Analysis of Risk Factors for Leukoaraiosis: A Multicenter Retrospective Study [PDF]
Brain and BehaviorBackground and Aim Leukoaraiosis is a common imaging marker of cerebral small vessel disease. There is now increasing evidence shows the relationship between leukoaraiosis and cognitive impairment, high risk of death after stroke.
Lingqi Sun +5 more
doaj +3 more sources
Segmentation of Leukoaraiosis on Noncontrast Head CT Using CT‐MRI Paired Data Without Human Annotation [PDF]
Brain and BehaviorObjective Evaluating leukoaraiosis (LA) on CT is challenging due to its low contrast and similarity to parenchymal gliosis. We developed and validated a deep learning algorithm for LA segmentation using CT‐MRIFLAIR paired data from a multicenter Korean ...
Wi‐Sun Ryu +9 more
doaj +3 more sources
Claudin-1 and Claudin-3 as Molecular Regulators of Myelination in Leukoaraiosis Patients [PDF]
Clinics, 2021 OBJECTIVES: Leukoaraiosis is described as white matter lesions that are associated with cognitive dysfunction, neurodegenerative disorders, etc. Myelin depletion is a salient pathological feature of, and the loss of oligodendrocytes is one of the most ...
Yan Chen +4 more
doaj +3 more sources
Parietal and occipital leukoaraiosis due to cerebral ischaemic lesions decrease the driving safety performance of healthy older adults [PDF]
Scientific Reports, 2022 Leukoaraiosis, a common ischaemic lesion diagnosed using magnetic resonance imaging (MRI), can influence driving safety performance (DSP). Most older drivers with leukoaraiosis are unaware of their affliction.
Hikaru Oba +3 more
doaj +2 more sources
Essence of ADC Values in Leukoaraiosis Imaging and Association of Leukoaraiosis with Cognitive Dysfunction [PDF]
International Journal of Anatomy Radiology and Surgery, 2017 Introduction: Leukoaraiosis is a common cerebral white matter disease identified radiologically as discrete focal or diffuse patchy bilateral hypodense on computed tomography and hyperintense on T2 weighted Resonance Imaging.
Sivakami Rathinam, Ragini Singh
doaj +2 more sources
Leukoaraiosis and Stroke [PDF]
Stroke, 2010 Leukoaraiosis is a common finding in stroke patients and has been strongly associated with risk of incident stroke and dementia. Leukoaraiosis may also be an independent predictor of stroke outcomes. There is increasing evidence from neuroimaging to support the concept that some leukoaraiosis is caused by white matter infarcts, which may be ...
Eric E Smith
exaly +3 more sources
Pathogenesis of Leukoaraiosis [PDF]
Stroke, 1997 Background Changes in the cerebral hemispheric white matter, detectable with increasing frequency by modern neuroimaging methods, are associated with aging and conceivably may contribute to the development of specific cognitive deficits.
Leonardo Pantoni
exaly +5 more sources
Correlates of telomere length shortening in peripheral leukocytes of HIV-infected individuals and association with leukoaraiosis. [PDF]
PLoS ONE, 2019 Telomere length (TL) is a marker of cellular and biological aging. Human immunodeficiency virus (HIV) infection has been reported to be associated with short TLs, which suggests that accelerated biological aging occurs in some cellular compartments of ...
Rumi Minami +2 more
doaj +2 more sources
Vascular Dysfunction in Leukoaraiosis [PDF]
American Journal of Neuroradiology, 2016 The pathogenesis of leukoaraiosis has long been debated. This work addresses a less well-studied mechanism, cerebrovascular reactivity, which could play a leading role in the pathogenesis of this disease. Our aim was to evaluate blood flow dysregulation and its relation to leukoaraiosis.Cerebrovascular reactivity, the change in the blood oxygen level ...
K. Sam +10 more
openaire +3 more sources
Hypertriglyceridemia Is Associated with Reduced Leukoaraiosis Severity in Patients with a Small Vessel Stroke [PDF]
Behavioural Neurology, 2018 Intracranial hemorrhage or microbleeds and leukoaraiosis have an overlap in biology. Hyperlipidemia may reduce the risk of ICH or cerebral microbleeds; studies focusing on the relationship between different lipid profiles and severity of periventricular ...
Daqiang Ke +4 more
doaj +2 more sources