Results 91 to 100 of about 8,824 (256)

Binswanger's disease and quantitative fractional anisotropy Doença de Binswanger e anisotropia fracionada quantitativa

Arquivos de Neuro-Psiquiatria, 2009
OBJECTIVE: To study the integrity of the white matter in Binswanger's disease (BD) patients with quantitative fractional anisotropy (DTI-FA). METHOD: Controls (12) and patients with BD (12) were included.
Eliasz Engelhardt, Denise Madeira Moreira, Gilberto Sousa Alves, Maria Elisa Oliveira Lanna, Carlos Eduardo de Oliveira Alves, Letice Ericeira-Valente, Felipe Kenji Sudo, Jerson Laks   +7 more
doaj   +1 more source

Chronic small vessel disease affects clinical outcome in patients with acute striatocapsular stroke [PDF]

, 2011
Background: Recovery from stroke is presumed to be a function of a cerebral network. Chronic small vessel disease (SVD) has been shown to disrupt this network’s integrity and has been proposed as a predictor of poor outcome after stroke.
Bäzner, Hansjörg, Held, Valentin, Hennerici, Michael G., Szabo, Kristina   +3 more
core   +1 more source

Autoimmune and paraneoplastic encephalitis–associated neuronal autoantibodies with serial EEG in adults with unexplained new‐onset seizures or worsening epilepsy

Epilepsia Open, Volume 10, Issue 6, Page 1978-1989, December 2025.
Abstract Objective Unexplained seizures or worsening epilepsy in adult patients may be associated with specific neuronal or onconeuronal antibodies. We propose that comprehensive antibody testing is beneficial for adults with new‐onset seizures or aggravated epilepsy without a predetermined etiology.
Chang‐Yu Edward Cheng, Jen‐Jen Su, Chiehyu Shen, I‐Ting Lin, Pin‐Yu Chen, Tun Jao   +5 more
wiley   +1 more source

Heritability of Leukoaraiosis in Hypertensive Sibships [PDF]

Hypertension, 2004
Ischemic damage to the subcortical white matter of the brain, referred to as leukoaraiosis, is a frequent complication of hypertension-related microvascular disease and contributes to the risk of stroke and vascular dementia. A large genetic contribution to this late-life form of target organ damage was suggested by a study of elderly male
Stephen T, Turner, Clifford R, Jack, Myriam, Fornage, Thomas H, Mosley, Eric, Boerwinkle, Mariza, de Andrade   +5 more
openaire   +2 more sources

Shared genes and pathways in dementia: Insights from genome‐wide association studies

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract Dementia, a collective term for neurodegenerative disorders marked by cognitive decline, affects millions worldwide, and is expected to rise significantly in prevalence. Genome‐wide association studies (GWASs), as highlighted in this review, have revolutionized our understanding of dementia by identifying contributing genetic loci and pathways,
Kyle J. Loi, Noah Radtke, Chloe Kiriluk, Mohamed H. Noureldein, Eva L. Feldman, Kelly M. Bakulski, Kevin S. Chen   +6 more
wiley   +1 more source

Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery. [PDF]

, 2020
Background Impaired neurological function affects 85% to 90% of cardiac arrest (CA) survivors. Pulsatile blood flow may play an important role in neurological recovery after CA.
Akbari, Yama, Bazrafkan, Afsheen, Choi, Bernard, Crouzet, Christian, Lee, Donald, Tromberg, Bruce J, Wilson, Robert H   +6 more
core   +1 more source

Frequency of Microvascular Pathology and Hippocampal Atrophy on Magnetic Resonance Imaging in a Community Study of Alzheimer's Disease with Blood‐Based Biomarkers

Annals of Neurology, Volume 98, Issue 5, Page 1027-1043, November 2025.
Objective Blood‐based biomarkers for Alzheimer's disease (AD), representing antemortem indicators of AD pathophysiology, have greatly improved the accuracy of diagnosis. However, these biomarkers may not capture a frequent coincident pathology, such as cerebrovascular disease.
Tamil Iniyan Gunasekaran, Danurys Sanchez, Dolly Reyes‐Dumeyer, Rabel Ventura, Clarissa Morales, Mohamad Alshikho, Annie J. Lee, Rafael A. Lantigua, Yian Gu, Lawrence S. Honig, Badri N. Vardarajan, Adam M. Brickman, Richard Mayeux   +12 more
wiley   +1 more source

Predictors of highly prevalent brain ischemia in intracerebral hemorrhage [PDF]

, 2012
Objective: This study was undertaken to determine the prevalence, characteristics, risk factors, and temporal profile of concurrent ischemic lesions in patients with acute primary intracerebral hemorrhage (ICH).
Anderson, Fazekas, Goldstein, Greenberg, Hill, Kidwell, Kimberly, Menon, Prabhakaran, Rosand, Rosso, Siddique, Wijman, Zazulia   +13 more
core   +1 more source

COL4A1‐Related Leukoencephalopathy and Microangiopathy: A Case Series of Two Palestinian Siblings

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT We report two Palestinian siblings with a pathogenic COL4A1 mutation, presenting with congenital cataracts, seizures, developmental delay, and antenatal intracerebral hemorrhages. Despite sharing the same genetic variant, they exhibited striking phenotypic variability.
Thkra Meshal, Amal M. Shawabka, Kareem lbraheem, Rosol Iwaiwi, Nissreen E. Thafer, Jinan H. Afana, Ahmad G. Hammouri, Osama Atawneh   +7 more
wiley   +1 more source

Thrombolysis and thrombectomy for acute ischaemic stroke [PDF]

, 2017
The likelihood of disability-free recovery after acute ischemic stroke is significantly improved by reperfusion either by intravenous thrombolytic drug treatment or with endovascular mechanical thrombectomy in selected cases.
El Tawil, Salwa, Muir, Keith W.
core   +1 more source