Results 81 to 90 of about 8,824 (256)

Global Research Trends and Hotspots in Cerebral Small Vessel Disease‐Related Cognitive Impairment: A Bibliometric Analysis (2001–2024)

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
This bibliometric study systematically analyzed 1074 publications in the field of CSVD‐CI from 2001 to 2024. The research reveals three evolutionary phases and identifies four core research clusters: pathophysiological mechanisms, neuroimaging biomarkers, clinical assessment, and therapeutic interventions.
Kuihua Wang   +10 more
wiley   +1 more source

Pilot Investigation: Older Adults With Atrial Fibrillation Demonstrate Greater Brain Leukoaraiosis in Infracortical and Deep Regions Relative to Non-Atrial Fibrillation Peers

open access: yesFrontiers in Aging Neuroscience, 2020
BackgroundThis pilot study explored differences in distribution of white matter hyperintensities (called leukoaraiosis; LA) in older adults (mean age = 67 years) with atrial fibrillation (AF) vs.
Margaret E. Wiggins   +9 more
doaj   +1 more source

Prediction of Impaired Performance in Trail Making Test in MCI Patients With Small Vessel Disease Using DTI Data [PDF]

open access: yes, 2016
Mild cognitive impairment (MCI) is a common condition in patients with diffuse hyperintensities of cerebral white matter (WM) in T2-weighted magnetic resonance images and cerebral small vessel disease (SVD).
Citi, Luca   +9 more
core   +2 more sources

Leukoaraiosis and Ischemia [PDF]

open access: yesStroke, 2006
See related article, pages 1391–1398 Although Alois Alzheimer had described in 1902 a baffling extensive and severe degeneration of the cerebral white matter (misnamed Binswanger disease), over half a century of regular examination of brains by histological techniques failed to recognize the common occurrence of bilateral, patchy or confluent, white ...
openaire   +1 more source

A Novel and Simple Score to Predict Embolic or Atherosclerotic Middle Cerebral Artery Occlusion Before Mechanical Thrombectomy: AHOC Score

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This study developed and validated the novel AHOC score, a simple pre‐thrombectomy tool for predicting stroke etiology (embolism vs. intracranial atherosclerosis) in acute middle cerebral artery occlusion. This score integrates four key clinical/imaging variables—atrial fibrillation, hyperdense artery sign, stenosis/occlusion in other arteries, and ...
Hudie Zhang   +17 more
wiley   +1 more source

Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study

open access: yesBMC Medical Genomics, 2009
Background Subcortical white matter hyperintensity on magnetic resonance imaging (MRI) of the brain, referred to as leukoaraiosis, is associated with increased risk of stroke and dementia.
Jack Clifford R   +8 more
doaj   +1 more source

Risk factors of dilated Virchow-Robin spaces are different in various brain regions. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND AND PURPOSE: Few studies have reported on the risk factors of dilated Virchow-Robin Spaces (dVRS) in large samples of ischemic stroke patients.
Changqing Zhang   +16 more
doaj   +1 more source

Validation Conditions for the Use of Diffusion Tensor Imaging for Neuroprognosis: A Clinical and Technical Review

open access: yesInternational Journal of Biomedical Imaging, Volume 2026, Issue 1, 2026.
In the growing field of neuroprognosis in intensive care patients, the use of diffusion tensor imaging (DTI) MRI to quantify white matter integrity is particularly promising, with solid demonstrations for predicting outcomes in cardiac arrest and severe traumatic brain injury.
Pierre Simeone   +14 more
wiley   +1 more source

Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2014
Aims: The aim is to study the prevalence and possible relationship of apathy and leukoaraiosis in cases of cognitive impairment of varying severity in Spain.
Carmen María Sarabia-Cobo   +4 more
doaj   +1 more source

ADC mapping of the aging frontal lobes in mild cognitive impairment [PDF]

open access: yes, 2018
Normal aging, leukoaraiosis (LA) and vascular disease particularly involve the human frontal lobes. We decided to investigate a population of elderly patients referred for neuroimaging because of progressive minor cognitive deficits but no dementia. They
Assal, F.   +11 more
core  

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