Results 261 to 270 of about 713,469 (335)

First report of B-lymphoblastic leukemia harboring LRRFIP1::FGFR1 fusion: expanding the clinical spectrum of myeloid/lymphoid neoplasms with tyrosine kinase gene fusions. [PDF]

Ann Hematol
Chen X, Ren Y, Jin Y, Li X, Ma X, Cao P, Zhang Y, Wang F, Liu H, Wang W.   +9 more
europepmc   +1 more source

Sequence Diversity and Expression Profiles of T Cell Receptor Beta Chain Constant Genes TRBC1 and TRBC2 in Canine Lymphoid Tumour Cell Lines and Normal Lymphocytes

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT The subtle sequence diversity and mutually exclusive expression patterns of T cell receptor beta chain constant genes, TRBC1 and TRBC2, in mature human T cells, provide the basis for immune‐targeting strategies designed to eliminate clonally expanded malignant T cells while sparing a subset of normal T cells capable of maintaining ...
Marek Pieczka, Leszek Moniakowski, Aleksandra Studzińska, Dominika Kubiak‐Nowak, Aleksandra Pawlak, Arkadiusz Miazek   +5 more
wiley   +1 more source

Single-cell Transcriptional Atlas of Human Hematopoiesis Reveals Genetic and Hierarchy-Based Determinants of Aberrant AML Differentiation. [PDF]

Blood Cancer Discov
Zeng AGX, Iacobucci I, Shah S, Mitchell A, Wong G, Bansal S, Chen D, Gao Q, Kim H, Kennedy JA, Arruda A, Minden MD, Haferlach T, Mullighan CG, Dick JE.   +14 more
europepmc   +1 more source

Utility of Cytochemical and Flow Cytometry Detection of Alkaline Phosphatase for Differential Diagnosis of CD34+ Acute Leukaemia in Canines

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Alkaline phosphatase (ALP) enzymatic activity has been proposed as a marker for distinguishing canine acute leukaemia (AL) subtypes (i.e., myeloid vs. lymphoid). However, ALP enzymatic activity has not been fully evaluated in CD34+ AL. Determine whether ALP enzymatic activity can differentiate CD34+ AL subtypes in dogs and distinguish CD34+ AL
Megan Aalto, Janna Yoshimoto, Jillian Nolan, Kenzie Olsen, Dylan Ammons, Emily Rout, Anne C. Avery, R. Adam Harris   +7 more
wiley   +1 more source

Coexistence of Essential Thrombocythemia and Waldenström Macroglobulinemia: A Case Report. [PDF]

Case Rep Hematol
Wallace M, Mathey B, Yeung CCS, Appelbaum JS, Wallace M.   +4 more
europepmc   +1 more source

Advancements in genetic analysis: Insights from a case study and review of next‐generation sequencing techniques for veterinary oncology applications

Veterinary Clinical Pathology, EarlyView.
Abstract Acute myeloid leukemia (AML) poses significant challenges in veterinary medicine, with limited treatment options and poor survival rates. While substantial progress has been made in characterizing human AML, translating these advancements to veterinary practice has been hindered by limited molecular understanding and diagnostic tools. The case
R. Adam Harris, Jillian Nolan, Dylan Ammons, Samantha Beeson, Douglas Thamm, Anne Avery   +5 more
wiley   +1 more source

A cross-sectional analysis of the global burden of childhood leukemia from 1990 to 2021. [PDF]

J Cancer Res Clin Oncol
Wang P, Cui J, Ni Z, Qian Z, Zhan H, Zhang H, Ye W, Meng W, Bai R.   +8 more
europepmc   +1 more source

A Machine Learning‐Optimized Immunogenic Cell Death Signature Reveals Tumor Immunogenicity and the Immunotherapy Response of Pancancer

MedComm – Future Medicine, Volume 4, Issue 4, December 2025.
This study introduces an innovative adversarial validation (AV) strategy integrated with machine learning to mitigate the problem of data set shift and enhance analyses of pan‐cancer immunogenicity. It identifies key immunogenic cell death‐related biomarkers and demonstrates their predictive potential for survival outcomes and responses to PD‐1 ...
Li Qiu, Danqing Huang, Yuening Zhang, Yingying Zhou, Ming Luo, Chengdong Zhang, Ying Huang, Mingyuan Zou, Wenlong Lu, Hui Liu, Shaowei Liu, Haoyang Huang, Kaiwen Ye, Yuan Hui, Cheng Tang, Zilong Yan, Xi Zhong, Zhiguo Luo, Hongxin Huang, Ming Zhou, Guangshuai Jia, Qibin Leng, Jun Liu   +22 more
wiley   +1 more source

Pediatric computed tomography scan and subsequent risk of malignancy: a nationwide population-based cohort study in Korea using National Cancer Institute dosimetry system for computed tomography (NCICT). [PDF]

BMC Med
Han S, Soh J, Nah S, Han K, Jung JH, Park J, Hwang Y, Lee C, Hong JY.   +8 more
europepmc   +1 more source

Large‐Bore Vacuum Suction Biopsy of Pediatric Soft Tissue Tumors: A 5‐Year Retrospective Analysis of Safety and Effectiveness

Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Introduction Percutaneous large‐bore vacuum suction biopsy (LBVSB) is an innovative alternative to open surgical biopsy and minimally invasive image‐guided percutaneous core needle biopsy (PCNB) for pediatric soft tissue tumors. This study reviews our experience using this modality.
Abhinav R. Balu, Shankar Rajeswaran, Nitin R. Wadhwani, Ian Gelarden, Elizabeth Sokol, Joseph R. Ness, Darshan E. Variyam, Timothy Lautz, Joe B. Baker   +8 more
wiley   +1 more source