Results 101 to 110 of about 157,947 (291)

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

The specific features of diagnosis of mixed-phenotype acute leukemia: A combination of B-cell antigen expressions according to the results of flow cytometry and morphological markers of myeloid differentiation in blast cells: A clinical case

Терапевтический архив, 2015
This rare type of acute leukemia, blast cells of which express myeloid and/or lymphoid markers, is mainly diagnosed using flow cytometric findings. The paper describes a clinical case of mixed-phenotype acute leukemia, in which B-cell lymphoid antigen ...
S V Gritsaev, I I Kostroma, G M Ryadnova, S A Tiranova, Zh V Chubukina, V A Balashova, M N Zenina, I S Martynkevich, N A Potikhonova, K M Abdulkadyrov   +9 more
doaj  

Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]

, 2017
Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho, Greenhalgh, David, Lee, Kang-Hoon, Lim, Debora   +3 more
core   +2 more sources

Mature T‐cell leukemia/lymphoma with an NK‐like immunophenotype: A report of 7 cases

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Distinguishing T‐cell from NK‐cell neoplasms can occasionally be challenging, as neoplastic T cells can lose T‐cell markers such as surface CD3 (sCD3) and CD5 while acquiring NK‐cell markers such as CD16, CD56, and CD94. In this study, we present a series of 7 mature T‐cell lymphoma/leukemia cases with NK‐like immunophenotypes to clarify ...
Wei J. Wang, Sa A. Wang, Hong Fang, Jeffrey L. Jorgensen, Shimin Hu, Lianqun Qiu, Jie Xu, L. Jeffrey Medeiros, Wei Wang   +8 more
wiley   +1 more source

Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor

Cell Reports, 2017
A gradual restriction in lineage potential of multipotent stem/progenitor cells is a hallmark of adult hematopoiesis, but the underlying molecular events governing these processes remain incompletely understood.
Martin Wahlestedt, Vasileios Ladopoulos, Isabel Hidalgo, Manuel Sanchez Castillo, Rebecca Hannah, Petter Säwén, Haixia Wan, Monika Dudenhöffer-Pfeifer, Mattias Magnusson, Gudmundur L. Norddahl, Berthold Göttgens, David Bryder   +11 more
doaj   +1 more source

B-1 progenitor acute lymphoid leukemia [PDF]

Blood, 2019
In this issue of Blood, Yin et al demonstrated that engineered BCL6 interacting corepressor protein (Bcor) mutation in hematopoietic stem/progenitor cells of sensitized mice induced acute lymphoid leukemia (ALL) of B-1 progenitor phenotype, which has been recently identified by them.
openaire   +2 more sources

COMIP‐001: A clinical 13‐antibody, 12‐color flow cytometry panel for optimized immunophenotyping of T/NK cells in human leukemia and lymphoma diagnostics

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract The objective of this 12‐color/13‐antibody single‐tube panel is to assist in the diagnosis of T/NK‐cell leukemias and lymphomas. In the clinical setting, the absence of a standardized T/NK‐cell panel limits inter‐laboratory data comparability, contributes to diagnostic variability, and results in redundant efforts across laboratories to design
Nicole So, Sara Monaghan, Katelynn Davis, Grant Bullock, Wendy Shallenberger, Ahmad Al‐Attar   +5 more
wiley   +1 more source

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]

, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas, Schwartz, Stefan, Hummel, Michael, Hoelzer, Dieter (Prof. Dr.), Thiel, Eckhard   +4 more
core   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Proteomic Profile Of Lymphoid Leukemia

Journal of the College of Physicians and Surgeons Pakistan, 2018
Lymphoid (or lymphocytic/lymphoblastic) leukemia, one of two major types of leukemias (lymphoid and myeloid), is divided into two subtypes, acute lymphoid leukemia (ALL) and chronic lymphocytic leukemia (CLL), depending on the maturation stage and speed of multiplication of the bone marrow lymphocytes.
openaire   +2 more sources