His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source
Correction: Yao et al. Genome Selection for Fleece Traits in Inner Mongolia Cashmere Goats Based on GWAS Prior Marker Information. <i>Animals</i> 2025, <i>15</i>, 3184. [PDF]
Yao H +12 more
europepmc +1 more source
Time‐Efficient and Informatic‐Skill‐Light Gap‐Filling for Telomere‐to‐Telomere Genome Assembly
The paper introduces a novel auxiliary software toolbox GapSuite, consisting of two tools Gap‐Aid and Gap‐Graph, which guides users to fill gaps in chromosome‐level genome assembly using sequence‐extension‐based and assembly‐graph‐based strategies. The two tools enable users with limited informatics expertise to efficiently complete gap‐filling on ...
Dong Xu +8 more
wiley +1 more source
Erratum: [Corrigendum] p53 positively regulates the expression of cancer stem cell marker CD133 in HCT116 colon cancer cells. [PDF]
Chen X +7 more
europepmc +1 more source
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao +14 more
wiley +1 more source
[Retracted] Upregulation of cervical carcinoma expressed PCNA regulatory long non-coding RNA promotes esophageal squamous cell carcinoma progression. [PDF]
Wang X +5 more
europepmc +1 more source
Genetic Diagnosis and Discovery Enabled by Large Language Models
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu +25 more
wiley +1 more source
[Retracted] Tunicamycin inhibits progression of glioma cells through downregulation of the MEG-3-regulated wnt/β-catenin signaling pathway. [PDF]
Li X, Xue L, Peng Q.
europepmc +1 more source

