Results 41 to 50 of about 4,366,484 (267)

Determinants of harassment in online multiplayer games [PDF]

open access: yes, 2017
Objective. Online multiplayer games allow large numbers of participants to play simultaneously online. Unfortunately, this has also given rise to new forms of harassment and abuse.
De Letter, Jolien   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Honouring of the Legio Chief Physician L. Hortensius Paulinus

open access: yesBelleten, 2016
An inscription dated to the beginning of the 3rd century AD, and found within the city limits of Antiocheia in 2011, honors the legion Chief Physician L.
Abdurrahman Uzunaslan
doaj   +1 more source

Medium and long-term thermal coal contract embedded reparations from the perspective of an evolutionary game

open access: yesGlobal Energy Interconnection, 2022
Coal-fired electricity enterprises are caught in the dilemma of relative fixed prices and rising costs under the scenario of decarbonization. Meanwhile, soaring market-oriented coal pricing results in coal enterprises’ increasing defaults on thermal coal
Yalin Chena   +3 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Building Bonds And Breaking News: Exploring Male Journalists’ Personal Relationship Challenges

open access: yesInformasi
Workplace conditions significantly impact journalists' work-life balance and psychological well-being. This study explores male journalists' challenges in maintaining personal relationships outside of work via a phenomenological approach using purposive ...
Sheila May Balagan   +3 more
doaj   +1 more source

Shakespeare\u27s Pangrammatic Sonnet [PDF]

open access: yes, 2006
Among Shakespeare\u27s 154 sonnets, is there one that contains every letter of the alphabet? The letter Z occurs in 14 sonnets, the letter Q in 44, the letter X in 43, the letter J in 50, and the letter K in 151.
Eckler, A. Ross
core   +1 more source

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