Results 221 to 230 of about 137,740 (341)

Validation of a model of rheumatoid arthritis using mice reconstituted with patient peripheral blood mononuclear cells.

Dis Model Mech
Schuster-Winkelmann P, Weß V, Schindler M, Jensen MØ, Shaw DE, Alberton P, Schulze-Koops H, Schoenthaler S, Weinhaeusel A, Siebeck M, Gropp R, Aszodi A.   +11 more
europepmc   +1 more source

A multi-omics approach uncovers causality of IL6R on endotypes of subclinical carotid atherosclerosis and the possible role of the IL6R/OSMR pathway. [PDF]

Cardiovasc Res
Chen QS, Björck HM, Bergman O, Baldassarre D, Engström G, Gallo A, Gummesson A, Hedin U, Kurl S, Lind L, Matic L, Mulder DJ, Pirro M, Savonen K, Söderberg S, Veglia F, Tremoli E, Östgren CJ, Eriksson P, Strawbridge RJ, Gigante B.   +20 more
europepmc   +1 more source

On the participation of antibodies and complement in the antibacterial activity of an extract from rabbit polymorphonuclear leucocytes.

, 1970
J Prixová, Justine S. Garvey
openalex   +1 more source

The total leucocyte count: its utility in dengue

, 2017
Anagha A. Joshi, Balasubramaniam Gayathri, Yashica Gowda R.   +2 more
openalex   +2 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

A whole blood assay for antibody dependent phagocytosis of Plasmodium falciparum infected erythrocytes. [PDF]

Commun Med (Lond)
Rathnayake D, Hasang W, Macpherson A, Ding H, Manning L, Laman M, Ome-Kaius M, Unger HW, Ter Kuile F, Madanitsa M, Wines B, Hogarth PM, Aitken EH, Rogerson SJ.   +13 more
europepmc   +1 more source

Some studies on the production and function of the thoracic duct lymphocytes with observations on the effect of colchicine on these and other leucocytes

, 2019
Madan, Rose Krishna
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

Clinical Implications of Upregulated <i>RSAD2</i> Gene Expression in Hepatocellular Carcinoma. [PDF]

Diseases
Li L, Tang NLS, Chan SL, Johnson DR, Mo F, Koh J, Kwan TK, Hui EP, Chan LL, Lee KF, Yu SCH, Yeo W.   +11 more
europepmc   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source