Results 31 to 40 of about 3,801 (177)
Stroke is the leading cause of functional disability worldwide, with increasing prevalence in adults. Given the considerable negative impact on patients’ quality of life and the financial burden on their families and society, it is essential to provide ...
Theofanis Dimaras +17 more
doaj +1 more source
Many studies have demonstrated that leukoaraiosis is associated with impaired cerebrovascular reserve function. However, the definitive hemodynamic changes that occur in leukoaraiosis are not clear, and there are many controversies.
Ying Bian +8 more
doaj +1 more source
Background Several studies have suggested that the specific stroke subtype may influence the presence of leukoaraiosis in patients with ischemic stroke.
Kim Yeong-In +7 more
doaj +1 more source
Asymptomatic Cerebral Small Vessel Disease: Insights from Population-Based Studies [PDF]
Cerebral small vessel disease (CSVD) is a common group of neurological conditions that confer a significant burden of morbidity and mortality worldwide.
Alvin S. Das +5 more
doaj +1 more source
Claudin-1 and Claudin-3 as Molecular Regulators of Myelination in Leukoaraiosis Patients [PDF]
OBJECTIVES: Leukoaraiosis is described as white matter lesions that are associated with cognitive dysfunction, neurodegenerative disorders, etc. Myelin depletion is a salient pathological feature of, and the loss of oligodendrocytes is one of the most ...
Yan Chen +4 more
doaj +2 more sources
Late-Onset Focal Epilepsy: Electroclinical Features and Prognostic Role of Leukoaraiosis
The aim of this study was to describe the electroclinical and prognostic characteristics, and to investigate the role of leukoaraiosis in outpatients with new-onset elderly focal epilepsy aged ≥60 years, referred to a tertiary epilepsy center between ...
Elena Tartara +6 more
doaj +1 more source
Heritability of Leukoaraiosis in Hypertensive Sibships [PDF]
Ischemic damage to the subcortical white matter of the brain, referred to as leukoaraiosis, is a frequent complication of hypertension-related microvascular disease and contributes to the risk of stroke and vascular dementia. A large genetic contribution to this late-life form of target organ damage was suggested by a study of elderly male
Stephen T, Turner +5 more
openaire +2 more sources
A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley +1 more source
Depression, anxiety and motivation in arterial hypertension
The vascular depression hypothesis posits that cerebrovascular diseases are a major risk factor for emotional and behavioral disorders (EBD). Arterial hypertension (AH) is one of the main causes of cerebrovascular diseases.Objective: to assess the ...
S. K. Mezhmidinova +2 more
doaj +1 more source
New Clinical Relevance of Leukoaraiosis [PDF]
To the Editor: Changes in the cerebral white matter are detected with high frequency by CT and MRI in aged individuals.1 The descriptive term leukoaraiosis, meaning rarefaction of the white matter, was proposed some 10 years ago to describe these radiological changes.2 Although the mechanism of leukoaraiosis in different clinical conditions such as ...
Pantoni, L, Inzitari, D
openaire +2 more sources

