Isolated Subtle Neurological Abnormalities in Mild Cognitive Impairment Types [PDF]
, 2020 Background: Isolated, subtle neurological abnormalities (ISNA) are commonly seen in aging and have been related to cerebral small vessel disease (SVD) and subcortical atrophy in neurologically and cognitively healthy aging subjects.
Azzarello, Delia +7 more
core +1 more source
Neural basis of motor symptoms in Alzheimer's disease: role of regional tau burden and cognition
Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.Abstract INTRODUCTION With accumulating evidence that motor manifestations in Alzheimer's disease (AD) may emerge from AD pathology independent of other copathologies, we investigated the neural basis of motor dysfunction under the amyloid/tau/neurodegeneration (ATN) framework.
Han Kyu Na +8 more
wiley +1 more source
Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]
, 2019 Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S. +7 more
core +2 more sources
Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri +10 more
wiley +1 more source
Determination of optimum combination of voxel size and b-value for brain diffusion tensor imaging [PDF]
, 2017 Optimum combination of voxel size resolution and b-value for whole brain imaging has been determined. Data images were acquired using a 1.5T magnetic resonance imaging (MRI) system (GE Signa HDxt).
Enrico Magosso, +4 more
core +1 more source
Combining physical training with transcranial direct current stimulation to improve gait in Parkinson's disease: a pilot randomized controlled study [PDF]
, 2014 OBJECTIVE: To improve gait and balance in patients with Parkinson's disease by combining anodal transcranial direct current stimulation with physical training.
Allum, JH +4 more
core +1 more source
Editorial Comment—The Progression of Leukoaraiosis [PDF]
Stroke, 2003 Leukoaraiosis (LA), the presence of rarefaction of the white matter originally described on CT1 but now more commonly recognized on MRI, was originally largely ignored as an inconsequential finding seen in association with cerebrovascular disease. More recently, it has become clear that LA impairs cognition.2 When LA is sufficiently prominent to be ...
openaire +2 more sources
Author response for "Leukoaraiosis and acute ischemic stroke"
, 2021 Xiaojia Tang +6 more
openalex +1 more source
Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease. [PDF]
, 2017 OBJECTIVE: To determine whether MRI markers, including diffusion tensor imaging (DTI), can predict cognitive decline and dementia in patients with cerebral small vessel disease (SVD).
Andrew D. Mackinnon +13 more
core +1 more source
Leukoaraiosis Mediates the Association of Total White Blood Cell Count With Post-Stroke Cognitive Impairment [PDF]
, 2022 Wanying Shan +6 more
openalex +1 more source