Results 51 to 60 of about 202,850 (314)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Clinical Differences Between Single and Multiple Suicide Attempters, Suicide Ideators, and Non-suicidal Inpatients

Frontiers in Psychiatry, 2020
Single suicide attempters (SSAs) and multiple suicide attempters (MSAs) represent distinct subgroups of individuals with specific risk factors and clinical characteristics. This retrospective study on a sample of 397 adult psychiatric inpatients analyzed
Isabella Berardelli, Alberto Forte, Marco Innamorati, Benedetta Imbastaro, Benedetta Montalbani, Salvatore Sarubbi, Gabriele Pasquale De Luca, Martina Mastrangelo, Gaia Anibaldi, Elena Rogante, David Lester, Denise Erbuto, Gianluca Serafini, Mario Amore, Maurizio Pompili   +14 more
doaj   +1 more source

Lethality of Atad3 deficient mice.

, 2013
Lethality of Atad3 deficient mice.
Waldemar Kolanus (249413), Tobias Goller (286987), Wolfgang Voos (263793), Ursula K. Seibold (286989), Elisabeth Kremmer (17351)   +4 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Lethal effects of aqueous and alcoholic extracts of nettle (Urtica dioica) on nymphs of Linguatula serrata under in vitro conditions [PDF]

تحقیقات دامپزشکی و فرآورده‌های بیولوژیک
Introduction: Linguatula serrata, commonly known as the tongue worm, is a zoonotic parasite belonging to the order Pentastomida. Its nymphal stage accumulates in the internal tissues of intermediate hosts such as ruminants, causing pathological lesions ...
Nasser Hajipour, Yousef Panahi
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

Frontiers in Cell and Developmental Biology, 2020
The serine/threonine protein phosphatase 2A (PP2A) is a master regulator of the complex cellular signaling that occurs during all stages of mammalian development.
Nikita Panicker, Nikita Panicker, Melody Coutman, Melody Coutman, Charley Lawlor-O’Neill, Charley Lawlor-O’Neill, Richard G. S. Kahl, Richard G. S. Kahl, Séverine Roselli, Séverine Roselli, Nicole M. Verrills, Nicole M. Verrills   +11 more
doaj   +1 more source

Overdominant lethals as part of the conifer embryo lethal system [PDF]

Heredity, 2003
In pines, self-pollination rates can be as high as 34% yet only 5% of viable seed is a product of self-fertilization. This decline in selfed seed viability is the consequence of post-fertilization exclusion mechanisms operating via the embryo lethal system.
C G, Williams, L D, Auckland, M M, Reynolds, K A, Leach   +3 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

THE EFFECT OF LITHIUM ON ACUTE TOXICITY OF CHLORPROMAZINE IN MICE

Acta Medica Iranica, 1996
The effects of chronic administration of lithium, on acute toxicity of chlorpromazine (CPZ) in male albino mice was studied and the LDSO values were determined from dose-probit curves.
Dehpour, A.R., Samini M. Rahimsalehi, V.   +3 more
doaj