Results 41 to 50 of about 3,801 (177)
Roles of Microglia in Cerebral Small Vessel Disease
CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.Chronic cerebral hypoperfusion triggers microglial activation in cerebral small vessel disease (CSVD). Activated microglia drive neuroinflammation, oxidative stress, and blood–brain barrier disruption, leading to white matter hyperintensities, enlarged perivascular spaces, and other neuroimaging features.
Chenyang Jin +7 more
wiley +1 more source
Red Blood Cell Distribution Width Is Associated with Severity of Leukoaraiosis.
PLoS ONE, 2016 Red blood cell distribution width (RDW) is one of the routine hematologic parameters reported in the complete blood count test, which has been recognized as strong prognostic marker for various medical conditions, especially cardiovascular disease.
Han-Bin Lee +7 more
doaj +1 more source
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.Abstract Vascular cognitive impairment (VCI), including vascular dementia (VaD), encompasses a spectrum of cognitive deficits resulting from cerebrovascular pathology, ranging from mild impairment to dementia. As the second leading cause of dementia worldwide, VCI remains a major therapeutic challenge.
Doan‐Khanh Tran +3 more
wiley +1 more source
BMC Neurology, 2020 Background To investigate the relationships between blood pressure (BP) circadian rhythms and acute cerebral infarction (ACI), silent cerebral infarction (SCI) and the severity of leukoaraiosis in hypertensive patients.
Kang Yang +7 more
doaj +1 more source
Decreased Number of Mitochondria in Leukoaraiosis [PDF]
Archives of Medical Research, 2015 Leukoaraiosis (LA), one of the most frequent causes of an age-associated cognitive decline, can be associated with a poor quality of life, leading overall to far-reaching public health problems. Chronic hypoxia of the white matter of the brain may be a factor triggering this entity.
Szolnoki Zoltán +7 more
openaire +3 more sources
Инновационная медицина КубаниObjective: To investigate metabolite changes in patients with leukoaraiosis employing multivoxel magnetic resonance spectroscopy (MRS) with the focus on periventricular white matter and explicate the biochemical alterations associated with leukoaraiosis ...
Ragitha Ramesh +3 more
doaj +1 more source
Early MRI imaging and follow-up study in cerebral amyloid angiopathy
Open Medicine, 2021 To study the imaging features of leukoaraiosis (LA) and hemorrhage in cerebral amyloid angiopathy (CAA) patients.
Zhang Shan-chun +8 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.Abstract INTRODUCTION There is a critical need to identify risk factors of Alzheimer's disease and related dementias (ADRD). METHODS We included 1227 participants (mean age [standard deviation]: 74.1 [7.9] years) from the Multi‐Ethnic Study of Atherosclerosis with brain MRI scans.
Cameron J. Reimer +12 more
wiley +1 more source
The Egyptian Journal of Radiology and Nuclear Medicine, 2018 Background: MRI is an essential tool for diagnosing multiple sclerosis; however, overlap with nonspecific white matter lesions still exists. The central vein sign as detected by MR susceptibility weighted imaging has been proposed to improve the ...
Shirin H. Al-Zandi +2 more
doaj +1 more source
European Journal of Neurology, Volume 33, Issue 5, May 2026.Functional stroke‐like episodes are increasingly recognised as stroke mimics. In a study of 25 cases who underwent hyperacute multimodal CT, patients were younger than their counterparts with acute ischaemic strokes and often had a psychiatric and functional disorder background.
Filipa Bastos +5 more
wiley +1 more source