Results 21 to 30 of about 315,540 (261)
Туберкулез и болезни лёгких, 2021 The objective of the study: in Tomsk Region, to establish the frequency of multiple drug resistance (MDR) of mycobacterium tuberculosis (MBT) in new tuberculosis patients with the reference to their HIV status and to assess their treatment outcomes ...
O. V. Filinyuk +5 more
doaj +1 more source
Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy [PDF]
, 2014 Phosphatase and tensin homolog (PTEN) loss is associated with genomic instability. APE1 is a key player in DNA base excision repair (BER) and an emerging drug target in cancer.
Allinson +49 more
core +2 more sources
The Association Between Dyslipidemia and Lethality of Suicide Attempts: A Case-Control Study
Frontiers in Psychiatry, 2019 Evidence supports the existence of an association between dyslipidemia, psychiatric disorders, and suicide risk due to the effects of altered lipid profiles on serotoninergic neuron membranes. The aim of this study was to investigate the differences in c-
Andrea Aguglia +15 more
doaj +1 more source
Российский журнал гериатрической медицины, 2020 Hip fractures are severe and life-threatening injuries with huge social, medical and economic consequences and a high mortality rate. The article is devoted to the organization of medical care in older patients group who received a hip fracture due to ...
M. V. Belov +3 more
doaj +1 more source
The structure and feature of polytrauma in children of Barnaul
Travmatologiâ i Ortopediâ Rossii, 2013 Analysis of fatal polytrauma in children in Barnaul over the period of 11 years, study of medical records of polytrauma patients brought in to hospital and medicolegal autopsy data from the cases of fatal polytrauma in children.
V. V. Timofeev, A. V. Bondarenko
doaj +1 more source
A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers. [PDF]
, 2016 mTOR inhibition has emerged as a promising strategy for head and neck squamous cell carcinomas (HNSCC) treatment. However, most targeted therapies ultimately develop resistance due to the activation of adaptive survival signaling mechanisms limiting the ...
Amornphimoltham, Panomwat +10 more
core +1 more source
Prediction of lethal and synthetically lethal knock-outs in regulatory networks
, 2013 The complex interactions involved in regulation of a cell's function are captured by its interaction graph. More often than not, detailed knowledge about enhancing or suppressive regulatory influences and cooperative effects is lacking and merely the ...
A Inger +28 more
core +1 more source
Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. [PDF]
, 2011 : Virus outbreaks have been found to be related to the concentration of a new class of genomic peptides, Replikins^1^. The eight genes of H5N1 influenza virus were analyzed for the distribution of Replikin Counts (number Replikins /100 amino acids) in 2 ...
Elenore S. Bogoch, Samuel Bogoch
core +2 more sources
Journal of Education, Health and Sport, 2022 The problem of gunshot wounds treatment is one of the urgent and incompletely resolved issues of modern surgery. Diagnosis of gunshot wounds is currently not efficient enough.
I. Lurin +4 more
doaj +1 more source
Clinical-epidemiologic characteristic of insults in Tomsk
Бюллетень сибирской медицины, 2006 Epidemiologic indices of brain insult using register method based upon recommendation of National Association on insults fight are studied. Morbidity, mortality and lethality from insults is shown taking as an example an open population of Kirovski ...
T. N. Nikolayeva +2 more
doaj +1 more source