Results 101 to 110 of about 689,537 (284)

Differential disease restriction of Moloney and Friend murine leukemia viruses by the mouse Rmcf gene is governed by the viral long terminal repeat. [PDF]

, 1991
Neonatal CxD2 (Rmcfr) and Balb/c (Rmcfs) mice inoculated with Moloney murine leukemia virus (M-MuLV) exhibited approximately equivalent time course and pathology for disease.
Brightman, BK, Fan, H, Li, QX, Trepp, DJ
core  

Genetic Basis of Acute Lymphoblastic Leukemia.

Journal of Clinical Oncology, 2017
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure rates exceeding 90% in children, it remains an important cause of morbidity and mortality in children and adults.
I. Iacobucci, C. Mullighan
semanticscholar   +1 more source

Hereditary Multiple Osteochondromas and Acute Lymphoblastic Leukemia: A Possible Role for EXT1 and EXT2 in Hematopoietic Malignancies

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hereditary multiple osteochondromas (HMO) is an autosomal dominant disorder caused by heterozygous deleterious variants in the EXT1 or EXT2 genes. While the clinical core phenotype is well established and mainly consists of bone deformities, limb length discrepancies, multiple benign bone neoplasms, and increased risk of chondrosarcoma, the ...
Francesco Comisi, Carmela Fusco, Rosamaria Mura, Carla Cerruto, Leonardo D'Agruma, Salvatore Carnazzo, Marco Castori, Salvatore Savasta   +7 more
wiley   +1 more source

Cohesins: Crossroad Between Cornelia de Lange Spectrum and Cancer Predisposition

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The cohesin complex plays crucial roles in DNA repair, chromatid separation, and gene transcription regulation. Pathogenic variants in cohesins or dysfunctional transcriptional regulators lead to cohesinopathies, a broader group of disorders including Cornelia de Lange Spectrum (CdLSp), for which the prevalence of cancer cases remains unclear.
Laura Rigotti, Stefano Rebellato, Antonella Lettieri, Silvia Castiglioni, Milena Mariani, Simona Totaro, Claudia Saitta, Cristina Gervasini, Grazia Fazio, Valentina Massa, Giovanni Cazzaniga, Angelo Selicorni   +11 more
wiley   +1 more source

An unusual initial presentation of mantle cell lymphoma arising from the lymphoid stroma of warthin tumor. [PDF]

, 2015
BackgroundWarthin tumors presenting concomitantly with a lymphoma is vanishingly rare with only 15 reported cases in English literature. Herein, we report an unusual initial presentation of a mantle cell lymphoma involving the lymphoid stroma of a ...
Arcega, Ramir S, Bhuta, Sunita, Blackwell, Keith E, Feinstein, Aaron J, Pullarkat, Sheeja T, Rao, Nagesh P   +5 more
core   +1 more source

Polyradiculoneuritis revealing an acute monoblastic leukemia 5 [PDF]

The Pan African Medical Journal, 2010
Acute polyradiculoneuritis has been frequently reported in association with malignant disorders, especially those of the lymphoid system. To date, there have been no reported cases of acute monoblastic leukemia associated with this polyradiculopathy. The
Wafa Allam, Hassan Errihani, Yahya Hsaini   +2 more
doaj  

Identification of Leukemia Subtypes from Microscopic Images Using Convolutional Neural Network

Diagnostics, 2019
Leukemia is a fatal cancer and has two main types: Acute and chronic. Each type has two more subtypes: Lymphoid and myeloid. Hence, in total, there are four subtypes of leukemia.
Nizar Ahmed, Altuğ Yiğit, Z. Işik, A. Alpkocak   +3 more
semanticscholar   +1 more source

Differential Immune Cell Infiltration in Eosinophilic and Non‐Eosinophilic CRS: Correlations With Clinical, Endoscopic, and Radiological Findings

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The pathogenesis of inflammation in eosinophilic chronic rhinosinusitis (ECRS) and non‐eosinophilic chronic rhinosinusitis (NECRS) remains poorly understood. This study aimed to assess immune cell infiltration within the sinonasal microenvironment in these conditions.
Katarzyna Czerwaty, Katarzyna Piszczatowska, Mirosław J. Szczepański, Natalia Jermakow, Nils Ludwig, Karolina Dżaman   +5 more
wiley   +1 more source

Lymphoid Progenitor Cells from Childhood Acute Lymphoblastic Leukemia Are Functionally Deficient and Express High Levels of the Transcriptional Repressor Gfi-1

Clinical and Developmental Immunology, 2013
Acute lymphoblastic leukemia (ALL) is the most frequent malignancy of childhood. Substantial progress on understanding the cell hierarchy within ALL bone marrow (BM) has been recorded in the last few years, suggesting that both primitive cell fractions ...
Jessica Purizaca, Adriana Contreras-Quiroz, Elisa Dorantes-Acosta, Eduardo Vadillo, Lourdes Arriaga-Pizano, Silvestre Fuentes-Figueroa, Horacio Villagomez-Barragán, Patricia Flores-Guzmán, Antonio Alvarado-Moreno, Hector Mayani, Isaura Meza, Rosaura Hernandez, Sara Huerta-Yepez, Rosana Pelayo   +13 more
doaj   +1 more source

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

New England Journal of Medicine, 2014
BACKGROUND Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is characterized by a gene-expression profile similar to that of BCR-ABL1-positive ALL, alterations of lymphoid transcription factor genes, and a poor outcome.
K. Roberts, Yongjin Li, D. Payne-Turner, R. Harvey, Yung‐Li Yang, Deqing Pei, K. McCastlain, L. Ding, Charles Lu, Guangchun Song, Jing Ma, J. Becksfort, Michael C. Rusch, Shann-Ching Chen, J. Easton, Jinjun Cheng, Kristy Boggs, Natalia Santiago-Morales, I. Iacobucci, R. Fulton, Ji-Rong Wen, M. Valentine, Cheng Cheng, S. Paugh, M. Devidas, I. Chen, S. Reshmi, Amy A. Smith, Erin K. Hedlund, P. Gupta, Panduka Nagahawatte, Gang Wu, Xiang Chen, D. Yergeau, Bhavin Vadodaria, H. Mulder, N. Winick, E. Larsen, W. Carroll, N. Heerema, A. Carroll, G. Grayson, S. Tasian, A. Moore, F. Keller, Melissa J. Frei-Jones, J. Whitlock, E. Raetz, D. White, T. Hughes, Jaime M Guidry Auvil, Malcolm A. Smith, G. Marcucci, C. Bloomfield, K. Mrózek, J. Kohlschmidt, W. Stock, S. Kornblau, M. Konopleva, E. Paietta, C. Pui, S. Jeha, M. Relling, W. Evans, D. Gerhard, J. Gastier-Foster, E. Mardis, R. Wilson, M. Loh, J. Downing, S. Hunger, C. Willman, Jinghui Zhang, C. Mullighan   +73 more
semanticscholar   +1 more source