Results 161 to 170 of about 92,971 (266)

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Characterizing the impact of MLL fusion variants and fusion partners on leukemia plasticity using a human CRISPR-engineered MLL-rearranged leukemia model. [PDF]

Neoplasia
Radszuweit P, Fitzel R, Bruestl S, Hentrich T, Korkmaz F, Mankel B, González-Menéndez I, Rudat S, Marschalek R, Erkner E, Keppeler H, Schairer R, Luib L, Mezger M, Quintanilla-Martinez L, Schulze-Hentrich J, Lengerke C, Schneidawind D, Schneidawind C.   +18 more
europepmc   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Development of Colonic Polyposis in a Woman With Chronic Myeloid Leukemia Treated With Dasatinib. [PDF]

Case Rep Hematol
Pelaez G, Yildiz BS, Candan M, Ismail M, Vacca F, Ruzinova MB, Ballentine S, Byrnes K, Ghobadi A.   +8 more
europepmc   +1 more source

Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation

European Journal of Haematology, Volume 117, Issue 1, Page 132-143, July 2026.
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Mamdouh Skafi, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

When pseudo-Richter transformation hits the spleen: a case report and literature review. [PDF]

J Hematop
Onieva R, Rama L, Blázquez C, Astorga R, Escudero L, Ramila ME, Ramos MC, Papaleo N.   +7 more
europepmc   +1 more source

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer

Immunology, Volume 178, Issue 3, Page 377-386, July 2026.
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Alef Batista Bezerra Barros, Gabriel Augusto Leite, Arthur Gomes de Andrade, Maria Danielma dos Santos Reis, Luiz Henrique Agra Cavalcante‐Silva, Marvin Paulo Lins   +5 more
wiley   +1 more source

A Recently Recognized and Underdiagnosed Entity of Splenic Diffuse Red Pulp Small B-Cell Lymphoma: A Report of Two Cases. [PDF]

Cureus
Belkadi S, El Boutahiri I, Oumayma H, Erradi G, Regragui S.   +4 more
europepmc   +1 more source

Lymphoma, multiple myeloma and leukaemia incidence in regions of Belarus most heavily contaminated by the Chernobyl accident

International Journal of Cancer, Volume 158, Issue 12, Page 3161-3172, 15 June 2026.
What's new? The 1986 Chernobyl accident led to widespread radioactive contamination across parts of Europe, with elevated childhood leukaemia rates observed in heavily affected areas of Ukraine. Data on long‐term haematological and other non‐thyroid cancer risk in the general population in heavily contaminated regions, however, remain limited.
Ljubica Zupunski, Alesia Yaumenenka, Ilya Veyalkin, Victor Minenko, Pavel Moiseyev, Joachim Schüz, Tatiana Kukhta, Sergey Trofimik, Richard Harbron, Vladimir Drozdovitch, Evgenia Ostroumova   +10 more
wiley   +1 more source

Dueling Malignancies: A Rare Case of Concurrent Chronic Lymphocytic Leukemia (CLL) and Chronic Myeloid Leukemia (CML) in a Multimorbid Elderly Patient. [PDF]

Cureus
Alzahim M, Alakedi A, Almugren O, Khoja O, Alias N, Abdelgader A.   +5 more
europepmc   +1 more source