bane of the coconut industry in Ghana and is caused by a phytoplasma.
Yankey Egya Ndede, Pilet Fabian, Quaicoe Robert Nketsia, Dery Sylvester Kuuna, Dollet Michel, Dzogbefia Victoria Pearl   +5 more
doaj   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Phytoplasma and phytoplasma diseases: a review of recent research

Phytopathologia Mediterranea, 2010
Numerous yellows-type diseases of plants have been associated with wall-less prokaryote pathogens – phytoplasma over the last 40 years. These pathogens cannot be grown in axenic culture so that advances in their study are mainly achieved by molecular ...
A. Bertaccini, B. Duduk
doaj   +1 more source