Results 41 to 50 of about 4,422,154 (275)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
Fontes Linguae Vasconum, 2011 Artikuluak hiru zati ditu; lehenean Wentworth Webster euskalariak jaso zituen hiru gutunen berri ematen da, hirurak beste euskalari batzuek idatziak, Luis Luciano Bonapartek, Antoine Thomson d’Abbadíe eta aita Fidel Fitak idatziak hain zuzen ere ...
Ricardo Urrizola
doaj
« J’ay esté bien aise d’aprendre que vous soyez content du caractère de Mr Verrier »
Bulletin du Centre de Recherche du Château de Versailles, 2016 Between 1724 and 1745, Étienne Verrier, King’s Engineer, worked for the glory of France in the American colonies, constructing the Fortress of Louisbourg on the Isle Royale.
Sandrine Chabre
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Reviewers in 2009-2010 (Volumes 6 & 7) [PDF]
Reviewers in 2009-2010 (Volumes 6 & 7) As editors of Migration Letters, we are very grateful to the following colleagues for their reviews and recommendations.Migration Letters ...
Migration Letters
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick +14 more
wiley +1 more source
“O you little lovable best friend”: Writing Friendship in the Age of Enlightenment
De Musica Disserenda, 2020 This article examines the various discursive strands converging within the cult of friendship in mid-eighteenth-century German culture. Following Christian Fürchtegott Gellert’s “Vier und zwanzigste Moralische Vorlesung” (Twenty-fourth Moral Lecture), it
Tobias Heinrich
doaj +1 more source