Results 51 to 60 of about 40,669 (305)

Association between malnutrition and leucopenia in patients with osteosarcoma

Frontiers in Nutrition, 2022
Background and aimLeucopenia (LP) greatly limits the efficacy of chemotherapy in osteosarcoma patients. This study aimed to evaluate the nutritional status of osteosarcoma patients before chemotherapy, assess the risk of LP during the perichemotherapy ...
Haixiao Wu, Haixiao Wu, Shu Li, Shu Li, Yile Lin, Yile Lin, Jun Wang, Jun Wang, Vladimir P. Chekhonin, Vladimir P. Chekhonin, Karl Peltzer, Karl Peltzer, Vladimir P. Baklaushev, Vladimir P. Baklaushev, Kirellos Said Abbas, Kirellos Said Abbas, Jin Zhang, Jin Zhang, Huiyang Li, Huiyang Li, Chao Zhang, Chao Zhang   +21 more
doaj   +1 more source

Discordance between systemic lupus erythematosus disease activity index domain weights and their association with organ damage accrual

Arthritis Care &Research, Accepted Article.
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1‐8) assigned to each domain.
Kevin Zhang, Eric F. Morand, Sarah E. Boyd, François Petitjean, Alberta Hoi, Rachel Koelmeyer, Iolanda Miceli, Julie A. Monk, Hieu T. Nim   +8 more
wiley   +1 more source

Hematological manifestation of Pediatric Systemic Lupus Erythematosus (SLE) – A single centered cross-sectional study

Journal of Family Medicine and Primary Care
Introduction: Systemic lupus erythematosus (SLE), the commonest type of lupus, is an autoimmune multisystemic disorder that can affect any organ system of the body, especially blood vessels and connective tissues, causing widespread inflammation ...
Md Rakibul Hassan, Ashik Hossain, Joyanti Mahata, Vartika Srivastava, Sougata Sarkar   +4 more
doaj   +1 more source

Effect of doxycycline and doxycycline with carica papaya on thrombocytopenia and leucopenia in acute dengue fever patients

Journal of Family Medicine and Primary Care, 2022
Background: Dengue fever is a mosquito borne disease commonly manifest leucopoenia and thrombocytopenia. Dengue fever and its complications like bleeding manifestation can be life threatening.
Vivek Pambhar, Navgeet Mathur, Amit Mehta, Medha Mathur, Dal Chand Kumawat, Ravi Mangalia, Anjana Verma, Ashish Patyal   +7 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Endocardite infecciosa por Haemophilus aphrophilus: relato de caso Infective endocarditis due to Haemophilus aphrophilus: a case report

Jornal de Pediatria, 2008
OBJETIVO: Descrever o caso de uma criança com endocardite infecciosa causada por Haemophilus aphrophilus. DESCRIÇÃO: Menino com febre e calafrios há 20 dias.
Ricardo M. Pereira, Fabio Bucaretchi, Antonia T. Tresoldi   +2 more
doaj   +1 more source

Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin

Clinical Case Reports, 2021
Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29‐year‐old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose ...
Muhammad Salem, Ahmed El‐Bardissy
doaj   +1 more source

A pilot study of temsirolimus and body composition. [PDF]

, 2013
PurposeBody weight and composition play a role in cancer etiology, prognosis, and treatment response. Therefore, we analyzed the weight, body composition changes, and outcome in patients treated with temsirolimus, an mTor inhibitor that has weight loss ...
Janku, Filip, Kurzrock, Razelle, Naing, Aung, Parsons, Henrique A, Tsimberidou, Apostolia M, Veasey-Rodrigues, Heloisa, Wheler, Jennifer J   +6 more
core   +2 more sources

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

Persistent form of bovine viral diarrhea

Вопросы вирусологии, 2023
The review provides an analysis of literature data on the persistent form of Bovine Viral diarrhea/Mucosal disease (BVD) and is focused on virus and host factors, including those related to immune response, that contribute the persistence of the virus ...
Alexey V. Mishchenko, Vladimir A. Mishchenko, Mikhail I. Gulyukin, Andrey S. Oganesyan, Svetlana V. Alexeyenkova, Alexey D. Zaberezhny, Alexey М. Gulyukin   +6 more
doaj   +1 more source