Results 231 to 240 of about 316,536 (262)

Violence, city size and geographical isolation in African cities. [PDF]

Nat Commun
Prieto-Curiel R, Menezes R.
europepmc   +1 more source

Dual‐Targeting Cuproptosis and Mitophagy via a Flavopiridol‐Copper Nanoplatform Potentiates Immunotherapy Against Uveal Melanoma

Advanced Science, EarlyView.
This study develops a GSH‐responsive nanoplatform, NP@Fla‐Cu, to co‐activate cuproptosis and excessive mitophagy in uveal melanoma. The nanoplatform enhances tumor‐specific copper delivery, depletes antioxidant defenses, and remodels the tumor immune microenvironment.
Hong Ren, Zhihong Deng, Sheng Lu, Jing Zhang, Wenbin Liu, Jia Tan   +5 more
wiley   +1 more source

Assembling the puzzle of antimicrobial resistance in staphylococcal biofilms. [PDF]

Emerg Microbes Infect
Nguyen T, McGiffin D, Lou B, Sun Y, Qian C, Kostoulias X, Zhang W, Peleg AY, Qu Y.   +8 more
europepmc   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

Nationwide epidemiological analysis of surgically treated upper limb vascular trauma over 16 years in Brazil. [PDF]

Einstein (Sao Paulo)
Ceratti MM, Sorbello CCJ, Portela FSO, Silva MFAD, Teivelis MP, Wolosker N.   +5 more
europepmc   +1 more source

Xylazine exacerbates fentanyl-induced respiratory depression and prevents rescue by naloxone in mice. [PDF]

Psychopharmacology (Berl)
Watkins JM, Hahn R, Dempsey M, Hohmann AG.   +3 more
europepmc   +1 more source

Persistent Gaps in the Ultimate Mechanisms of Antimicrobial-Induced Bacterial Killing. [PDF]

Antibiotics (Basel)
Nath A, Rodríguez-Rojas A.
europepmc   +1 more source

Twinfilin modulates tissue contractility through uncapping of capping protein in C. elegans. [PDF]

Development
Saini A, Kreizman S, Towsif E, Martinez-Lopez J, Zielonka IM, Nitzan A, Rudnick L, Shekhar S, Zaidel-Bar R.   +8 more
europepmc   +1 more source

Improving the sex-specificity of a conditional female lethal system for genetic biocontrol of the New World screwworm, Cochliomyia hominivorax. [PDF]

Sci Rep
Lowman AV, Arp AP, Sagel A, Patil AA, Quintero G, Vasquez M, Arias AD, Martinez A, Scott MJ.   +8 more
europepmc   +1 more source