Results 91 to 100 of about 92,971 (266)
International Journal of Cancer, EarlyView.ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg +4 more
wiley +1 more source
International Journal of Cancer, EarlyView.Thyroid diseases are common among women of reproductive age and may be related to childhood cancer, but the evidence is inconsistent. This study of childhood cancer with maternal thyroid diseases and medication use in a population‐based case‐control study using Danish registries found positive associations between maternal goiter and overall cancer ...
Chuanjie Deng +5 more
wiley +1 more source
Interdisciplinary Medicine, EarlyView.The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu +11 more
wiley +1 more source
Medicine AdvancesBackground Despite advances in understanding the principles of leukemia biology and therapeutic achievements, older patients with leukemia continue to face serious challenges.
Jing Wei, Qijian Feng, Ziyuan Lu
doaj +1 more source
Myeloid sarcoma presenting as an isolated pancreatic mass in a 3‐year‐old child
JPGN Reports, EarlyView.Abstract Myeloid sarcoma (MS) is an extramedullary tumor of myeloid precursor cells, frequently associated with acute myeloid leukemia (AML), and rarely occurring in isolation. We present a child with obstructive jaundice secondary to a pancreatic head mass.
Jappmann Kaur Monga +7 more
wiley +1 more source
Genetic analysis of primary lung interdigitating dendritic cell sarcomas
The Journal of Pathology, EarlyView.Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov +6 more
wiley +1 more source
Histiocytosis development and clinical variation through the lens of genomics
The Journal of Pathology, EarlyView.Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps +3 more
wiley +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde +4 more
wiley +1 more source
Cancer Prevalence Among Large Cohort of Individuals With Down Syndrome: Implications for Screening Guidelines. [PDF]
Cancer MedIndividuals with Down syndrome have distinctive cancer profiles as compared with the general US population. Healthcare guidelines related to cancer screenings should reflect these unique profiles. ABSTRACT Introduction It is known that individuals with Down syndrome (DS) have a significantly different spectrum of malignancies and neoplasms.
Fitzpatrick V +6 more
europepmc +2 more sources