Results 151 to 160 of about 713,469 (335)
Food Frontiers, EarlyView.Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli +8 more
wiley +1 more source
Human cancers over express genes that are specific to a variety of normal human tissues
, 2005 We have analyzed gene expression data from 3 different kinds of samples: normal human tissues, human cancer cell lines and leukemic cells from lymphoid and myeloid leukemia pediatric patients.
Altieri +21 more
core +2 more sources
Merkel Cell Carcinoma: Evolving Therapeutics, Continued Challenges
Head &Neck, EarlyView.ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine malignancy with rising incidence, influenced by ultraviolet (UV) radiation and Merkel cell polyomavirus (MCPyV). Methods This review summarizes recent advances in MCC management, based on an analysis of current literature, focusing on immune checkpoint inhibitors (ICIs)
Hunter A. Holley +6 more
wiley +1 more source
Blinatumomab in the Therapy of Acute B-Lymphoid Leukemia.
Mediterranean journal of hematology and infectious diseasesBlinatumomab, a CD19-CD3 bispecific T cell engager (BiTE), has two recombinant single-chain variable fragments that temporarily link CD3+ T cells and CD19+ B cells, leading to the T cell-mediated lysis of neoplastic B cells. Improved minimal residual disease (MRD)-negative response rates and long-term overall survival have been observed in B-ALL ...
Testa U. +3 more
openaire +4 more sources
Effect of urethane on a Transplantable Acute Lymphoid Leukemia.
Experimental Biology and Medicine, 1947 SummaryUrethane, administered intraperitoneally in subanesthetic dose, 0.75 mg per g of body weight per day in leukemic mice transplanted with leukemic cells of the 32nd to 34th transfer generations of an acute lymphoid leukemia, produces the following profound palliative effects: (1) The blood leukocytes are maintained at leukopenic levels.
openaire +3 more sources
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
New England Journal of Medicine, 2011 D. Porter +4 more
semanticscholar +1 more source
Skeletal lesions in acute lymphoid leukemia.
Haematologica, 1991 [No abstract available]
M. Pigna +4 more
openaire +2 more sources
Mechanisms of enhancer‐driven oncogene activation
International Journal of Cancer, EarlyView.Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend +2 more
wiley +1 more source