Results 211 to 220 of about 126,217 (291)

Monolobated megakaryocytes and ring sideroblasts: A morphological prelude to multihit TP53 and complex karyotype. [PDF]

Br J Haematol
Marco-Ayala J, Chen T, Ortuño FJ, Lozano ML.   +3 more
europepmc   +1 more source

Augmentation with bone marrow of donor leukocyte migration for kidney, liver, heart, and pancreas islet transplantation [PDF]

, 1994
Abu-Elmagd, K, Carroll, P, Demetris, AJ, Dodson, F, Fontes, P, Fung, JJ, Jordan, M, Rao, A, Ricordi, C, Rybka, W, Shapiro, R, Starzl, TE, Todo, S, Trucco, M, Tzakis, A, Zeevi, A   +15 more
core  

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Validation of a model of rheumatoid arthritis using mice reconstituted with patient peripheral blood mononuclear cells.

Dis Model Mech
Schuster-Winkelmann P, Weß V, Schindler M, Jensen MØ, Shaw DE, Alberton P, Schulze-Koops H, Schoenthaler S, Weinhaeusel A, Siebeck M, Gropp R, Aszodi A.   +11 more
europepmc   +1 more source

Inflammation-resolution signalling in cardiac repair, remodelling, and heart failure. [PDF]

Eur Heart J Open
Halade GV, Bäck M, Kain V.
europepmc   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Endothelial insulin-like growth factor-1 signalling regulates vascular barrier function and atherogenesis. [PDF]

Cardiovasc Res
Drozd M, Bruns AF, Yuldasheva NY, Maqbool A, Viswambharan H, Skromna A, Makava N, Cheng CW, Sukumar P, Eades L, Walker AMN, Griffin KJ, Galloway S, Watt NT, Haywood N, Palin V, Warmke N, Imrie H, Bridge K, Beech DJ, Wheatcroft SB, Kearney MT, Cubbon RM.   +22 more
europepmc   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source

Novel use of hyperbaric oxygen treatment for treatment-resistant disseminated Saksenaea and Fusarium in a patient on extracorporeal membrane oxygenation (ECMO): a case report. [PDF]

Diving Hyperb Med
Devaney B, Mathew J, Ferris S, Roberts L, Covelli C, Orosz J, Nanjayya VB, Fuller A, Millar I.   +8 more
europepmc   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source