Results 31 to 40 of about 8,824 (256)

Leukoaraiosis and Gray Matter Volume Alteration in Older Adults: The PROOF Study

Frontiers in Neuroscience, 2022
Background and Purpose: Leukoaraiosis, also called white matter hyperintensities (WMH), is frequently encountered in the brain of older adults. During aging, gray matter structure is also highly affected.
Sébastien Celle, Sébastien Celle, Claire Boutet, Claire Boutet, Cédric Annweiler, Cédric Annweiler, Romain Ceresetti, Romain Ceresetti, Vincent Pichot, Vincent Pichot, Jean-Claude Barthélémy, Jean-Claude Barthélémy, Frédéric Roche, Frédéric Roche   +13 more
doaj   +1 more source

Longitudinal study on low-dose aspirin versus placebo administration in silent brain infarcts: the silence study [PDF]

, 2018
Background. We investigated low-dose aspirin (ASA) efficacy and safety in subjects with silent brain infarcts (SBIs) in preventing new cerebrovascular (CVD) events as well as cognitive impairment. Methods.
Altieri, Marta, Bastianello, Stefano, Carlucci, Giovanna, Cavallini, Anna, Coppola, Cristiana, Di Clemente, Laura, Di Giuseppe, Matteo, Di Piero, Vittorio, Federico, Francesco, Inzitari, Domenico, Lucivero, Vincenzo, Maestrini, Ilaria, Marini, Carmine, Mezzapesa, Domenico Maria, Micieli, Giuseppe, Pantano, Patrizia, Paolino, Isabella, Parnetti, Lucilla, Peducci, Maria, Persico, Alessandra, Prontera, Maria Pia, Provinciali, Leandro, Raz, Eytan, Russo, Tommasina, Sarchielli, Paola, Serrati, Carlo, Silvestrini, Mauro, Vicenzini, Edoardo, Zat, Carla   +28 more
core   +1 more source

The Clinical Utility of Leukoaraiosis as a Prognostic Indicator in Ischemic Stroke Patients

Neurology International, 2022
Stroke constitutes a major cause of functional disability with increasing prevalence among adult individuals. Thus, it is of great importance for both clinicians and stroke survivors to be provided with a timely and accurate prognostication of functional
Foteini Christidi, Dimitrios Tsiptsios, Anastasia Sousanidou, Stefanos Karamanidis, Sofia Kitmeridou, Stella Karatzetzou, Souzana Aitsidou, Konstantinos Tsamakis, Evlampia A. Psatha, Efstratios Karavasilis, Christos Kokkotis, Nikolaos Aggelousis, Konstantinos Vadikolias   +12 more
doaj   +1 more source

Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease [PDF]

, 2016
Funded by Parkinson's UK National Institute for Health Research (NIHR) DeNDRoN network NIHR Newcastle Biomedical Research Unit Newcastle University NIHR funded Biomedical Research Centre in CambridgePeer reviewedPublisher ...
Bajaj, Nin, Barker, Roger A, Ben-Shlomo, Yoav, Burn, David J, Grosset, Donald G, Grosset, Katherine A, Hardy, John, Lawton, Michael A, Malek, Naveed, Marrinan, Sarah L, Morris, Huw R, PRoBaND Clinical Consortium, Swallow, Diane M A, Williams, Nigel M, Wood, Nicholas   +14 more
core   +5 more sources

Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]

, 2019
No abstract ...
Berry, C, Ford, TJ, Hainsworth, AH, Kaski, JC, Pereira, AC, Sidik, N, Touyz, RM   +6 more
core   +2 more sources

Clinical characteristics of unknown symptom onset stroke patients with and without diffusion-weighted imaging and fluid-attenuated inversion recovery mismatch [PDF]

, 2017
Background: Diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) mismatch was suggested to identify stroke patients with unknown time of symptom onset likely to be within the time window for thrombolysis. Aims: We aimed
Boutitie, Florent, Cheng, Bastian, Cho, Tae-Hee, Ebinger, Martin, Endres, Matthias, Fiebach, Jochen B., Fiehler, Jens, Ford, Ian, Galinovic, Ivana, Gerloff, Christian, Lemmens, Robin, Muir, Keith W., Nighoghossian, Norbert, Pedraza, Salvador, Puig, Josep, Roy, Pascal, Simonsen, Claus Z., Thijs, Vincent, Thomalla, Götz   +18 more
core   +2 more sources

Clinical characterization of symptomatic microangiopathic brain lesions

Frontiers in Neurology, 2011
Background: Microangiopathic brain lesions can be separated in diffuse lesions - leukoaraiosis - and focal lesions - lacunes. Leukoaraiosis and lacunes are caused by common cerebrovascular risk factors, but whether they represent a common entity is not ...
Stefanie eLeistner, Christian eKoennecke, Jens P Dreier, Anne K. Strempel, Markus eKathke, Alexandrina eNikolova, Peter eHeuschmann, Uwe eMalzahn, Heinrich J. Audebert, Bruno M. Mackert   +9 more
doaj   +1 more source

Mediating roles of leukoaraiosis and infarcts in the effects of unilateral carotid artery stenosis on cognition

Frontiers in Aging Neuroscience, 2022
Background and objectivesLeukoaraiosis and infarcts are common in patients with carotid artery stenosis (CAS), and CAS severity, leukoaraiosis and infarcts all have been implicated in cognitive impairments.
Kuo-Lun Huang, Kuo-Lun Huang, Ting-Yu Chang, Ting-Yu Chang, Yi-Ming Wu, Yi-Ming Wu, Yeu-Jhy Chang, Yeu-Jhy Chang, Hsiu-Chuan Wu, Hsiu-Chuan Wu, Chi-Hung Liu, Chi-Hung Liu, Tsong-Hai Lee, Tsong-Hai Lee, Meng-Yang Ho, Meng-Yang Ho, Meng-Yang Ho   +16 more
doaj   +1 more source

Confluent Thalamic Hyperintensities in CADASIL [PDF]

, 2010
Background: CADASIL is responsible for diffuse hyperintensities in the white matter on FLAIR images. These lesions are often associated with focal lesions in the basal ganglia such as lacunar infarctions.
Chabriat, Hugues, Dichgans, Martin, Düring, Marco, Guichard, Jean-Pierre, Herve, Dominique, Jacqmin, Mathilde, Viswanathan, Anand   +6 more
core   +1 more source

C-Reactive Protein and Cognition Are Unrelated to Leukoaraiosis

The Scientific World Journal, 2014
Elevated serum levels of C-reactive protein (CRP) have been associated with leukoaraiosis in elderly brain. However, several studies indicate that leukoaraiosis is associated with an increased risk of cognitive impairment. It is unknown how the effect of
Liara Rizzi, Fabricio Correia Marques, Idiane Rosset, Emilio Hideyuki Moriguchi, Paulo Dornelles Picon, Marcia Lorena Fagundes Chaves, Matheus Roriz-Cruz   +6 more
doaj   +1 more source