Results 21 to 30 of about 5,152 (164)

Mediating roles of leukoaraiosis and infarcts in the effects of unilateral carotid artery stenosis on cognition

Frontiers in Aging Neuroscience, 2022
Background and objectivesLeukoaraiosis and infarcts are common in patients with carotid artery stenosis (CAS), and CAS severity, leukoaraiosis and infarcts all have been implicated in cognitive impairments.
Kuo-Lun Huang, Kuo-Lun Huang, Ting-Yu Chang, Ting-Yu Chang, Yi-Ming Wu, Yi-Ming Wu, Yeu-Jhy Chang, Yeu-Jhy Chang, Hsiu-Chuan Wu, Hsiu-Chuan Wu, Chi-Hung Liu, Chi-Hung Liu, Tsong-Hai Lee, Tsong-Hai Lee, Meng-Yang Ho, Meng-Yang Ho, Meng-Yang Ho   +16 more
doaj   +1 more source

Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study. [PDF]

, 2013
Cerebral small vessel disease (SVD) is a common cause of vascular cognitive impairment. A number of disease features can be assessed on MRI including lacunar infarcts, T2 lesion volume, brain atrophy, and cerebral microbleeds.
Lawrence, AJ, Barrick, Thomas R., Lawrence Andrew J., Barrick Thomas R., Andrew J Lawrence, Robin G Morris, MacKinnon, Andrew D., Hugh S. Markus, Thomas R Barrick, Bhavini Patel, Robin G. Morris, MacKinnon, AD, Bhavini Patel (405150), Barrick, TR, Philip M. Rich (405153), Markus, HS, Andrew D. MacKinnon, Rich, PM, Thomas R. Barrick (405154), Thomas R. Barrick, Hugh S Markus, Lawrence, Andrew J.; id_orcid, Patel, B, Andrew J. Lawrence, MacKinnon Andrew D., Rich, Philip M., Hugh S. Markus (366687), Andrew J. Lawrence (292444), Robin G. Morris (405151), Morris, RG, Patel Bhavini, Morris Robin G., Morris, Robin G., Andrew D MacKinnon, Rich Philip M., Patel, Bhavini, Philip M Rich, Andrew D. MacKinnon (405152), Markus Hugh S., Philip M. Rich, Markus, Hugh S.   +40 more
core   +2 more sources

Aggressive blood pressure reduction is not associated with decreased perfusion in leukoaraiosis regions in acute intracerebral hemorrhage patients.

PLoS ONE, 2019
Leukoaraiosis regions may be more vulnerable to decreases in cerebral perfusion. We aimed to assess perfusion in leukoaraiosis regions in acute intracerebral hemorrhage (ICH) patients.
Mahesh Kate, Laura Gioia, Thomas Jeerakathil, Michael D Hill, Bronwen Gould, Rebecca McCourt, Dar Dowlatshahi, Shelagh Coutts, Jayme Kosior, Andrew Demchuk, Brian Buck, Kenneth Butcher   +11 more
doaj   +1 more source

Leukoaraiosis predicts hidden global functioning impairment in nondisabled older people: The LADIS (Leukoaraiosis and Disability in the Elderly) study

OBJECTIVES: To determine whether leukoaraiosis severity is independently associated with differences in global functioning in nondisabled elderly patients.
Chabriat H, Wallin A, Inzitari D, Barkhof F, Basile AM, Pracucci G, Erkinjuntti T, Visser MC, Poggesi A, O'Brien J, Schmidt R, Ferro JM, Hennerici M, Waldemar G, Pantoni L, Wahlund L-O   +15 more
core   +5 more sources

Vascular deaths in elderly neurological patients with leukoaraiosis [PDF]

, 1997
Objectives-The prognostic significance of leukoaraiosis is still not completely elucidated. The objective was to examine survival and causes of death among elderly neurological patients with leukoaraiosis.
Pracucci, G, Inzitari, D, Pantoni, L, Marranci, M L, Cadelo, M   +4 more
core   +1 more source

Topologic Efficiency Abnormalities of the Connectome in Asymptomatic Patients with Leukoaraiosis

Brain Sciences, 2022
Leukoaraiosis (LA) is commonly found in aging healthy people but its pathophysiological mechanism is not entirely known. Furthermore, there is still a lack of effective pathological biomarkers that can be used to identify the early stage of LA.
Shun Yao, Hong-Ying Zhang, Ren Wang, Ding-Sheng Cheng, Jing Ye   +4 more
doaj   +1 more source

Dynamic functional connections in leukoaraiosis patients without cognitive impairment: A pilot study

Frontiers in Aging Neuroscience, 2022
PurposeLeukoaraiosis (LA) is a major public issue that affects elderly adults. However, the underlying neuropathological mechanism of LA without cognitive impairment requires examination.
Xingru Xu, Yu-Chen Chen, Xindao Yin, Taosheng Zuo, Guangkui Feng, Kaixi Xu   +5 more
doaj   +1 more source

Leukoaraiosis

, 2008
Leukoaraiosis describes diffuse white matter abnormalities on CT or MR brain scans, often seen in the normal elderly and in association with vascular risk factors such as hypertension, or in the context of cognitive impairment. The term was introduced to
O'Sullivan, Mike, O'Sullivan, Michael
core   +1 more source

Leukoaraiosis as a Promising Biomarker of Stroke Recurrence among Stroke Survivors: A Systematic Review

Neurology International, 2023
Stroke is the leading cause of functional disability worldwide, with increasing prevalence in adults. Given the considerable negative impact on patients’ quality of life and the financial burden on their families and society, it is essential to provide ...
Theofanis Dimaras, Ermis Merkouris, Dimitrios Tsiptsios, Foteini Christidi, Anastasia Sousanidou, Ilias Orgianelis, Efthymia Polatidou, Iordanis Kamenidis, Stella Karatzetzou, Aimilios Gkantzios, Christos Ntatsis, Christos Kokkotis, Sofia Retsidou, Maria Aristidou, Maria Karageorgopoulou, Evlampia A. Psatha, Nikolaos Aggelousis, Konstantinos Vadikolias   +17 more
doaj   +1 more source

Leukoaraiosis and Stroke Outcome

, 2002
We Studied the Influence of Leukoaraiosis on the Prognosis of Stroke for the First Year after Onset. Three Hundred and Seventy Consecutive Stroke Subjects Were Observed for 1 Year.
Czlonkowska, Anna, Podgorska, Anna, Hier, Daniel B., Pytlewski, Andrzej   +3 more
core   +1 more source