Results 61 to 70 of about 3,801 (177)

Differential risk factors for lacunar stroke depending on the MRI (white and red) subtypes of microangiopathy. [PDF]

PLoS ONE, 2012
BACKGROUND: Leukoaraiosis and cerebral microbleeds (CMB), which represent cerebral microangiopathy, commonly coexist in patients with acute lacunar stroke.
Jae-Hyun Park, Sookyung Ryoo, Suk Jae Kim, Gyeong-Moon Kim, Chin-Sang Chung, Kwang Ho Lee, Oh Young Bang   +6 more
doaj   +1 more source

Leukoaraiosis and Ischemia [PDF]

Stroke, 2006
See related article, pages 1391–1398 Although Alois Alzheimer had described in 1902 a baffling extensive and severe degeneration of the cerebral white matter (misnamed Binswanger disease), over half a century of regular examination of brains by histological techniques failed to recognize the common occurrence of bilateral, patchy or confluent, white ...
openaire   +1 more source

A DTI study of leukoaraiosis and the differential diagnosis between leukoaraiosis and acute lacunar infarction [PDF]

CNS Neuroscience & Therapeutics, 2019
No abstract ...
Zhao, De-Qiang, Wang, Zhan-Wen, Cheng, Ying, Yuan, Zhen, Rene, Frédérique, Liu, Haoyi, Pliss, Artem, Luan, Ping   +7 more
openaire   +3 more sources

The Relationship Between Hippocampal Cerebrovascular Reactivity and Brain Structure in Older Age

Human Brain Mapping, Volume 47, Issue 3, 15 February 2026.
Lower hippocampal cerebrovascular reactivity was associated with smaller grey matter volume and reduced white matter microstructural integrity in the corpus callosum, internal capsule, and fornix cross‐sectionally, and with longitudinal decline in the corpus callosum, internal capsule, and cingulum.
Congxiyu Wang, Lucy Jobbins, Graham Reid, Georgina Hobden, Raihaan Patel, Clare E. Mackay, Klaus P. Ebmeier, Joana Pinto, Daniel Bulte, Mika Kivimäki, Archana Singh‐Manoux, Sana Suri   +11 more
wiley   +1 more source

Binswanger's disease and quantitative fractional anisotropy Doença de Binswanger e anisotropia fracionada quantitativa

Arquivos de Neuro-Psiquiatria, 2009
OBJECTIVE: To study the integrity of the white matter in Binswanger's disease (BD) patients with quantitative fractional anisotropy (DTI-FA). METHOD: Controls (12) and patients with BD (12) were included.
Eliasz Engelhardt, Denise Madeira Moreira, Gilberto Sousa Alves, Maria Elisa Oliveira Lanna, Carlos Eduardo de Oliveira Alves, Letice Ericeira-Valente, Felipe Kenji Sudo, Jerson Laks   +7 more
doaj   +1 more source

Hainan Longevity Model, Senile Degeneration, Cognitive Disability and Healthy Longevity

AGING MEDICINE, Volume 9, Issue 1, Page 67-81, February 2026.
Investigating centenarians who exemplify healthy longevity can aid in formulating preventive strategies aimed at achieving health and extending lifespan in the context of population aging. Hainan longevity model (HLM) plays key roles in promoting healthy longevity and provides scientific evidence for achieving healthy longevity in the older population.
Shihui Fu, Jiacai Lin, Qianshuo Liu, Lianbo Gao, Zhirui Li, Feng Lin, Leixing Xie, Xiong Liu, Wenkai Xiao, Qiwei Zhu, Fan Wang, Jin Zheng, Yali Zhao, Xiaolei Chen, Yao Yao, Long Feng   +15 more
wiley   +1 more source

Hypertriglyceridemia Is Associated with Reduced Leukoaraiosis Severity in Patients with a Small Vessel Stroke

Behavioural Neurology, 2018
Intracranial hemorrhage or microbleeds and leukoaraiosis have an overlap in biology. Hyperlipidemia may reduce the risk of ICH or cerebral microbleeds; studies focusing on the relationship between different lipid profiles and severity of periventricular ...
Daqiang Ke, Feng Zhou, Hui Liang, Yang Xu, Haiyan Lou   +4 more
doaj   +1 more source

The association of uric acid with leukoaraiosis [PDF]

Journal of International Medical Research, 2016
Objective To explore the possible correlation between uric acid levels and leukoaraiosis (LA). Methods This cross-sectional study enrolled patients who presented with some neurological discomfort (e.g.
Li, Jun-Jing, Huang, Yin-Hui, Lin, You-Yu, Li, Mi-Mi, Chen, Ya-Fang, Cai, Ruo-Wei   +5 more
openaire   +2 more sources

Global Research Trends and Hotspots in Cerebral Small Vessel Disease‐Related Cognitive Impairment: A Bibliometric Analysis (2001–2024)

Brain and Behavior, Volume 16, Issue 1, January 2026.
This bibliometric study systematically analyzed 1074 publications in the field of CSVD‐CI from 2001 to 2024. The research reveals three evolutionary phases and identifies four core research clusters: pathophysiological mechanisms, neuroimaging biomarkers, clinical assessment, and therapeutic interventions.
Kuihua Wang, Xiaohui Ji, Hui Li, Xiaoyang Wang, Xiaoyue Jin, YanJun Lin, Qiao Wang, Haizhen Xu, Jianxin Ye, Xiaoping Cui, Yonghui Liang   +10 more
wiley   +1 more source

Race/Ethnicity Disparities in the Association of CXCL9 and CCL2 with the Burden of White Matter Disease: The Northern Manhattan Study [PDF]

Alzheimers Dement
Abstract Background Pro‐inflammatory cytokines and chemokines play a critical role in neurodegenerative diseases. However, the specific immunological pathways driving such pathology, and whether these are influenced by race or ethnicity, remain unclear.
Shahrestani M, Gardener H, Veledar E, Elkind M, Gutierrez J, Rundek T, Wright C.   +6 more
europepmc   +2 more sources