Results 91 to 100 of about 137,740 (341)

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

open access: yesAdvanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li   +10 more
wiley   +1 more source

Optimizing Platelet and Leucocyte-Rich Plasma as Biomaterials for Ophthalmic Applications: Impact of Centrifugation Speed

open access: yesClinical Ophthalmology, 2023
Alberto Castillo-Macías,1 Judith Zavala,1 Wendy Ortega-Lara,1 Silvia Margarita García-Herrera,2 Jorge E Valdez-García1 1Instituto Tecnológcio y de Estudios Superiores de Monterrey, ITESM, Monterrey, Nuevo León, México; 2Medicina Diagnóstica, Monterrey ...
Castillo-Macías A   +4 more
doaj  

Defining an appropriate leucoreduction strategy by serial assessment of cytokine levels in platelet concentrates prepared by different methods

open access: yesAsian Journal of Transfusion Science, 2015
Background and Objectives: Different methods of platelet concentrate preparations leave behind certain number of residual leukocytes, accounting for most of the febrile nonhemolytic transfusion reactions, especially in multitransfused patients.
Daljit Kaur   +2 more
doaj   +1 more source

A Solvent‐Free, Dry‐Processed Li‐Ion Battery Enabled by Dual Binders and Nanostructured Aluminum Current Collectors

open access: yesAdvanced Functional Materials, EarlyView.
A dual‐binder dry‐processed electrode (DB‐DPE) combining PTFE and PVDF with a nanostructured Al current collector (NSA) forms a mechanically interlocked interface that significantly improves adhesion and reduces interfacial resistance. With an active material content as high as 96 wt.%, the NSA‐based DB‐DPE enables high‐mass‐loading operation (12.5 mAh
Seok Yun Kim   +4 more
wiley   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang   +13 more
wiley   +1 more source

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid   +6 more
wiley   +1 more source

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati   +2 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

open access: yesAdvanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu   +18 more
wiley   +1 more source

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