Leucoaraiosis, nigrostriatal denervation and motor symptoms in Parkinson's disease. [PDF]
Leucoaraiosis is associated with motor symptoms in otherwise normal older adults. Comorbid leucoaraiosis is predicted to contribute also to motor features in Parkinson's disease but previous studies of white matter changes in Parkinson's disease show variable results.
Roger L Albin +2 more
exaly +5 more sources
Association study of TREM2 polymorphism rs75932628 with leucoaraiosis or Parkinson's disease in the Han Chinese population [PDF]
Objectives The previously reported functional mutation rs75932628-T (p.R47H) in the triggering receptor expressed on myeloid cells 2 (TREM2) is a genetic risk factor for Alzheimer's disease, Parkinson's disease (PD) and frontotemporal dementia, in European populations.
Qing Lin, Xingkai An, Chi-Meng Tzeng
exaly +5 more sources
Multimodal imaging findings in normal-appearing white matter of leucoaraiosis: a review. [PDF]
Leucoaraiosis (LA), also referred to as white matter hyperintensities (WMHs), are usually seen as patchy or confluent hyperintense areas on T2-weighted or fluid-attenuated inversion recovery MRI in the elderly. It is often asymptomatic in its early stages, yet its persistent evolution to more advanced stages may lead to substantial neurological ...
Zhong G, Lou M.
europepmc +4 more sources
Dementia with leucoaraiosis and dural arteriovenous malformation: clinical and PET case study. [PDF]
A case of rapidly progressive dementia with diffuse leucoaraiosis on CT was attributable to a supratentorial dural arteriovenous malformation. Positron emission tomography (PET) showed low cerebral blood flow and high oxygen extraction ratio throughout the cerebral hemispheres indicating a state of chronic haemodynamic compromise which could predispose
P Nencini
exaly +3 more sources
The impact of leucoaraiosis on neurological function recovery in elderly patients with acute cerebral infarction: Clinical study involving 279 Chinese patients [PDF]
Objective To explore the link between leucoaraiosis and recovery of neurological function in elderly patients with acute cerebral infarction. Methods The study included elderly patients, hospitalized with acute cerebral infarction ...
Yong-hua Huang
exaly +3 more sources
Myotonic Dystrophy‐1 Complicated by Factor‐V (Leiden) Mutation
Objectives. Presence of a factor‐V Leiden mutation in a patient with myotonic dystrophy type 1 (DM1) has been reported only once. Here we report the second DM1 patient carrying a factor‐V mutation who died from long‐term complications of this mutation. Case Report.
Josef Finsterer +2 more
wiley +1 more source
The pathogenesis of cerebral small-vessel disease (SVD) is incompletely understood. Endothelial dysfunction has been implicated and may result in increased blood-brain barrier (BBB) permeability with leakage of blood constituents into the vessel wall and white matter.
Topakian, R +3 more
openaire +3 more sources
LEUCOARAIOSIS. ASPECTOS FISIOPATOLÓGICOS Y DIAGNÓSTICO POR IMAGEN
RESUMEN Introducción: El concepto de Leucoaraiosis, entidad relacionada con la enfermedad de pequeños vasos, hipertensión arterial y envejecimiento poblacional, surge a raíz de la introducción de nuevas modalidades de diagnóstico por imagen como la Tomografía Computarizada y la imagen por Resonancia Magnética.
Sonia Virgen Ramírez Navarro +3 more
openaire +2 more sources
[Leucoaraiosis: correlation of arterial hypertension and lacunar infarct (study of 80 patients)].
We studied 80 patients with lacunar strokes in the attempt to find a relation between lacunar strokes, arterial hypertension and leucoaraiosis. Leucoaraiosis was found in 47 patients (58,75%) on CT-scan. Our findings emphasize that arterial hypertension is the most important risk factor of leucoaraiosis (p less than 0.003); but we did not find a ...
L G, Lazzarino, A, Nicolai, F, Valassi
openaire +1 more source
The importance of interdisciplinary research. [PDF]
Widimsky P, Stetkarova I, Tousek P.
europepmc +1 more source

