Spectrum of Movement Disorders in Hematological Malignancies: A Comprehensive Systematic Review of Clinical Phenotypes, Mechanisms, and Outcomes. [PDF]
Garg RK +6 more
europepmc +1 more source
Hairy Cell Leukemia With Aberrant CD5 and CD23 Expression: A Case Report and a Brief Literature Review. [PDF]
Alameddine Z +4 more
europepmc +1 more source
In a real‐world matched cohort study of treatment‐naïve TP53 wild‐type CLL patients, venetoclax plus obinutuzumab demonstrated significantly longer time to next treatment and improved 4‐year overall survival compared to first‐line acalabrutinib. Despite higher rates of cytopenias and infections, the venetoclax‐based regimen showed superior efficacy ...
Po‐Wei Liao +4 more
wiley +1 more source
Blastoid Mantle Cell Lymphoma in the Leukemic Phase: Resolving a Morphological Dilemma Through Flow Cytometry. [PDF]
Kundu A, Giri S, Basu A.
europepmc +1 more source
ABSTRACT APL presenting as an extramedullary mass is exceedingly rare. Here, we describe extramedullary APL causing cauda equina syndrome, underscoring the diagnostic challenges associated with an atypical presentation, highlighting the complexity of distinguishing extramedullary APL from other conditions, and discussing the stepwise approach to ...
Amir Ali +8 more
wiley +1 more source
Unusual Nasopharyngeal Localization of Chronic Lymphocytic Leukemia: A Case Report. [PDF]
Fadi M +4 more
europepmc +1 more source
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra +7 more
wiley +1 more source
A microRNA expression signature in infant t(4;11) KMT2A::AFF1+ BCP-ALL uncovers novel therapeutic targets. [PDF]
Malouf C +13 more
europepmc +1 more source
SIRT1: Protean roles at the nexus of health, disease, and therapeutics
SIRT1 serves as a central regulator linking metabolism, stress responses, and disease. It influences diverse processes, including transcriptional and posttranscriptional gene expression and protein activity, inflammation, mitochondrial function, and cell survival, through the deacetylation of multiple protein targets. While SIRT1 often plays protective
Brahim Chaqour
wiley +1 more source
Venetoclax as a trigger for autoimmune hemolytic anemia in secondary acute myeloid leukemia: A case report. [PDF]
Benallaoua K +4 more
europepmc +1 more source

