Results 121 to 130 of about 689,537 (284)
Analysis of childhood leukemia mortality trends in Brazil, from 1980 to 2010
Jornal de Pediatria, 2014 OBJECTIVE: Leukemias comprise the most common group of cancers in children and adolescents. Studies conducted in other countries and Brazil have observed a decrease in their mortality.This study aimed to evaluate the trend of mortality from leukemia in ...
Franciane F. Silva +2 more
doaj +3 more sources
Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia.
Blood, 2018 As a consequence of acquired or intrinsic disease resistance, the prognosis for patients with relapsed or refractory T-cell acute lymphoblastic leukemia (T-ALL) is dismal. Novel, less toxic drugs are clearly needed.
Karen L. Bride +21 more
semanticscholar +1 more source
Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor
Cell Reports, 2017 A gradual restriction in lineage potential of multipotent stem/progenitor cells is a hallmark of adult hematopoiesis, but the underlying molecular events governing these processes remain incompletely understood.
Martin Wahlestedt +11 more
doaj +1 more source
Blood, 2011 The success of cancer immunotherapy depends on productive tumor cell recognition by killer lymphocytes. γδ T cells are a population of innate-like lymphocytes endowed with strong, MHC-unrestricted cytotoxicity against tumor cells.
D. V. Correia +5 more
semanticscholar +1 more source
Biotechnology Progress, EarlyView.Abstract Epigenetic regulation plays an important role in cell fate reprogramming. Here, we found that inhibitors of epigenetic modifiers, including VPA, TSA, and 5‐Aza‐2'‐deoxycytidine, can induce phenotypic transformation from Jurkat cells into B‐cell‐like cells. When Jurkat cells were treated with 5‐Aza combined with VPA, B cell and stem cell marker
Wenjin Xi +11 more
wiley +1 more source
Hairy cell leukemia: 2020 update on diagnosis, risk stratification, and treatment
American journal of hematology/oncology, 2019 Hairy cell leukemia (HCL) and HCL‐like disorders, including HCL variant (HCL‐V) and splenic diffuse red pulp lymphoma (SDRPL), are a very heterogeneous group of mature lymphoid B‐cell disorders. They are characterized by the identification of hairy cells,
E. Maître, E. Cornet, X. Troussard
semanticscholar +1 more source
Pediatrics and Neonatology, 2021 Background: Mixed-phenotype acute leukemia (MPAL) poses a diagnostic and therapeutic dilemma. No consensus exists on the strategy to assign patients with MPAL to either lymphoid- or myeloid-directed treatment.
Tsung-Yen Chang +6 more
doaj
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source